6O9L,6F41,3WWL,5FZ5


Conserved Protein Domain Family
TF_Zn_Ribbon

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pfam08271: TF_Zn_Ribbon 
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TFIIB zinc-binding
The transcription factor TFIIB contains a zinc-binding motif near the N-terminus. This domain is involved in the interaction with RNA pol II and TFIIF and plays a crucial role in selecting the transcription initiation site. The domain adopts a zinc ribbon like structure.
Statistics
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PSSM-Id: 400527
Aligned: 58 rows
Threshold Bit Score: 33.82
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6O9L_Q 128 KCPVCSS-TFtDleanqLFDPMTGTF-RCTFChTEVEEDESAMPKKDARTL 176 human
Q8ZSP6   4 QCPFCG--AK-Y-----EAPPGRGFY-VCPYC-GTVISEGRTFENVYIFKP 44  Pyrobaculum aerophilum
Q8ZYF7   2 VCPKCGS-RDiV-----LLPTN--EY-VCKKC-GYKWPMPQPDYMWIETEV 42  Pyrobaculum aerophilum
3WWL_A   4 TCPECGA-EL-R-----LENPELGELvVCEDC-GAELEVVGLDPLRLEPAP 46  Thermus thermophilus HB27
O34434   6 KCPNCGS-DM-------AFDSETGSL-SCSSC-GRQDNIESLPKENIAARF 46  Bacillus subtilis subsp. subtilis str. 168
5FZ5_W 123 MCPICLT-KYtQleavqLLNFDRTEF-LCSLCdEPLVEDDSGKKNKEKQDK 171 baker's yeast
A1RY32 114 VCPKCGT-RY-T-----VDEAENNNY-TCEVC-GEVLEPFDNTHRVEKLKR 155 Thermofilum pendens Hrk 5
Q58187 116 FCPNCNV-RF-T-----FEEAMDYGF-SCPGC-GNMLQEFDNSELIKDLEE 157 Methanocaldococcus jannaschii DSM 2661
O27705 117 VCVN-GH-YR-F-----TFDEATEENfTCPEC-GSKMEFMDNSEIIQEIKD 158 Methanothermobacter thermautotrophicus str. Delta H
O29501 119 ICPNMCVkVS-------YNDAMELNF-TCPRC-GAMLDYLDCSKAIEKIEE 160 Archaeoglobus fulgidus DSM 4304
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