Conserved Protein Domain Family
PRK07006

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PRK07006: PRK07006 
isocitrate dehydrogenase; Reviewed
Links
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Statistics
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PSSM-Id: 180792
Aligned: 222 rows
Threshold Bit Score: 844.727
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
114565934   1 MPVGEKIRVENGVLKVPDHPIIPFIEGDGTGPDIWAAASRVLEAAVDKAYKGQKSIVWKEVLAGEKAFQQTGEWLPQETI 80 
23099622    1 MTQAEKIVVENGKMNVPDTPIIPFIEGDGTGPDIWASAQKVIEAAVDKAYDGKKSIEWMEVYAGQKAYDKTGEWLPKDTL 80 
169829559   8 NRMSNKIVVENGVLNVPNNPVIPFIEGDGIGPDIWAAASRVIDAAVEKAYNGEKKIEWLEVLAGEKAFNQTGEWLPQETL 87 
172058217   3 TIQGENITVTDGTLNVPNSPIIPFIIGDGTGPDIWNAAVRVFDAAVEKAYNGEKKIEWKEVYAGEKAFNKTGNWLPEETL 82 
226224167   1 --MSQKIQVENGVLKTPNNPVIPFIEGDGTGPDIWAAAKRVLDAAVKKAYNGEKEIAWKEVLAGEKAFKQTGEWLPQATL 78 
226310977   8 PTVGEKITVDNGKLVVPNNPVIPFIEGDGTGPDIWKASVRVLDAAVEKAYKGEKKIAWFEVFAGEKSFNQYSEWLPEDTL 87 
229916396   2 LTQGQKITVENGVLNVPNVPTVPFIIGDGTGPDIWNAAVRVFDAAVEKAYGGDKKIEWMEVYAGEKAYNEKGEWLPTETL 81 
258512310  10 PTEGEPITLVDGKLNVPDHPIIPFIEGDGTGPDIWRAAQRVFDAAVEKAYGGKRKIAWYEVYAGEKAYNMFGEWLPQDTL 89 
289434846   1 --MSQKIQVENGVLKTPNNPVIPFIEGDGTGPDIWAAAKRVLDAAVKKAYNGEKEIAWKEVLAGEKAFKQTGEWLPQATL 78 
116872995   1 --MSQKIQVENGVLNTPNNPVIPFIEGDGTGPDIWAAAKRVLDAAVKKAYNGEKEIAWKEVLAGEKAFKQTGEWLPQATL 78 
114565934  81 DTIREYIIAIKGPLTTPIGGGIRSLNVALRQELDLYTCLRPVRYFEGVPSPVKRPEDTDMVIFRENTEDIYAGIEYPRGS 160
23099622   81 DKINEYKIAIKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRYFEGVPSPVKRPEEVDMVIFRENTEDIYAGIEWQKGS 160
169829559  88 DKINEYLIAIKGPLTTPIGGGIRSLNVALRQQLDLYVCLRPVRHFDGVPSPVKRPEDVDMVIFRENTEDIYAGIEFESGS 167
172058217  83 DLIREHIIAIKGPLTTPVGGGIRSLNVALRQELDLYTCLRPVRYFTGVPSPVKRPEDTDMVIFRENTEDIYAGIEYASGS 162
226224167  79 DTIDEYLIAIKGPLTTPIGGGIRSLNVALRQELDLYVCLRPVRYFKGVPSPVKRPEDTDMVIFRENTEDIYAGIEFKEGS 158
226310977  88 TAVREYLIAIKGPLTTPVGGGIRSINVALRQELDLYACVRPVQYFDGVPSPVKHPELTDMVIFRENTEDIYAGVEWAEGT 167
229916396  82 DQIREYLIAIKGPLTTPVGGGIRSLNVALRQELDLYTCLRPVRYFTGVPSPVKRPEDTDMVIFRENTEDIYAGIEYASGS 161
258512310  90 TALSEYIVSIKGPLTTPVGGGIRSLNVAVRQELDLYVCQRPVRYFQGVPSPVKHPELVDMVIFRENSEDIYAGIEWQAGT 169
289434846  79 DTIDEYLIAIKGPLTTPIGGGIRSLNVALRQELDLYVCLRPVRYFKGVPSPVKRPEDTDMVIFRENTEDIYAGIEFKEGS 158
116872995  79 DTIDEYLIAIKGPLTTPIGGGIRSLNVALRQELDLYVCLRPVRYFKGVPSPVKRPEDTDMVIFRENTEDIYAGIEFKEGS 158
114565934 161 EESDKLLKFLQEELGVKNIRFPGSSGIGIKPVSEEGSKRLVRAAINYALNEGRRNVTLVHKGNIMKYTEGAFKQWGYDLA 240
23099622  161 DEVKKVINFLKEEMGVKNIRFPETSGIGVKPVSEEGTKRLVRSAIDYALNEGRKNVTLVHKGNIMKFTEGAFKNWGYEVA 240
169829559 168 EQAQKIINFLQSEFGVNQIRFPETSGIGVKPVSKEGTERLVRSAIEYAIKHKRPSVTLVHKGNIMKFTEGGFKKWGYELA 247
172058217 163 EEAQKLLNFLQTEMGVNKIRFPETSGLGIKPISKEGTERLVRAAIEYALENKRASLTLVHKGNIMKFTEGAFKNWGYELA 242
226224167 159 EESKKLIDFLKSEFGVDKIRFPETSGIGIKPISKEGTERLVRSAIEYAIKEDRKSLTLVHKGNIMKFTEGAFKNWGYDLC 238
226310977 168 PEVKKVIDFLQNEMGVKKIRFPETSGIGIKPVSKDGTERLVRAAINYAIENNRKSVTLVHKGNIMKFTEGAFKTWGYAVA 247
229916396 162 DEVKKLIKFLQDEMNVNKIRFPETSGIGIKPVSSEGTERLVRAAIEYAIANNRKSLTLVHKGNIMKFTEGAFKNWGYALA 241
258512310 170 PEVKKVIEFLQKEMGVKKIRFPETSGIGVKPVSREGTERLVRAAIEYALRHKRKSVTLVHKGNIMKFTEGAFKNWGYELA 249
289434846 159 EESKKLIAYLKSEFGVDKIRFPETSGIGIKPISKEGTERLVRSAVEYAIKEGRKSLTLVHKGNIMKFTEGAFKTWGYDLC 238
116872995 159 EESKKLIAFLKSEFGVDKIRFPETSGIGIKPISKEGTERLVRSAIEYAIKEGRKSLTLVHKGNIMKFTEGAFKNWGYDLC 238
114565934 241 ESEFGDKVFTWDQYDRIkeekgtaaadqaqKEAEEAGKLIIKDAIADIFLQQILTRPNEFDVVATLNLNGDYISDALAAQ 320
23099622  241 EQEYGDKVFTWAEYDRIveaegkdaankaqDEALASGKILVKDAIADIFLQQVLTRPKEFDVVATMNLNGDYISDALAAQ 320
169829559 248 EKEFADQTFTWNQYDAIkaeqgeeaankaqSDALAAGKILVKDSIADIFLQQILTRPTEFDVVATMNLNGDYISDALAAQ 327
172058217 243 EREYAEHVFTWNQYDRIkdeegadaankaqSEAEAAGKLIVKDSIADIFLQQILTRPKEFDVVATMNLNGDYISDALAAQ 322
226224167 239 EREYGDKVFTWNEYDRIkeaegtevadakqKEALAAGKILVKDSIADIFLQQILTRPAEFDVVATMNLNGDYISDALAAQ 318
226310977 248 EAEFGDKVFTWAQYDRIkaeggd--adkaqKEAEAAGKIIVKDVIADAFLQQILTRPAEYDVVATLNLNGDYVSDALAAQ 325
229916396 242 EAEYGDKVFTWAQYDRIkeesgeaaaneaqSKAEAEGKIIVKDSIADIFLQQILTRPREFDVVATMNLNGDYISDALAAQ 321
258512310 250 EREFSDKVFTWAQYDRIkaekgqeaadaaqKEAIEAGKLIVKDVIADAFLQQILTRPAEYDVIATLNLNGDYISDALAAQ 329
289434846 239 EREYADKVFTWNEYDRIkevegteaadakqKEALASGKILVKDSIADIFLQQILTRPAEFDVVATMNLNGDYISDALAAQ 318
116872995 239 EREYGDKVFTWNEYDRIkeaegaevadakqKEALSEGKILVKDSIADIFLQQILTRPAEFDVVATMNLNGDYISDALAAQ 318
114565934 321 VGGIGIAPGANINyvTGHAIFEATHGTAPKYAGLDKVNPSSVILSGELMLRHLGWNEAADLIIMAIGKTIASKVVTYDFA 400
23099622  321 VGGIGIAPGANINydTGHAIFEATHGTAPKYAGLDKVNPSSVILSAVLMLEHLGWREAADLITKSMDKTIGSKVVTYDFA 400
169829559 328 VGGIGIAPGANINyvTGHAIFEATHGTAPKYAGLDKVNPSSVLLSGVLMLEHLGWQEAADMITKSVEQTISSKVVTYDFA 407
172058217 323 VGGIGIAPGANINymTGHAIFEATHGTAPKYAGLDKVNPSSVILSGEMMFRHLGWNEVADLIIQSMEKSIEGKVVTYDFA 402
226224167 319 VGGIGIAPGANINylTGHAIFEATHGTAPKYAGLDKVNPSSVILSGTLLLEHIGWGEAAALINQSMEKTIAAKTVTYDFA 398
226310977 326 VGGIGIAPGANINylTGHAIFEATHGTAPKYAGLDKVNPSSVILSGEMMLRHLGWNEAADLIINSMEKTISAKTVTYDFA 405
229916396 322 VGGIGIAPGANINyiTGHAIFEATHGTAPKYAGLDKVNPSSVILSGEMMLRHMNWNEAADLIINSMEKTIASKVVTYDFA 401
258512310 330 VGGIGIAPGANINyeTGHAVFEATHGTAPKYAGLDKVNPGSVILSGVMMFEYMGWQEAADLITRAMEKTIAQKIVTYDFA 409
289434846 319 VGGIGIAPGANINylTGHAIFEATHGTAPKYAGLDKVNPSSVILSGTLLLEHIGWSEAAELINLSMEKTIAAKTVTYDFA 398
116872995 319 VGGIGIAPGANINylTGHAIFEATHGTAPKYAGLDKVNPSSVILSGTLLLEHIGWGEAAALINHSMEKTIAAKTVTYDFA 398
114565934 401 RLMEDAQEVKCSGFADALIANM 422
23099622  401 RLMDGAKEVKCSEFGQELIKNM 422
169829559 408 RLMDGATEVKCSEFANELIKNL 429
172058217 403 RLMDGATEVKCSEFADELIKNM 424
226224167 399 RLMDGATEVKCSEFADELIKNF 420
226310977 406 RLMEGAKELKCSEFADALIQNM 427
229916396 402 RLMDGATEVKCSEFADELIKNM 423
258512310 410 RLMEGATEVKCSEFGDHIIQNM 431
289434846 399 RLMDGATEVKCSEFADELIKNF 420
116872995 399 RLMDGATEVKCSEFADELIKNF 420
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