2DWG,2CXF,2DWK


Conserved Protein Domain Family
RUN_RUFY3
?
cd17696: RUN_RUFY3 
Click on image for an interactive view with Cn3D
RUN domain found in RUN and FYVE domain-containing protein 3 (RUFY3) and similar proteins
RUFY3, also called Rap2-interacting protein x (RIPx or RPIPx), or single axon-regulated protein (singar), is an N-terminal RUN domain and a C-terminal FYVE domain containing protein predominantly expressed in the brain. It suppresses formation of surplus axons for neuronal polarity. Unlike other RUFY proteins, RUFY3 can associate with the GTP-bound active form of Rab5. This model represents the RUN domain of RUFY3.
Links
?
Statistics
?
PSSM-Id: 439058
Aligned: 9 rows
Threshold Bit Score: 278.803
Created: 10-Mar-2016
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
2DWG_A        11 ERMNLMNMAKLSIKGLIESALNLGRTLDSDYaPLQQFFVVMEHCLKHGLKAKKTFlgQNKSFWGPLELVEKLvPEAAEIT 90  house mouse
2CXF_A        11 ERXNLXNXAKLSIKGLIESALNLGRTLDSDYaPLQQFFVVXEHCLKHGLKAKKTFlgQNKSFWGPLELVEKLvPEAAEIT 90  house mouse
2DWK_A        11 ERXNLXNXAKLSIKGLIESALNLGRTLDSDYaPLQQFFVVXEHCLKHGLKAKKTFlgQNKSFWGPLELVEKLvPEAAEIT 90  house mouse
XP_006003787 109 ERLNLMNMAKLSIKGLIESALNLGRTLDSDYpPLQQFFVVMEHCLKHGLKTKKTFlvQNKSFWGPLELVEKLtPEAGEIT 188 coelacanth
NP_001087388  68 ERMNLMNMAKLSIKGLIESALNLGRTLDSDYaPLQQFFVVMEHCLKHGLKAKKTFlgQNKSFWGPLEFVEKLvPEAAEIT 147 African clawed ...
XP_007890157  88 ERLNLMNMAKLSIKGLIESALNLGRSLDSDYaPLQQFFVVMEHCLKHGLKAKKTFlgQNKSFWGPLELVEKLcPEAGEIT 167 elephant shark
Q7L099        68 ERMNLMNMAKLSIKGLIESALNLGRTLDSDYaPLQQFFVVMEHCLKHGLKAKKTFlgQNKSFWGPLELVEKLvPEAAEIT 147 human
KFV94260      68 ERMNLMNMAKLSIKGLIESALNLGRTLDSDYaPLQQFFVVMEHCLKHGLKAKKTFlgQNKSFWGPLELVEKLvPEAAEIT 147 sunbittern
AAH77105      68 ERLNLMNMAKLSIKGLIESALNLGRTLDSDYaPLQQFFVVMEHCLKHGLKSKKTFlgQNKSFWGPLELVEKLtPEAGEIT 147 zebrafish

2DWG_A        91 ASVKDLPGLkTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEVNALMMEEEGAIIAGLLVGLNVIDANFC 166 house mouse
2CXF_A        91 ASVKDLPGLkTPVGRGRAWLRLALXQKKLSEYXKALINKKELLSEFYEVNALXXEEEGAIIAGLLVGLNVIDANFC 166 house mouse
2DWK_A        91 ASVKDLPGLkTPVGRGRAWLRLALXQKKLSEYXKALINKKELLSEFYEVNALXXEEEGAIIAGLLVGLNVIDANFC 166 house mouse
XP_006003787 189 ASVKDLPGLkTPSGRGRAWLRLALMQKKLSDYMKALINRKDLLSEFYEPNALMMEEEGAVIAGLLVGLNVIDANLC 264 coelacanth
NP_001087388 148 ASVKDLPGLrTPVGRGRAWLRLALMQKKLSEYMKALINRKDLLSEFYEPNALMMEEEGAIISGLLVGLNVIDANFC 223 African clawed frog
XP_007890157 168 VSVKDLPGLkTPVGRGRAWLRLALMQKKLSDYMKALINRKDLMSEFYEANALMMEEEGAVIAGLLVGLNVIDVNLC 243 elephant shark
Q7L099       148 ASVKDLPGLkTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANFC 223 human
KFV94260     148 ASVKDLPGLkTPVGRGRAWLRLALMQKKLSEYMKALINRKDLLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANFC 223 sunbittern
AAH77105     148 ASVKDLPGLkTPLGRGRAWLRLALMQKKLSDYMKTIINRKDLLGEFYEPNALMMEEEGAVIAGLLVGLNVIDANLC 223 zebrafish
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap