1O8C,1TT7


Conserved Protein Domain Family
oxido_YhdH

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TIGR02823: oxido_YhdH 
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putative quinone oxidoreductase, YhdH/YhfP family
This model represents a subfamily of pfam00107 as defined by Pfam, a superfamily in which some members are zinc-binding medium-chain alcohol dehydrogenases while others are quinone oxidoreductases with no bound zinc. This subfamily includes proteins studied crystallographically for insight into function: YhdH from Escherichia coli and YhfP from Bacillus subtilis. Members bind NADPH or NAD, but not zinc. [Unknown function, Enzymes of unknown specificity]
Statistics
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PSSM-Id: 274315
Aligned: 30 rows
Threshold Bit Score: 457.405
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1O8C_A          23 QALLLEq--qDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMIPGIDFAGTVRTSEDPRFHA 100 Escherichia c...
BAD60465         4 RAMVAHe--sDSGIVLTRQELDENFLGQGAVTIKVHFSSANYKDALAITPGGGVVRKYPIIPGIDLTGEVVSSDSAEFAP 81  Nocardia farc...
jgi:Noc_2046     5 RGLRIDr--eKEGIQARLETLHLEDLSPGSVVIRAYYSSVNYKDALAATGKGKIMQRFPLVGGIDVSGVVESSTDPRCRP 82  Nitrosococcus...
AAF83261        40 TAFRIHr--dDAGHRAGLETVALELLTPGEVIVRALWSSVNYKDALAGTGRGRILHRFPLTGGIDVAGHVVASADPAFNE 117 Xylella fasti...
jgi:ReutB_3877   5 LAYRLHddgpDGRVAGRFTELRFDNLPPGDVLIRVAYSGINYKDALAAAGRNAIVRQYPRTGGIDLSGHVAASDDPRFRE 84  Ralstonia eut...
CAE35111        16 DAFQVRr---DTHISAGLARLKLDDLSPGDLVIRTAYAGINYKDALATTDYGKVIRKFPRVIGSDASGWVVASRDPAFRE 92  Bordetella br...
CAI10220         6 KAFLIDqd-eSRKVFSRMTTLAREQLDAGDVLIRVHYSSINYKDALAATGAGKIIRRFPCVGGIDLSGEVVESADARFRP 84  Aromatoleum a...
BAC12824         4 KAFVLYke-eD-RLHHKIENVNEDYWQEGDVWIDVAYSSINYKDAYVVKDGSLAEKS-PLIPGIDLAGIVRESNNPSFKK 80  Oceanobacillu...
AAG05222         5 KALWVTea-pHGVYETQVVERDTGDLPAGDVLIRVQYSSLNYKDALSASGNRGVTRKYPHTPGIDAAGVVAESSVAEFAA 83  Pseudomonas a...
jgi:Psyc_0011    8 KALVVEen-tNGTFSKSIQERSVSDLPENDLLIEVHYSSLNFKDAMSASGNKRITKQYPHTPGIDAAGVVVSDKSGTFTA 86  Psychrobacter...
1O8C_A         101 GQEVLLTGWGVGENHWGGLAEQARVKGDWLVAMpQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGV 180 Escherichia c...
BAD60465        82 GDQVVAHGYDIGVAHHGGFAEYARVPAEWVVKL-DGLSTRDAAAIGTAGFTAALSVQALLDRGLTPDDGAILVTGATGGV 160 Nocardia farc...
jgi:Noc_2046    83 GDKVLVTGYGLGSDHDGGYAGYVRVPADWVVPLpEGLSLYDAMALGTAGFTAALAIQRMEDNGQRPDRGLVLVTGATGGV 162 Nitrosococcus...
AAF83261       118 GDAVISTGCGLSETLDGGYSQYVRLKSHALLPLpAGLSLREAMVIGTAGFTAALALLRLTENHQTPALGPLVVTGATGGV 197 Xylella fasti...
jgi:ReutB_3877  85 GDAVVVHGFGIGVDHDGGHAQYARVRGDWVMRLpEGLSPLEASTIGVAGYTAALALHWMEHNAMSPEQGPVVVSGATGGV 164 Ralstonia eut...
CAE35111        93 GDEVAILGGGFGVDHDGGFSQYLRVPAGWAIRLpAGMTLRDAAALGIAGYTAALAVHLLQEAGCRPAHGEVLVNGATGAV 172 Bordetella br...
CAI10220        85 GDKVIATSFDIGVSHHGGYAEYARVPAEWVVPLpDGLDLFEAMALGTAGFTAALGIVRMEDNGLAPERGPVVVTGATGGV 164 Aromatoleum a...
BAC12824        81 GQEVIATSYRIGTGHHGGYAQLARVPSEWVIPLpDGLTLKEAMILGTAGLTAALSIQKLENNGLTPEQGPVVVPGATGGV 160 Oceanobacillu...
AAG05222        84 GDEVIVTGYDLGMNTAGGFGQYIRVPAAWVIKRpQGLSLREAMILGTAGLTAALCVEKLERSGLRPDHGSVLVTGASGGV 163 Pseudomonas a...
jgi:Psyc_0011   87 GQEVLVFGYDLGMNTDGGLSQMISIPADWALACpETLTLKEAMTYGTGGLTAALSVQKLEKMGAKPSDGPVAVTGATGGV 166 Psychrobacter...
1O8C_A         181 GSTAVALLHKLGYQVVAVSGRESTHEYLKSLGASRVLPRDEFA---ESRPLEKQVWAGAIDTVGDKVLAKVLAQMNYGGC 257 Escherichia c...
BAD60465       161 GSVAVDILSGLGFEVIASTGKTDAGDLLSEIGANEVIGRLPEDpdaKLRPLSKARWAGAVDSVGGRSLAYILSSIGYGGT 240 Nocardia farc...
jgi:Noc_2046   163 GNLAINMLAGLGYPVVALTGKREAVEDLKTLGASQILFRQELEm--gQRPLEKGQWGGAVDVVGGDMLSWLTRTVLPWGN 240 Nitrosococcus...
AAF83261       198 GMLALDIFSGAGFEVYAVSGKIQHTAFLHQIGATQVLPR-EVLl--tDKPLASAHYGGGLDNVGGPLLAGLVAQTVPHGN 274 Xylella fasti...
jgi:ReutB_3877 165 GSMAVDILSARGYMVHAMSGKSAEHAYLRSLGAGEILSPEVASq--pGKALEKARWAGAIDTVGGPVLAWMMRTMQPNGV 242 Ralstonia eut...
CAE35111       173 SSMGIEMLSGLGHAVTAVSAKADQHDYLRAVGAGAILAPADLAd--nGKPLEPARWAAALDALGGPHLDLIVRSLMPRGC 250 Bordetella br...
CAI10220       165 GGLSIDMLSRLGYHVVALTGKEAEDDYLRMLGAAEVRLRNTIDfd-nVRPLEATQWAGAVDNVGGKILHWILATMKQAGT 243 Aromatoleum a...
BAC12824       161 GSLAVNMLSNLGYEVIAGTGKEDKKEYLLQIGASEVVNRQDLQee-aPSSPQKTKWAGAVDPVGGNTLSYILNTLKRGGS 239 Oceanobacillu...
AAG05222       164 GSIAVELLAKLGYTVAAATGKLEQAEFLNRLGAKQILDRATVAd-gVDKPLLKEQWAGAVDTVGGDILFNVVKSLQYGGS 242 Pseudomonas a...
jgi:Psyc_0011  167 GSISIAILKQLGYEVIAFSGKPEQSEHLKDLGASEVRHRDTINe-iGNKPIGRELWANAIDTIGGDYLANLLKQTKAGGV 245 Psychrobacter...
1O8C_A         258 VAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPERRAQAWQRLVADLPESFYTQAAK-EISLSEAPNFAEAIINNQI 336 Escherichia c...
BAD60465       241 VAASGLTGGPDLPATVMPFILRGVALIGIDSVAYPIEKRRALWSRLTTDFRPRHLTQLEN-HAPVTDAERVLHAIKNGTH 319 Nocardia farc...
jgi:Noc_2046   241 IASIGLAGGSELHTTVMPFILRGVSLLGISSADCPMPLRQHIWQRLATDLRPRHLNQIVTgMVSLEELLPIFEGMLAGAH 320 Nitrosococcus...
AAF83261       275 IATVGLAASPTLNMTVMPFILRGVSLLGIGASGTVRTIREHIWGRLAGMWRPRHLEQICThEVGLDELPQVFEKMLAGAS 354 Xylella fasti...
jgi:ReutB_3877 243 IASVGNAGGPQLDTTVLPLILRGVRLLGINAN-SPMALREAVWAKLAADYRPRRLATIGQ-VIDFDALPDAMDRMLSRAT 320 Ralstonia eut...
CAE35111       251 VASYGNVTGNTLTTSVLPFILRGVRLIGVNLS-YYIDQETALWQRLAGELKPRRALEQVR-AIGLEEVAAQLRRMLDGQT 328 Bordetella br...
CAI10220       244 VASIGNAASFHLETTVFPFILRGVSLLGVDSGYMSFPTRERVWQRLASDLKPRHLAAVTR-TIAFDELPSAFDAFIRGEV 322 Aromatoleum a...
BAC12824       240 VATSGFTAGTDVQTTVFPFIGRGVNWLGIDSVTCSMEERTAAWHRLATDLKPTIFQNESIqEVTLEDLDQVFEAMLAGRT 319 Oceanobacillu...
AAG05222       243 VACCGLTAGAGFKASVLPFILRGVNLLGVDSVELPLVVKASMWDKLSLQWKLDNLEEVAR-EIALEELPGAINQILAGKL 321 Pseudomonas a...
jgi:Psyc_0011  246 VTSCGLAGGAEFSMTVMPFITRAVSLLGIDSVYIPLADKKAIWERVATDMKLPNLESYGE-EITLEQTPEYLDRFMSSQV 324 Psychrobacter...
1O8C_A         337 QGRTLVKV 344 Escherichia coli K-12
BAD60465       320 SRRTVLGV 327 Nocardia farcinica IFM 10152
jgi:Noc_2046   321 RGRTVVKI 328 Nitrosococcus oceani ATCC 19707
AAF83261       355 FGRTIVRI 362 Xylella fastidiosa 9a5c
jgi:ReutB_3877 321 RGRLVVRI 328 Ralstonia eutropha JMP134
CAE35111       329 TGRTVVDL 336 Bordetella bronchiseptica RB50
CAI10220       323 KGRTVVRI 330 Aromatoleum aromaticum EbN1
BAC12824       320 TGRTIVAL 327 Oceanobacillus iheyensis HTE831
AAG05222       322 VGRVLVNL 329 Pseudomonas aeruginosa PAO1
jgi:Psyc_0011  325 VGRYVVNV 332 Psychrobacter arcticus 273-4
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