1ML5


Conserved Protein Domain Family
prfB

?
TIGR00020: prfB 
Click on image for an interactive view with Cn3D
peptide chain release factor 2
In many but not all taxa, there is a conserved real translational frameshift at a TGA codon. RF-2 helps terminate translation at TGA codons and can therefore regulate its own production by readthrough when RF-2 is insufficient. There is a Pfam model called "RF-1" for the superfamily of RF-1, RF-2, mitochondrial, RF-H, etc. [Protein synthesis, Translation factors]
Statistics
?
PSSM-Id: 272858
Aligned: 7 rows
Threshold Bit Score: 571.333
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
1ML5_Z         3 EINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSG 82  Escherichia col...
O67695         2 MMVELKGKVEELRKRLEDVKKILSPEKLESELKELDQKMSEPNFWEDQEKAKQVIQRRKWVEETLNKLKNLEKSVKDLEE 81  Aquifex aeolicu...
P07012         3 EINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSG 82  Escherichia col...
P55999         2 DNYTYSELLKSLQNKCDNIALIIKPEKIKQELERIEKEQEDPNFWQDVLKARDTNKEKVRLNRLLETYQKTKNSLDESVE 81  Helicobacter py...
O32885         1 mEPDRQTDIAALDSTLTTVERVLDVEGLRTRIEKLEHEASDPKLWDDQVRAQRVTSELSHAQGELRRIEELRRRLDDLPV 80  Mycobacterium l...
WP_002659081   2 P---------------KTFGGSFDKNEIQAKIEKYEKEINQKNFWNDPKRAQEVIKAQSILKNKIDPWEELINKIKDLSD 66  Lyme disease sp...
P28367         2 ELSEIRAELENMASRLADFRGSLDLESKEARIAELDEQMADPEFWNDQQKAQTVINEANGLKDYVNSYKKLNESHEELQM 81  Bacillus subtil...
1ML5_Z        83 LLELAVEADDE------ETFNeAVAELDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWA 156 Escherichia col...
O67695        82 LVEITSEEDTE------TWAM-MDEEIKEVERTLRELELKTYLSGEMDAKNAYLTIQAGAGGTEACDWADMLFRMYKRWA 154 Aquifex aeolicu...
P07012        83 LLELAVEADDE------ETFNeAVAELDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWA 156 Escherichia col...
P55999        82 LFELAQNDNDE------VTLSlLYEEAPILENSVQKVEIEIMLSGENDASNAIITIQPGAGGTESQDWASILYRMYLRWA 155 Helicobacter py...
O32885        81 LYELAAEERAAaaasgmEAFAeADAELKALRVDIEATEVRTLLSGEYDEREALITIRSGAGGVDAADWAEMLMRMYIRWA 160 Mycobacterium l...
WP_002659081  67 LCEIAENEKDT------Ng---LEIEFNTLEKQYKDLLTISYFKEELDANNAFLTIHSGAGGTEACDWVAMLYRMYSRYA 137 Lyme disease sp...
P28367        82 THDLLKEEPDT------DLQLeLEKELKSLTKEFNEFELQLLLSEPYDKNNAILELHPGAGGTESQDWGSMLLRMYTRWG 155 Bacillus subtil...
1ML5_Z       157 ESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDD-IDIEIN 235 Escherichia col...
O67695       155 EKKGYEVELIDITPDDVAGIKSVTVLVKGPYAYGYLKGEQGVHRLVRISPFDANARRHTSFAAVSVMPQIDED-IKIEIK 233 Aquifex aeolicu...
P07012       157 ESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFSSAFVYPEVDDD-IDIEIN 235 Escherichia col...
P55999       156 ERRGFKSEILDYQDGEEAGIKGVAFIIKGENAYGYLKNENGVHRLVRISPFDANAKRHTSFASVQISPELDDD-IDIEID 234 Helicobacter py...
O32885       161 EQHKYGVEVLDTSYAEEAGVKSATFAVHAPFAYGTLASEQGTHRLVRISPFDNQSRRQTSFAEVEVLPVV-EItDHIDIP 239 Mycobacterium l...
WP_002659081 138 ERKKYKTELIDLLEAE-GGIKSVTIEIKGEYAYGLLKSEVGIHRLIRISPFDAAKKRHTSFASVFVDPVIDDK-IEITIK 215 Lyme disease sp...
P28367       156 ERRGFKVETLDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFVSCEVMPEFNDE-IDIDIR 234 Bacillus subtil...
1ML5_Z       236 PADLRIDVYRTSGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKS 315 Escherichia col...
O67695       234 PEDLKIETFRASGAGGQYVNKTDTAVRITHIPTGITVSCQQERSQYQNKRKALELLKAKLYQLEMKKLEEKKKQYEGEKT 313 Aquifex aeolicu...
P07012       236 PADLRIDVYRTSGAGGQHVNRTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKS 315 Escherichia col...
P55999       235 EKDVRYDYYRSSGAGGQHVNKTESAVRITHFPTGIVVQCQNDRSQHKNKASALKMLKSKLYELELEKQQSS--AKNEEKS 312 Helicobacter py...
O32885       240 EGDVRVDVYRSSGPGGQSVNTTDSAVRLTHVPTGLVVTCQNEKSQLQNKVSAMRVLQAKLLERKRLEERAELDALKG-RG 318 Mycobacterium l...
WP_002659081 216 PEDIRIDTYRASGAGGQHVNKTSSAVRITHIETGIVTQSQSDRSQHKNKDLAMKVLKSRLYEYYKSKEDEKNKSKQDTKK 295 Lyme disease sp...
P28367       235 TEDIKVDTYRASGAGGQHVNTTDSAVRITHLPTNVVVTCQTERSQIKNRERAMKMLKAKLYQRRIEEQQAELDEIRGEQK 314 Bacillus subtil...
1ML5_Z       316 DIGWGSQIRSYVLDD-SRIKDLRTGVETRNTQAVLDGSLDQFIEASLKAGL 365 Escherichia coli BW2952
O67695       314 DIGWGHQIRSYVFHPyKLIKDLRTGYETGNVEAVMDGEIDEFIESYLKWKA 364 Aquifex aeolicus VF5
P07012       316 DIGWGSQIRSYVLDD-SRIKDLRTGVETRNTQAVLDGSLDQFIEASLKAGL 365 Escherichia coli K-12
P55999       313 EIGWGHQIRSYVLAPyQQVKDARSNTAYSNVEAILDGDIDAILEGVLIAKA 363 Helicobacter pylori 26695
O32885       319 GSSWGNQIRSYVLHPyQMVKDLRNEYEVGNPTAVLDGDIDGFLEAGIRWRN 369 Mycobacterium leprae TN
WP_002659081 296 EISWGNQIRSYVFQPyNLVKDHRTKFENSNTTSVMDGNIDNFIEEYLKWKs 346 Lyme disease spirochete
P28367       315 EIGWGSQIRSYVFHPySMVKDHRTNTEMGNVQAVMDGDIDTFIDAYLRSKL 365 Bacillus subtilis subsp. subtilis str. 168
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap