2G1H,2H1Y


Conserved Protein Domain Family
fabD

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TIGR00128: fabD 
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malonyl CoA-acyl carrier protein transacylase
This enzyme of fatty acid biosynthesis transfers the malonyl moeity from coenzyme A to acyl-carrier protein. The seed alignment for this family of proteins contains a single member each from a number of bacterial species but also an additional pair of closely related, uncharacterized proteins from B. subtilis, one of which has a long C-terminal extension. [Fatty acid and phospholipid metabolism, Biosynthesis]
Statistics
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PSSM-Id: 272922
Aligned: 8 rows
Threshold Bit Score: 434.973
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2G1H_A         1 TQFAFVFPGQGSQTVGMLADMAASYPIVEETFAEASAALGYDLWALTQQGPAEELNKTWQTQPALLTASVALYRVWQQQ- 79  Escherichia col...
P71019         2 SKIAFLFPGQGSQFIGMGKELYEQVPAAKRLFDEADETLETKLSSLIFEGDAEELTLTYNAQPALLTTSIAVLEKFKES- 80  Bacillus subtil...
P73242         1 MKTAWVFPGQGSQAVGMGVDLLSTA-IAKEKYQQAEEILGWSVVEKCQ-GDEASLALTQNTQPCLYVIEAILADLLRDK- 77  Synechocystis s...
WP_003231821   1 -MITYVFPGQGSQKQGMGSGLFDEF---KELTDQADEILGYSIKRLCLENPYSNLNKTQFTQPALYVVNALSYLKKIRD- 75  Bacillus subtilis
P43712         2 KKFAMVFPGQGSQTVGMLADLATEYPIVIETFKQASDALGYDLWYLVQQGPAEELNKTWQTQPALLAASVAIYRVWKEK- 80  Haemophilus inf...
WP_003231811   1 -MITYVFPGQGSQQKGMGQGLFEQY---QHLTDQADQILGYSIEKLCTEKSYLDVNHTEYTQPALYVVNALSYLKRVEE- 75  Bacillus subtilis
WP_001199040   1 MQYALLFPGQGSQCIGMGKSFYESHTLAKELFERASNALKVDMKKTLFE-ENELLKESAYTQPAIYLVSYIAYQLLNKQv 79  Helicobacter py...
2H1Y_A        13 MQYALLFPGQGSQCIGMGKSFYEGHTLAKELFERASNALKVDMKKTLFE-ENELLKESAYTQPAIYLVSYIAYQLLNKQa 91  Helicobacter py...
2G1H_A        80 -Gg-KAPAMMAGHSLGEYSALVCAGVIDFADAVRLVEMRGKFMQEAVPEGTGAMAAIIGLDDASIAKACEEAAEg-QVVS 156 Escherichia col...
P71019        81 -G--ITPDFTAGHSLGEYSALVAAGALSFKDAVYTVRKRGEFMNEAVPAGEGAMAAILGMDAEALKQVTDKVTEegNLVQ 157 Bacillus subtil...
P73242        78 -G--FQPDYVAGHSLGEYSALYAAGVFDFATGLQLVKQRSEVMASAS---GGMMAALMKFDQTQLQQALTDNTE----VV 147 Synechocystis s...
WP_003231821  76 -Ee-VKPDFVAGHSLGEYNALFAAEAFDFETGLQLVRKRGELMSLIS---NGGMAAVMGLNEEQVAKALKEYHL--HDVD 148 Bacillus subtilis
P43712        81 -FpqLKPEVMAGHSLGEYSALVCAGVLDFQDAIKLVELRGKLMQQAVPEGTGAMYAIIGLDNEAIINACKQAEEg-EVVS 158 Haemophilus inf...
WP_003231811  76 -Tg-RKPDFAAGHSLGEYNALMAAGAFDFETGLRLVKKRGELMGRIT---GGGMAAVIGLSKEQVTAVLEEHRL--YDID 148 Bacillus subtilis
WP_001199040  80 nGg-LKPVFALGHSLGEVSAVSLSGALDFEKALKLTHQRGKMMQEACANKDASMMVVLGVSEESLLSLCQRTKN----VW 154 Helicobacter py...
2H1Y_A        92 nGg-LKPVFALGHSLGEVSAVSLSGALDFEKALKLTHQRGKMMQEACANKDASMMVVLGVSEESLLSLCQRTKN----VW 166 Helicobacter py...
2G1H_A       157 PVNFNSPGQVVIAGHKEAVERAGAACK-AA-GAKRALPLPVSVPSHCALMKPAADKLAVELAKITFNAPTVPVVNNVDVK 234 Escherichia col...
P71019       158 LANLNCPGQIVISGTAKGVELASELAK-EN-GAKRAIPLEVSGPFHSELMKPAAEKLKEVLDACDIKDADVPVISNVSAD 235 Bacillus subtil...
P73242       148 LANDNSPEQVVISGTVAGVEAILANVK-----ARRAVPLKVSGAFHSSFMAQPSQSFAQTLTACHFNDATVPVLSNVDPS 222 Synechocystis s...
WP_003231821 149 IANVNAPYQIVISGKKDEIEKAASLFE-TMtEVTMVLPLNVSGAFHSRYMNKAKEEFEEFLHAFYFSPPSIPVISNVYAK 227 Bacillus subtilis
P43712       159 AVNFNSPGQVVIAGAKAAVERAAALCK-EA-GAKRALPLAVSVPSHCALMKPAAEQLAVTLENIQINTPTISVLNNVDVK 236 Haemophilus inf...
WP_003231811 149 VANENTPQQIVISGPKKEIEKARAVFEnTK-DVKLFHPLNVSGAFHSRYMNEAKQVFKQYIDSFQFAPLAIPVISNVYAE 227 Bacillus subtilis
WP_001199040 155 CANFNGGMQVVLAGIKDDLKALEPTLK-EM-GAKRVVFLEMSVASHCPFLEPMTFKFQELLEKSLKDKFHFEIISNATNE 232 Helicobacter py...
2H1Y_A       167 CANFNGGMQVVLAGVKDDLKALEPTLK-EM-GAKRVVFLEMSVASHCPFLEPMIFKFQELLEKSLKDKFHFEIISNATNE 244 Helicobacter py...
2G1H_A       235 CETNGDAIRDALVRQLYNPVQWTKSVEYMAAQGVEHLYEVGPGKVLTGLTKRIVDTL 291 Escherichia coli K-12
P71019       236 VMTEKADIKEKLIEQLYSPVRFEESINKLIAEGVTTFIEIGPGKVLSGLVKKVNRRL 292 Bacillus subtilis subsp. subtilis str....
P73242       223 PTQNGDRLKEKLIQQMTGSVRWRETMVNLGEIGATDYWEVGPGKVLTGLCKRTCPDL 279 Synechocystis sp. PCC 6803 substr. Kazusa
WP_003231821 228 PYTY-EFMKQTLADQINHSVKWTDSISYLMKKGHMEFEEVGPGNVLTGLIHRIKKDA 283 Bacillus subtilis
P43712       237 AETEGTEIRTALVRQLYSPVRWTETVEKMAQDGVLVLAEVGPGKVLNGLTKRIVGDL 293 Haemophilus influenzae Rd KW20
WP_003231811 228 PYHQ-DRLKDTLSEQMDNTVKWTDSIRFLMGRGEMEFAEIGPGTVLTGLIHRIKNEA 283 Bacillus subtilis
WP_001199040 233 AYHNKAKAVELLSLQLTQPVRYQDCVKSNNDR-VDVFFELGCGSVLKGLNKRLSNkp 288 Helicobacter pylori
2H1Y_A       245 AYHNKAKAVELLSLQLTQPVRYQDCVKSNNDR-VDIFFELGCGSVLKGLNKRLSNkp 300 Helicobacter pylori SS1
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