2DIV


Conserved Protein Domain Family
RRM1_SECp43
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cd12610: RRM1_SECp43 
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RNA recognition motif 1 (RRM1) found in tRNA selenocysteine-associated protein 1 (SECp43)
This subgroup corresponds to the RRM1 of SECp43, an RNA-binding protein associated specifically with eukaryotic selenocysteine tRNA [tRNA(Sec)]. It may play an adaptor role in the mechanism of selenocysteine insertion. SECp43 is located primarily in the nucleus and contains two N-terminal RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), and a C-terminal polar/acidic region.
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Statistics
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PSSM-Id: 410022
Aligned: 15 rows
Threshold Bit Score: 152.091
Created: 14-Dec-2011
Updated: 25-Oct-2021
Structure
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Program:
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2DIV_A        11 SLWMGDLEPYM-------------------------------------DENFISRAFATMGetvmSVKIIRNRLTGipaG 53  human
NP_001080588   3 SLWMGDLEPFM-------------------------------------DETFITLAFASMGetiaAVKIIRNRMSEglpG 45  African clawed ...
XP_002734335   4 SVWMGDLEPYM-------------------------------------DEAFVIEAFASVGekvlNVKIIRNKYTRipqG 46  Saccoglossus ko...
XP_002125303   4 SLWMGDLEPYM-------------------------------------DETFVNKAFLQVSqp-vSVKVIRRKDNGlpaG 45  Ciona intestinalis
NP_608837      7 QLWMGSLESYM-------------------------------------TENFIIAAFRKMGedptTVRLMRNKYTGepaG 49  fruit fly
EFX72729       8 SLWIGGLEPYM-------------------------------------TEEFLMRSFELMGekpeAIKVMRNKHTGlpaG 50  common water flea
EEN65663       3 SLWMGDLEPYM-------------------------------------DEPFIMNAFASMGepiiSVKLIKNRQTGgpaG 45  Florida lancelet
EDO32015       3 TLWMGDLDQFA-------------------------------------DEAFVASAFAAMGesvaSVKMIKNRITGgpaG 45  starlet sea ane...
EEC03010       5 TLWMGDIEPYM-------------------------------------DDAFLKQAFAQMGeaclSTKIIANKLTGlpvG 47  black-legged tick
EDV23390       3 TLWMGDSANDQvywmdspnvkgfmvydatmtlssgltfcrslqletymDETFIRNAFASVGrtvlSVKLIRNRVVGgpaG 82  Trichoplax adha...

2DIV_A        54 YCFVEFADlaTAEKCLHKINGKPLPGAtpaKRFKLNYATYS 94  human
NP_001080588  46 YCFVQFAEpeAAERCLLKLNGKPLPGAsynKRFKLNRAFYA 86  African clawed frog
XP_002734335  47 YCFVDFGSdeIAKAILRKYNGKPLPGSnnsKRFKLNFAAYG 87  Saccoglossus kowalevskii
XP_002125303  46 YCFIEFPSeaEAERVLKLVNGTTINGSnppKRFRLNRSQAG 86  Ciona intestinalis
NP_608837     50 YCFVNFISddHALDAMHKLNGKPIPGTnpiVRFRLNSASNS 90  fruit fly
EFX72729      51 FGFCQFRDekQAMEVLHKLNGKIIPYSqppSRFKLNHSTNT 91  common water flea
EEN65663      46 FCFVDFGDqqLAERALTRLSGKQLPGSytpKRFKLNYASYG 86  Florida lancelet
EDO32015      46 YCFVDFGDtgTAQKVMSKLNGLPIPGSnpiKRFKLNWATYA 86  starlet sea anemone
EEC03010      48 YGFMEFLDeaTAQRILLECDGKPIPGSnpvKKFKLNRASHS 88  black-legged tick
EDV23390      83 YCFVDFPDpqSAEDCLKQVNGLPLPGSnpqKRFKLNWATHG 123 Trichoplax adhaerens
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