5NJ5,1VL4


Conserved Protein Domain Family
TldD

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COG0312: TldD 
Zn-dependent protease PmbA/TldA or its inactivated homolog [General function prediction only]
Statistics
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PSSM-Id: 440081
Aligned: 790 rows
Threshold Bit Score: 161.516
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5NJ5_B        18 L-EEAVStALELASGKS-DGAEVAVSKTTGISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDlSPQAIARTVQA 95 
NP_924307      1 ---MDPQrLLELARKNGaEAAEVYLSQGLGRSANFEANRLKQVETGDEEGVALRVWRDGRPGLAVAHG--PVDDALLVEK 75 
WP_096720319   1 MkDQIVEqVIELARKKGi-KAEAYYVASRDTPIEFANNRLKSLETKASQGIALRVIADQKLGFASSTDl--TRLEDLVDA 77 
WP_099323880   1 M-DKIEEkILEQALKHTa-HVEVIYEEGETRSVSFENNKLKYINTKSVRGVGLRVIKDGRIGFSCTTDf--RKPEKLVAN 76 
WP_012954035   1 M-DIKPQkLIDLALRRGaSHAEVYQSKFKSSSVLFETNNLKSLESSDSQGIALRLWKEGAPGLAVAYG--EFDSDELADK 77 
WP_015132921   1 M---VVEqILDLAKQKGi-EAEVYYRSSRDTPIDFENNRLKSLETKATQGVALRVVVDGKLGFASSTDl--TRLEDVVDA 74 
WP_048164531   1 M-----EeLVRYGEKFf-DELEIAIYRKRDVSVNIELNELSLSSVRQRTVAVIRGIKDKRLGLAIIDSeNKEEIKKAIEQ 74 
WP_041619741   1 MtQSILEqVIDLAKQKGi-TAEAYYRASQDTPIEFANNRLKSLSTKASEGIALRIIADGRLGFASSTDl--TRLEELIDA 77 
WP_012548071   1 M---L-EkLIEIGKRYt-DEVEIYQINSFSSGVSFENGILKDIDSSIQSGISLRIIKDGKLGFSYTKNl--LDPEGLVKN 73 
WP_015220939   1 ---MQPEnLLDLVKKQGiKNAEVYQVESYSRPICFSANRLKQIESSQVSGVALRLWRDNKPGLALAYG--EFTADDLIAK 75 
5NJ5_B        96 ALDIAR----YTS-PDPc-aGVADKell----afDAp--DldlfhpaEVSP----DEAIELAARAEQAaLQADKRITNt- 158
NP_924307     76 AIALAQ----FG---QPeepELAGEpll----veSRp-hT-------PTPI----ERLIAWGEQTISLvRERYAEVl--- 129
WP_096720319  78 AIATAT----IG---DPvefDFSENits----ieSPv-dY-------QPPKt---EEFVKVGEDLIEQvHKYNPEIl--- 132
WP_099323880  77 ALESAE----FGQiAm---fDFPPQnnypqvtvfDRd-vI-------DFPI----EKCVRIGKEAIERaLAVD---SSye 134
WP_012954035  78 AIALSA----LN---NTesiELNHSytn----fqPNk-kD-------SISI----EQLIESGKNAINQlRDIHGEAv--- 131
WP_015132921  75 AIATAE----IG---DPvdfEFAKDfke----ivPEs-dY-------ELPEt---AKLVKIGEDLIEKvRDYNDEIl--- 129
WP_048164531  75 AYKMAK----LNS-RDEqwdSLPGPgkyakpkkiDTa-lK-------EVSP----EYFVELAKKGIKLaLEEDK-NIIv- 135
WP_041619741  78 AIATAT----IG---DPiefAFAENfhl----ttPDs-hY-------QPPTt---ASLVEVGENLIEKvHQYNPEIl--- 132
WP_012548071  74 AVDSLKgdirV---Ef----SFPERrelkvlntyDPe-iE-------NLTN----TKMVEEGQRISEIlSQAT---NTq- 130
WP_015220939  76 ALAVSD----LN---DPeeiFLNGTnnl----iySNddgN-------SKRFvdqdKKIIKEGGDAIASiLDLYPEAi--- 134
5NJ5_B       159 EGGSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVI-AEENGD-MERDYAYTIGr-AMSDL--Q-TPEWVGADCARRTLS 232
NP_924307    130 CGCTYSEEVGTVRLINSRGLDVSYASHHRSGYLGAEwV-RGED-FLQVYDGETVl---GDP----SPEAVAAPVLERLGW 200
WP_096720319 133 VDASFHVRTSEEKLATTTDVYTEQYGQSLSATLSGNlV-RGQD-FLQAYSYQVTr-DRTP-----DYQEILTKLLEKYQR 204
WP_099323880 135 CSAGIGKGHGKQRLLNSKGLDITIESTSLGIGIEIL-HIKGQS-LLSIGEGESSk-RLAT-----DLNKHVDKALNDLKL 206
WP_012954035 132 CNGEFIHSDYFTCLVNSLGLHCERNQSLVNYYLELElP-TEED-FLSVYDNKLAqgQ-GK---N-EIQQTVKTILQRLEW 204
WP_015132921 130 VSAGFHIRSGQTKLATTSGVYGERNSKVVSASLGGNlV-QGED-FLQAYGYDVAk-NAEP-----DYDKILATLIEKYTN 201
WP_048164531 136 AGGGGGVEWRESQILNSQGINVVQKGGGAYIYFELV-GMKEGNvTPGIFDLDAKl-SLN-L----DVEKVVENAAQKVKW 208
WP_041619741 133 VDVNFGIRSSQTKLATTTDVYTERSNHVVSASLSGNlV-RGED-FLQAYSYDVTs-DREP-----DYNQILDKLLQKYQR 204
WP_012548071 131 INVGVVKSVSEIRIINSKGVDYSTKNSSYMCYAAAM--------YPGSYSS-ISr-----IivDkKFKEFSKEDFEYITF 196
WP_015220939 135 VNLDVEWERETTTLINTQGLYCQQKDISQSASVGLElV-REED-FLGIYDGEYSh---GHI----DLSRIIESVLRRLEW 205
5NJ5_B       233 ----RLSPRKLSTMKAPVIFANEVATGLF-GHLVGAIAGGSVYRKSTFLLDSLGKQILPDWLTIEEHPHLLKGLASTPFD 307
NP_924307    201 ----SQENCPTRVGTVPVLFTAKATTVLL-GTVGAALNGRQVLQEASPWSQKRGEMVLSPLLSLSQDPQL--APYITPFD 273
WP_096720319 205 ----AQTTATITSGTYPVLFTPSALSSTMgRMFGTIFSGQSIVQKASPLTDKLGEKIVDSRITVYEDPHI--GVSACEFD 278
WP_099323880 207 ----AKKEVKLKTGDYPVVVTAKAMDIFL-STFEAGCNGKLLQKGASPLTNRLGEKIIDARVSIYDDATIDFADMSYPVD 281
WP_012954035 205 ----AKKTTLAPKGYIPVLFTPNGSSMLW-NTVSEALNSKFALDKTSPWSDKLQKQVMSNSLTLSQNPKY--KPYIVPFD 277
WP_015132921 202 ----AEKTAKISSGKYPVLFTPRAALSTIgGLFDTILSGQVVVQKASPLAGKLGEKLFGDRLTIYEDPSI--GVGARSFD 275
WP_048164531 209 ----AYKVEKSRTEEAKVIVEPWAISMLLsFALFPAFKGERLIKETTPLANKIGESVASELLTIYDDPFHELSLNPVIAD 284
WP_041619741 205 ----AEQTATISSGSFPVIFTPMAAAFTMgRLFETIFSGQVIAQKASPLVDKLGEKLFDERLTVIEDPTI--GVSACAFD 278
WP_012548071 197 lynnSKKEVKAKSGRMKVMFLPTTMYVLI-WRLIYGTNGKNVYERTTPLIDKIGTQIFDSSITIYNDPFNDSLPGARAFD 275
WP_015220939 206 ----AEKNVAVKTGKFPVLFTPNAVVTLW-DTVTEALNGKYILDKSSPWSESLGKVVISPCLTLKQQPDL--KPYDCPFD 278
5NJ5_B       308 SEGVRTERRDIIKDGILTQWLLTSYSARklGLKSTGHAG----------------GIHNWRIAGQGLSFEQMLKEMGTGL 371
NP_924307    274 DEGTPAIALEFVRAGRLETFYADRRIARrlGLRPGGNGLrsdlg------sypqpGLFNLVVAAGEHAFAELLSRMDDGI 347
WP_096720319 279 DEGVPTSKKHLIAQGVVEQFYWDRRWAArqGIESTGNGFrggis-------rpspSLANICIDPGSTSVEDLIADMESGI 351
WP_099323880 282 SEGVPARRTPLFEKGVLINYIFDLQTAGimKTQSTGNGNrgfss-------qpspGYSNIIVETGDMPFDSMVKDIKCGI 354
WP_012954035 278 DEGTSTQKLSLIKKGNLQQFYNNLANAKmlGMKSTGNGFrpnlk------syptpTLINLIVEPGEESFSNLIKKLDQCI 351
WP_015132921 276 DEGTPTSKKTFINKGIVEQFYWDRQWAArgHAEAKGNGFrggls-------rpgpDMVNFCMGAGNTPLTELIKGMKEGV 348
WP_048164531 285 DEGVPTRKNALIENGKFKGFIWDNYWAKiyGTESTGNGVrslat------ggisiGMHNTVIENGKKSLEDMIREIEHGY 358
WP_041619741 279 DEGTPTSKKVLIQAGEVKQFYWDRLWAArtGLQSTGNGFrggls-------rpnpDLVNLCFTPGTTSVADLIAGVEEGI 351
WP_012548071 276 DEGVESRVLPIVENGVLKNFYYDLYYGSkmGIGSTGNGYkvsdwggeiirvrptpALEHLYMKPGDKDFHEMIRLIDKGI 355
WP_015220939 279 DEGSMTQNLTLIEAGVLKNFYTDKKTASklGISNTGNGFrtglg------aypspDLVNLVISEGNKSFPEIVKNMDHGI 352
5NJ5_B       372 VVTELMGQ-GVSAITGDYSRGAA-GFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGNDIETr---S-NI-QCGSVLLPE 444
NP_924307    348 VVDQVLGG--GAGLSGEFSVNIDlGFRVKGGEIVGRIKDTMVAGNAYDALGRLAALGSERLWe---G-NV-FTPALLVES 420
WP_096720319 352 IVDQVLGAgQSNVLAGEFSVNIDlGYKVEQGKIVGRVKDTMVAGNIFEAFSNIVDLSDRPEWv---GsSA-YVPHILFAQ 427
WP_099323880 355 LVDQVLGGgQSNVLAGEFSVNIDlGYLIENGEIIGRVKDCMIAGNVFDLFNNIVAIGDRAEWh---G-ST-KVPPFYFKS 429
WP_012954035 352 IIDLALGK--KIDISGDFSINIElGYFVQDGLISGRVKNTVVTGNVYKVLENIIGIANDPCWi---N-SI-HTPSLLVEG 424
WP_015132921 349 IVDQVLGAgQSNQLAGEFSVNLDlGYKVENGEIVGRLKNTMVAGSIFEAFDHLIDLSDSCEWv---GgSA-LMPSMLFGK 424
WP_048164531 359 LINSFQGAhSSNPDNGNFAVVANpAFIIENGEVKGST-VFMMSGNIYDLLNQVYDISKEQKVipfmG-TV-VSPSIAFEN 435
WP_041619741 352 IIDQVLGAgQSNVLAGEFSVNLDlGYKIEKGEIVGRIKNTMVAGNIFEAFNHLIDLSSETELi---GgGS-TVPYLAFSQ 427
WP_012548071 356 IIAQALGAhSGNIPNGDFSIGLSpGLYVENGEIVGHVKDAMVAGNIYEVMKKVVAIENKNYV----G-NMgVFPSTIFED 430
WP_015220939 353 IVDQILGG--GADISGDFSFNIDlGYLVHNGKIQGRIKDTMLAGNVYQCLQKVNAIASDIVWs---G-AC-YTPSIVVDN 425
5NJ5_B       445 MKIAG 449
NP_924307    421 LAVTG 425
WP_096720319 428 LGVAA 432
WP_099323880 430 VNVAG 434
WP_012954035 425 LSIIN 429
WP_015132921 425 LGVAS 429
WP_048164531 436 VRIAG 440
WP_041619741 428 LGVAS 432
WP_012548071 431 VSVAI 435
WP_015220939 426 ISVVS 430
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