3BK6


Conserved Protein Domain Family
SPFH_eoslipins_u1

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cd08826: SPFH_eoslipins_u1 
Click on image for an interactive view with Cn3D
Uncharacterized prokaryotic subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
This model summarizes a subgroup of the stomatin-like protein family (SLPs or slipins) that is found in bacteria and archaebacteria. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Bacterial and archaebacterial SLPs remain uncharacterized. This subgroup contains PH1511 from the hyperthermophilic archaeon Pyrococcus horikoshi.
Statistics
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PSSM-Id: 259808
Aligned: 51 rows
Threshold Bit Score: 243.575
Created: 7-Jun-2010
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
trimer
Conserved site includes 33 residues -Click on image for an interactive view with Cn3D
Feature 1:trimer interface [polypeptide binding site]
Evidence:
  • Structure:3BK6: Pyrococcus horikoshii Stomatin core domain homotrimer; contacts at 4.0A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1     ########  ##         #       ###            ## ###                            # 
3BK6_A      1 MIFEKAVIVDLRTQVLDVPVQETITKDNVPVRVNAVVYFRVVDPVKAVTQVKNYIMATSQISQTTLRSVIGQAHLDELLS 80  Pyrococcus horikoshii
EKY20631   49 PIFQTMMMVDVRSTPIDVPKQEVITKDNVTVGVDAVVYFRVINAPKAVLETTNYIYATSQFAQAALRDVTGNVDMDDLLA 128 Capnocytophaga sp....
AGC41497  119 PVMDTALFVDTRLLTLDIPHQQVITRDNVPVAVDGVIFFMVKDTERAVVTVQDYRYAISQYAQAALRDVIGSMTLDELLS 198 Myxococcus stipita...
ABC44202   52 PLIQSWERVDMRVKAVDVPRQESITRDNVTVEIDAVIYYQVRDAEKAILEVEEYMYATQQLAQTTMRNIVGEVDLDALLA 131 Salinibacter ruber
CAN97523   50 PGIQELRRIDTRMKNRDLLQQMVITRDNVTTMVDAVVYYRVVDPEKATLAVENYETAMKDRAKVVLRDVVGETRLDELLA 129 Sorangium cellulos...
EKE21015   46 PVFQSYQKVDMRIKAVDVPDQEAITKDNISVKVNAVIYYKVKDANKAIIEVENFFYAVSQLAQTTMRNVVGEVNLDELLS 125 uncultured bacterium
AFM11870   49 PIVQRMVRVDMRIRTLDVMKQQIMTKDNVPVHVNAAIFFKVENPEQAIIQVQDYQYAIAQYAQTALRDVIGGKTLDTLLV 128 Turneriella parva ...
ACL46907  107 PVIEYVRFVDTRTRVINIPRQKVITRDNVPASIDGALFFRIIIPAKAITVIEDFRFAIAQYAQAALRDVVGGLTLDEMLS 186 Cyanothece sp. PCC...
EAR17142   40 PLVETIQKVDIRVITINIVSQEVMTEDNVPCSIDGVVFFRIRDPEKAVLEVEEYNFAITQLSQAALRDVCGKVELDTILS 119 Robiginitalea bifo...
BAE50616   71 PFIQNLIPVDIRLAVMEVPTQDVISRDNVSVKVTAVVYYRVSNAMKAVLEVANYREAVSQLAQITTRSTLGSHTLDQLLG 150 Magnetospirillum m...
Feature 1      ##                        #  ####### #   #   #                                 
3BK6_A     81 ERDKLNMQLQRIIDEATDPWGIKVTAVEIKDVELPAGMQKAMARQAEAERERRARITLAEAERQAAEKLREAAEIISehP 160 Pyrococcus horikoshii
EKY20631  129 KREEISQQIKEIVDAETDKWGIDVENVKIQNIELPGDMKRAMAKQAEAERERRANIINADGEKAAAETLAQAAEILAktQ 208 Capnocytophaga sp....
AGC41497  199 ERDQIQSRIAQAVEERSMAWGIHVDSIRLLDIDMPEDLKRMMSRQASAEREKRATITKAEGDKEAAVNLAAAATTMAlsP 278 Myxococcus stipita...
ABC44202  132 ERERISQQIREIIDEATDPWGIEVQSVELKDIILAENMKRVIARQAEAERERRAVTIQAEGELEAAQNMADAASTLNdeE 211 Salinibacter ruber
CAN97523  130 HREEVAAKVRAQVEAVAAAWGLHVEMIGLQDIALPPQMQEVLAKGAIAERDRRYVVIKSEADVESAKNFAEAAGILArsP 209 Sorangium cellulos...
EKE21015  126 NRDTIAEKIRSIVDAATEAWGIEVHSVELKDVNLPEEMKRVIGKQAEAEREKRSVIIKAEGEVIAAENLAKAANTLSaaN 205 uncultured bacterium
AFM11870  129 ERQEIGDAIKKLVDNETDGWGLDVQAIKIQDIEVPDDLKRIMSRQAAAEREKRANIIKSEGDKEAAKNLADAAKMMErsK 208 Turneriella parva ...
ACL46907  187 EREQIQTRIMRNVETQIREWGLAVESVQLQDIELPEDLKRVMSRQASAEREKRATITKAEGDKLAAENLADAAETMArnP 266 Cyanothece sp. PCC...
EAR17142  120 KREEMGNNIKITVEQETAGWGIDILDVKIKDIQLPENMRRMMANQAEAERSRRARVILAQAEEQAAGTLLAAGKMIDqsP 199 Robiginitalea bifo...
BAE50616  151 QQEDLKQAIRRILDERTESWGVEVENVEIRSVDLDPNMIRAMGQEAEAERGRRARIITAQGEFEAATKLAEAATLMDgkP 230 Magnetospirillum m...
Feature 1                       
3BK6_A    161 MALQLRTLQTISDVAGDK 178 Pyrococcus horikoshii
EKY20631  209 GAINLRTLNTLERISTEP 226 Capnocytophaga sp. oral taxon 326 str. F0382
AGC41497  279 GAMQLRTLQSLDGLGSSP 296 Myxococcus stipitatus DSM 14675
ABC44202  212 GALHLRTLQTLNSLSSDD 229 Salinibacter ruber
CAN97523  210 GAMELRRFEALANLSQGN 227 Sorangium cellulosum 'So ce 56'
EKE21015  206 GALHLRTLSTINDVSSDQ 223 uncultured bacterium
AFM11870  209 GAMQLRTLQTLDGLGPTS 226 Turneriella parva DSM 21527
ACL46907  267 IALELRTLQTIDGLGASP 284 Cyanothece sp. PCC 7425
EAR17142  200 SAIKLRLYQTLSNIAAEK 217 Robiginitalea biformata HTCC2501
BAE50616  231 GAMLLRYLATLKDIAVEH 248 Magnetospirillum magneticum AMB-1

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