Conserved Protein Domain Family
ddl

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PRK01966: ddl 
D-alanine--D-alanine ligase
Links
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Statistics
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PSSM-Id: 234993
Aligned: 450 rows
Threshold Bit Score: 309.744
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
23464945   34 MAKKRVVVLYGGRADEHSISCISTAGVLGAMDTERFEPIPVGITKDgKWIINGEDPRGWNldggelptvkITPESRPVML 113
29349121    1 -MKRTIAIVAGGDTSEFHVSLRSAQGIYSFIDKEKYTLYIVEMQGT-RWEVQLPDGAKAP----------VDRNDFSFML 68 
34540521    1 MKKPIVAVIAGGYSGEHSVSLKSAAGILSWLGSEPFSTFLVLIERD-RWSVRVSEQREVP----------LDKNDFSFDL 69 
150003135   1 -MKRTIAIVAGGDSSELVVSLRSAQGLYSFIDKERYNLYIVEMEGH-RWEVVLPDGSKTP----------IDRNDFSFME 68 
150009273   1 -MKKNIAIVAGGDSSEIVISLKSADGIYSFIDKDKYNLYIAIVKRD-EWAVILPSGEHTP----------IDKNDFSFKE 68 
188994624   1 MKKPIVAVIAGGYSGEHSVSLKSAAGILSWLGSEPFSAFLVLIERD-RWSVRVSEQREVP----------LDKNDFSFDL 69 
294674880   3 NLKRTIAIVCGGDSSEHDVSLRSAQGLYSFFDKERYNVYIVDIKGQ-DWHVELPDGTTAK----------IDRNDFSFME 71 
302345910   3 DSKRTIAIVCGGDSSEHDVSMRSGQGLYSFFDKERYNIYIVDVKGI-DWNVELPDGSLAP----------IDKNDFSFVM 71 
212550473   1 --MKNVAIVSGGYSSECVISLKSAEEVYLSIDKTRYNPYIVLITRN-GWTVQGGNKTEFP----------INKNDFSFIY 67 
255531745   1 -MKKKIALLTGGTTGEWVVSVKSAATIAQNLDADKFDVYKIMLTQQ-GWFYEPADSVKIE----------VDRNDFSINL 68 
23464945  114 DPSRGqdgffigepshinsadsgfgtsfvsmsdpemhhvltslgHVDAVLPVLHGPYGEDGTVQGLLEMMGVPYVGCGVF 193
29349121   69 GTEKI---------------------------------------RFDFAYITIHGTPGEDGRLQGYFDMMHIPYSCCGVL 109
34540521   70 DGERI---------------------------------------RFDYAYITIHGTPGENGLLQGYLDMIGIPYNTGDTL 110
150003135  69 NGEKK---------------------------------------QFDFAYITIHGTPGENGILQGYFDLLGIPYSSCNVL 109
150009273  69 NGVTR---------------------------------------HFDFAYITIHGTPGEDGRLQGYFDMIGMPYSSCGML 109
188994624  70 DDERI---------------------------------------RFDYAYITIHGTPGENGLLQGYLDMIGIPYNTGDTL 110
294674880  72 NGEAK---------------------------------------IFDYAYITIHGTPGENGLLQGYFDLIGLPYSTSGVL 112
302345910  72 NGERV---------------------------------------EFDYAYITIHGQPGENGVMQGYFDLIQIPYSTGGVL 112
212550473  68 KGKQI---------------------------------------RFDFAYIIIHGTPGEDGLLQGYLDILNIPYSCCGVL 108
255531745  69 KGKKV---------------------------------------KFEGVFIAIHGSPGEDGKLQGYFDMLGIPYTTCDAL 109
23464945  194 ASAACMDKHYTKVVLDAAG-IPTAPGVTVDARNFtaaDVLAEIEdAGLTYPLFVKPSRAGSSFGVTKVEkaddretQQDR 272
29349121  110 AAAITYDKFTCNQYLKAFG-VRIAESLLLRQGQS---VSDEDVM-EKIGLPCFIKPSLGGSSFGVTKVK-------TKEQ 177
34540521  111 VESLTFNKYVCNRFLSGFG-IRIADSMRLTGRDTq--PDVADLI-ARMGLPLFVKPNVGGSSIATTKVV-------EAAQ 179
150003135 110 VSAMTFNKFTCNQYLKGFG-IRVAESLILRKGFE---ITDEEVI-NKIGLPCFIKPNAGGSSFGVTKVK-------TKED 177
150009273 110 VSALTFNKYVCNHYLKDFG-VKIAASIHLFKGET---ITDEEVV-TRLGLPIFVKPNDGGSSFGVTKVK-------EVSA 177
188994624 111 VESLTFNKYVCNRFLSGFG-IRIADSMRLTGRDTq--PDVADLT-ARMGLPLFVKPNVGGSSIATTKVV-------EAAQ 179
294674880 113 VEAMTFDKFVLNQYLRGYG-VKVADSLLIRKGYEe-lVSDDEIE-ERIGMPCFVKPAADGSSFGVSKVK-------EKDM 182
302345910 113 VEALTFDKYVLNNYLRGFG-IKVADSILLRRGEE---YDEAEIE-KRLGMPCFVKPAADGSSFGVSKVK-------NIDQ 180
212550473 109 SASITFNKYFCNNYLRGFG-VETAKSILLKQREQi--ISPERII-DKLGLPLIVKPNDGGSSFGVTKVT-------NITQ 177
255531745 110 TSAVTMNKGYTKAIVDGIAeLNIAKSAQIFKGTP---YSLEQIK-KTLKVPYFVKPNNGGSSIGMSKVN-------HPDD 178
23464945  273 LAAAIATAGEHDWKVLVEQGIDGREIECAVLCpkagdE---PE--ASWPGEIVLd--hQ-----N-DdqFYDFDSKYMDA 339
29349121  178 IQPAIVKAFEEAQEVLVEAFMEGTELTCGCYKtk--dK---TV--IFPPTEVVT----------H-Ne-FFDYDAKYNGQ 238
34540521  180 LLPAIEQAFSEGEEVMIERLICGTEVTCGAFLr----K---KEvvALPVTEVVA----H-----N-E--FFDFDAKYN-G 239
150003135 178 IQPAIEKAFEESDEVMIEAFMKGTEITCGCYKts--dK---EV--VFPITEVVS----------A-Ne-FFDYGAKYNGE 238
150009273 178 IQPAIAKAFGEGREVILERFIDGTEVTCGCYKve--gK---EV--VFPLTEVVT----------N-Ne-FFDFDAKYNGQ 238
188994624 180 LLPAIGQAFSEGEEVMIERLICGTEVTCGAFLr----K---KEvvALPVTEVVA----H-----N-E--FFDFDAKYNGA 240
294674880 183 LAPAIRKAMLESPEIMVESYLEGTEISIGVYK-----TkekAV--VLPATEVVT----------SnE--FFDYDAKYNGQ 243
302345910 181 LAPALRVAFMQSDEVMIEAFMDGMEISQGVYKt----K---DKavVFPATEVVT----S-----N-E--FFDYNAKYN-G 240
212550473 178 IQLAIRNAFNEGEGVLIESFIPGTEITCGYYKt----K---NKqvTLPITEIIS----K-----N-D--FFDFEAKYNPG 238
255531745 179 LQAAIDRAFKEDSQILIEEFISGREFTIGVVK---------------LDGEITVlpatEvetakE----FFDFEAKYTPG 239
23464945  340 SaSHVEVPANLPVSVLEDVRDVARRAFKAVDGAGLSRVDTFV-TPD-GT--VMVNEINTMPGFTPISMYPKAWDATGVSY 415
29349121  239 --VDEITPARISDELTNRVQMLTSAIYDILGCSGIIRVDYIV-TAG-EK--INLLEVNTTPGMTTTSFIPQQVRAAGLDI 312
34540521  240 A-VEEITPARISDEATRLIQTMTARIYELLNARGIIRVDYIIeADGi----PTLLEVNTTPGMTPTSFIPQQVRAAGMDM 314
150003135 239 S--QEITPARLPEDTAERVRLLTSAIYDILGCSGLIRIDYII-TEG-EK--VNLLEINTTPGMTATSFIPQQVRAAGLDI 312
150009273 239 --VDEITPARISTELTELIQCETSRIYDILGAKGLIRVDYII-PAD-GE--PVLLEINTTPGMTATSFIPQQVRAAGLDI 312
188994624 241 --VEEITPARISDEATRLIQTMTARIYELLNARGIIRVDYII-EAD-GI--PTLLEVNTTPGMTPTSFIPQQVRAAEMDM 314
294674880 244 --VQEITPARLPEDVTERVRQITSHIYDILHCNGIIRIDFII-SKE-GS--ISMLEVNTTPGMTATSFIPQQVRAAGLSM 317
302345910 241 Q-VEEITPARMSDETAKRVAAETSCIYDILHANGIIRIDYIIsKDKdGKdvINMLEINTTPGMTVTSFIPQQVRAAGLDI 319
212550473 239 M-VEEITPARISKKLTDEIQTLTAHIYDWVGAKGIIRIDYIIsPKKe----IKMLEVNTIPGMTATSFIPQQIRAAGLNL 313
255531745 240 V-ATETTPAPIRKETLERVTQIVKNVYLKLNCRGVVRIDFILnGDE-GD--FYFIEINTIPGQTATSFIPQQVAAAGMKL 315
23464945  416 TELITRLIEGVLR 428
29349121  313 KDVMTDIIENKF- 324
34540521  315 KEVLCTIIRDGLN 327
150003135 313 KDVMTDIIENKF- 324
150009273 313 KDVMTDIIEDELK 325
188994624 315 KEVLCTIIRDGLN 327
294674880 318 TDVLTEIVENQFD 330
302345910 320 KNVLSDIVENQFK 332
212550473 314 KEILTEIIESI-- 324
255531745 316 NDFYTKLIRETIG 328
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