Conserved Protein Domain Family
CCC1
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cd02435: CCC1 
CCC1
CCC1: This domain is present in the CCC1, an iron and manganese transporter of Saccharomyces cerevisiae. CCC1 is a transmembrane protein that is located in the vacuole and transfers the iron and manganese ions from the cytosol to the vacuole. This domain may be unique to certain fungi and plants.
Links
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Statistics
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PSSM-Id: 153126
Aligned: 12 rows
Threshold Bit Score: 239.531
Created: 13-Apr-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P47818    74 KDNRNGDNGSDNEKanlgff--qsvdpRVISDLIIGLSDGLTVPFALTAGLSSLgd-aKLVITGGFAELISGAISMGLGG 150 baker's yeast
EAA49335  75 STDSQASTASSSSRri---------saRIISDATIGLSDGLTVPFALTAGLSALdd-tRIVIYGGLAELIAGAISMGLGG 144 Magnaporthe grisea ...
EAA30629 669 KPSDSASSSSSSKKsnt--------fdGLFRDIILGFSDGLTVPFALTAGLSTLgs-tKLVIMGGLAELFSGMISMGLGA 739 Neurospora crassa
EAK82927  83 CPSQQHDPSFVCCRdvtaadertlidpDFARDCIVGLSDGLTVPFALTAGLSSTgs-tKLVVLAGLAELVSGAISMGIGG 161 Ustilago maydis 521
AAW46495  88 GGQCCKDLKGDDERhlv--------spEIVRDVVIGLSDGLTVPFALTAGLSSLgs-sSLVVTGGLAELCAGAISMGLGG 158 Cryptococcus neofor...
CAG81259  41 DTLSQGSGSSGSGNswv--------spRVVSDMIIGLSDGLTVPFALTAGLSSLgd-tKLVITGGMAELVAGAISMGLGG 111 Yarrowia lipolytica...
EAA59889 121 DVESTGSSNTRSRId-----------pRIVSDAILGLSDGLTVPFALSAGLSALgd-tKVVVLGGLAELAAGAISMGLGG 188 Aspergillus nidulan...
EAA61068  40 NGEIKPREAKESKLid----------gRVISDAIIGLSDGMTVPFALTAGLSALgd-tKVVVFGGFAELIAGAISMGLGG 108 Aspergillus nidulan...
EAA77873  11 FSSQQHSTNMKSIKtps--------lkRFFSDFTLGFSDGLTVPFALTAGLSSLgk-aDTVITGGLAELCAGSISMGIGG 81  Gibberella zeae PH-1
EAA78026  37 PCQSKHEECHVDYS-------------DILRDIIIGFSDGLTVPFALTAGLSSLgs-aKVVIIAGLAELFSGMISMGLGA 102 Gibberella zeae PH-1
CAE76010  15 DKAASHSHHHHPERhft--------sgEVVRDVIMGVSDGLTVPFALAAGLSGAsapsSLVLTAGLAEVAAGAISMGLGG 86  Japanese rice
AAD12695  14 EPEKQTLLDHHTEKhft--------agEIVRDIIIGVSDGLTVPFALAAGLSGAnassSIVLTAGIAEVAAGAISMGLGG 85  thale cress

P47818   151 YLGAKSESDyyh------aevKKEKRKFYDNSNLINREIEdil---------leiNPNFSDETIVSFIKdlq-------- 207 baker's yeast
EAA49335 145 YLGAKSEIAsy---------qETLSQTTHMINTDPEATLEavra--------vfaPYDVPKPTVDALAAhist------- 200 Magnaporthe grisea ...
EAA30629 740 YLAGVTERQhw---------eAEHARKAWEVSNLPQLEQSe-------------iLAILEDEYGVSRATaaalvqd---- 793 Neurospora crassa
EAK82927 162 FLSAQAELShf---------aYNLRSTQQKVERSCGTEVErq------------vHDILKGYGIAPDTSaqiaaeltake 220 Ustilago maydis 521
AAW46495 159 YLASQAELDhf---------hYLRRQTQARVLRSCSGEMEreihsilgplgvkepLSRLVAEDLRSVEDeiygssgaegs 229 Cryptococcus neofor...
CAG81259 112 YLAAKSENDy----------yKSECTKERAVLKTESSEGEsq------------iADILAQYNLSPETTasftk------ 163 Yarrowia lipolytica...
EAA59889 189 YVGAKSEAEsy---------qTTVRETTELIDSSPSETQAi--------------VYDIFASHGVPDDAiapina----- 240 Aspergillus nidulan...
EAA61068 109 YLVRESYHAt----------lKETTKQTLTSPATVSDTIHei-----------ftPYDLPDHLLAQLTThl--------- 158 Aspergillus nidulan...
EAA77873  82 YLAARDECLpghstildkedlRDHASSDEANETDCMVEQSekm---------qskLDDLVRHHLEPLDLpvstittildn 152 Gibberella zeae PH-1
EAA78026 103 YLAAVTERDay---------hSQAEKKEFAVHNRPADERTg--------------VYDVLQKYNVSRSSaaplvd----- 154 Gibberella zeae PH-1
CAE76010  87 YLAAKSEADhy---------qREMKREQEEIIAVPDTEAAe-------------iGEIMSQYGLEPHEYgpvvd------ 138 Japanese rice
AAD12695  86 YLAAKSEEDhy---------aREMKREQEEIVAVPETEAAe-------------vAEILAQYGIEPHEYspvvn------ 137 thale cress

P47818   208 ----------------------------------------------------------rtPELMVDFIIRYGRGLDEPAE 229 baker's yeast
EAA49335 201 ---------------------------------------------------------apdSKLLPDFLMHFHHREPEPES 223 Magnaporthe grisea ...
EAA30629 794 ------------------------------------------------------lcrkgnEENLVRFLMDLQVRMMEPDL 819 Neurospora crassa
EAK82927 221 qarrqaeqlaaiqqnrtsssrrklfgivsipsststvpahkriaaddqesqqlltdqdleNAGLTPFLLKLGEGLEPVST 300 Ustilago maydis 521
AAW46495 230 egvmsganvvsesg---------------------nkkwallnwrpkkveeedggmrgneEMGMTAFLLKFGEGMEEVPV 288 Cryptococcus neofor...
CAG81259 164 -------------------------------------------------------dlqknPTSMVDFIIRFGKGLEEPAE 188 Yarrowia lipolytica...
EAA59889 241 -------------------------------------------------------slhasRDRLREFLITFHHKESEPDC 265 Aspergillus nidulan...
EAA61068 159 ----------------------------------------------------------tsSPHLPSFLMTFHHTLPEPSG 180 Aspergillus nidulan...
EAA77873 153 -------------------------------------------------lqrepedlrhtISKLESFTDHTSLPSPQLTT 183 Gibberella zeae PH-1
EAA78026 155 -------------------------------------------------------elcknPTEWVRFMMDFELKLEEPNV 179 Gibberella zeae PH-1
CAE76010 139 -------------------------------------------------------glrrnPQAWLDFMMRFELGLEKPDP 163 Japanese rice
AAD12695 138 -------------------------------------------------------alrknPQAWLDFMMRFELGLEKPDP 162 thale cress

P47818   230 nrelISAVTIGGGYLLGGLVPLVPYFFVSdv---gTGLIYSIIvm---vVTLFWFGYVKTKLSMGSgssts--kkvteGV 301 baker's yeast
EAA49335 224 sralVSGLTIALGYFLGGLLPLLPYVIVSgpedlhRAWSISVAvm---aVALFSFGYAKTCFVTGWagqrcvrkglvgAV 300 Magnaporthe grisea ...
EAA30629 820 nrawVSAGVMGLSYFVGGLIPMLPYFFMEra---rEALWVSVVit---aLILLGFGFVKNWVTIRTreag-----vwgAV 888 Neurospora crassa
EAK82927 301 srlyVSALTIGLSYFLGGIIPLLPYMFVQea---sRALLLSVIit---gVILLVFGVVKQRVTGGEggfkg---yaygAI 371 Ustilago maydis 521
AAW46495 289 srlyISALTIGLSYFIGGLIPLIPYMATSta---eEGLLYSAIvt---sIILFIFGGFKTYFTGATggwyg---yaygAI 359 Cryptococcus neofor...
CAG81259 189 grefTSAMTIGLAYFFGGFIPLIPYFFTAhv---dDGLMWSVIvm---lITLFIFGCTKTVISLGSdvgrg--citwnGI 260 Yarrowia lipolytica...
EAA59889 266 nqawTSAITLALGYFIGGFIPLIPYFFLNqv---lIALYCSVAvm---aITLLVFGYIKTAVVRGWsgkdnilagvkgGI 339 Aspergillus nidulan...
EAA61068 181 sralTCALTIALSYFLGGFVPLLPYFFVGpdq-afLALKWSIAtm---aIALFVFGYGKTCFVSGWagsknikkgawgGL 256 Aspergillus nidulan...
EAA77873 184 sp-iISGLTISLGYAIGGIIPLLPYFFAStv---gMGLRLSSIlc---lMVLFTFGAGKSWILNPDrgnvv--tclveGL 254 Gibberella zeae PH-1
EAA78026 180 hrawISAVTMGLSYFIGGLIPMIPYFVMPrv---rEALLVSIGit---vAVLLVFGYVKNYVAIRNhrag-----vwgAV 248 Gibberella zeae PH-1
CAE76010 164 kraiQSALTIALSYVIGGLVPLLPYMFIS------TAQNAMLTsvgvtlVALLFFGYIKGRFTGNRpf--------lsAV 229 Japanese rice
AAD12695 163 kralQSAFTIAIAYVLGGFIPLLPYMLIPha---mDAVVASVVit---lFALFIFGYAKGHFTGSKpl---------rSA 227 thale cress

P47818   302 EMVVVGGVAAGAAWFFVKLL 321 baker's yeast
EAA49335 301 QMVVVGGAAAAAAMMLVKLF 320 Magnaporthe grisea 70-15
EAA30629 889 QTLIIGALAAGTSYAIVRLL 908 Neurospora crassa
EAK82927 372 STLAVGGVAAGASWLLVGLL 391 Ustilago maydis 521
AAW46495 360 STMIVGGCAAGAAFGLVKVL 379 Cryptococcus neoformans var. neoformans JEC21
CAG81259 261 QMTLIGGLAAGAAWGLVKLI 280 Yarrowia lipolytica CLIB99
EAA59889 340 QMVVVGAFAAGAAIGLVRLI 359 Aspergillus nidulans FGSC A4
EAA61068 257 QMVIVGGVAAGCAMGLVRGF 276 Aspergillus nidulans FGSC A4
EAA77873 255 QMLVLGALAAGAAVLCVTWV 274 Gibberella zeae PH-1
EAA78026 249 QTLVIGEAIALPRVIGIESS 268 Gibberella zeae PH-1
CAE76010 230 QTAIIGALASAAAYGMAKAV 249 Japanese rice
AAD12695 228 FETAFIGAIASAAAFCLAKV 247 thale cress
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