1DAP


Conserved Protein Domain Family
DAP-DH
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TIGR01921: DAP-DH 
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diaminopimelate dehydrogenase
This model represents the diaminopimelate dehydrogenase enzyme which provides an alternate (shortcut) route of lysine buiosynthesis in Corynebacterium, Bacterioides, Porphyromonas and scattered other species. The enzyme from Corynebacterium glutamicum has been crystallized and characterized.
Links
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Statistics
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PSSM-Id: 273877
Aligned: 4 rows
Threshold Bit Score: 493.69
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1DAP_A         1 MTNIRVAIVGYGNLGRSVEKLIAKQPDMDLVGIFSRR--ATLD--TKTPVFDVADVDKHADDVDVLFLCMGSATDIPEQA 76  Corynebacterium...
AAO77086       1 MKKVRAAIVGYGNIGHYVLEALQAAPDFEIAGVVRRAgaENKP--EELANYAVVKDIKELEGVEVAILCTPTRSVEKYAK 78  Bacteroides the...
WP_006769143   1 MSKIRAAIVGYGNLGKSVEKLIVQQPDMELVGIFSRRd--TLD--TDTPVFNVAETEKHTGDVDLLFLCMGSATDIPEQA 76  Corynebacterium...
BAB07799       1 MSAIRVGIVGYGNLGRGVEFAISQNPDMELVAVFTRRdpSTVSvaSNASVYLVDDAEKFQDDIDVMILCGGSATDLPEQG 80  Lysinibacillus ...

1DAP_A        77 PKFAQFACTVDTYDNHRDIPRHRQVMNEAATAAGNVALVSTGWDPGMFSINRVYAAAVLAEHQQHTFWGPGLSQGHSDAL 156 Corynebacterium...
AAO77086      79 EYLAMGINTVDSFDIHTGIVDLRRTLDATAKEHKAVSIISAGWDPGSDSIVRTMLEAIAPKGITYTNFGPGMSMGHTVAV 158 Bacteroides the...
WP_006769143  77 PGFAAFACTVDTYDNHRDIPRHRQVMDEAARAAGNVSVVATGWDPGMFSINRVYGAALLADHQQHTFWGPGLSQGHSDAL 156 Corynebacterium...
BAB07799      81 PHFAQWFNTIDSFDTHAKIPEFFDAVDAAAQKSGKVSVISVGWDPGLFSLNRVLGEAVLPVGTTYTFWGDGLSQGHSDAV 160 Lysinibacillus ...

1DAP_A       157 RRIPGVQKAVQYTLPsedalekarrgeagdlTGKQTHKRQCFVVA-DAADHERIENDIRTMpDYFVGYEVEVNFIDEATF 235 Corynebacterium...
AAO77086     159 KAIDGVKAALSMTIP----------------TGTGIHRRMVYIELkDGYKFEEVAAAIKAD-PYFVNDETHVKLVPSVDA 221 Bacteroides the...
WP_006769143 157 RRIDGVEKAVQYTLPsedalekarrgeaeglTGKQTHKRQCFVVApE-SEHERIENEIRTMaDYFVGYEVEVNFIDEATF 235 Corynebacterium...
BAB07799     161 RRIEGVKNAVQYTLPikdavervrngenpelTTREKHARECWVVLeEGADAPKVEQEIVTMpNYFDEYNTTVNFISEDEF 240 Lysinibacillus ...

1DAP_A       236 DSEHTgmpHGGHVITTGDTGG-FNHTVEYILKLDrNPDFTASSQIAFGRAAHRMkqqgQSGAFTVLEVAPYLLSPENLDD 314 Corynebacterium...
AAO77086     222 LLDMG---HGVNLTRKGVSGKtQNQLFEFNMRIN-NPALTAQVLVCVARASMKQ----QPGCYTMVEVPVIDLLPGDREE 293 Bacteroides the...
WP_006769143 236 DSEHTgmpHGGHVITTGDTGG-FHHTVEYTLKLDrNPDFTASSQIAFGRAAYRLkeagQAGAFTVLEVAPYLLSPTPLDD 314 Corynebacterium...
BAB07799     241 NANHTgmpHGGFVIRSGESGAnDKQILEFSLKLEsNPNFTSSVLVAYARAAHRLsqagEKGAKTVFDIPFGLLSPKSAAQ 320 Lysinibacillus ...

1DAP_A       315 LIARDV 320 Corynebacterium glutamicum ATCC 13032
AAO77086     294 WIGHLV 299 Bacteroides thetaiotaomicron VPI-5482
WP_006769143 315 LIARDV 320 Corynebacterium efficiens
BAB07799     321 LRKELL 326 Lysinibacillus sphaericus
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