Conserved Protein Domain Family
MATE_like_7

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cd13133: MATE_like_7 
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins
The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Statistics
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PSSM-Id: 240538
Aligned: 71 rows
Threshold Bit Score: 223.943
Created: 23-May-2012
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGJ49883   9 VGGYREVLTVSLPLVISMASNTLMQFTDRMFLASYSvDAIAAAMPAGMAAFLGIAFFMGTGGYANVFVAQYVGAGRpqRV 88  Desulfovibrio afric...
ADI14754   7 TGLTRNITLLAGPLILQNLSYTLLGVTDTFFVSRIStAAVGAVGLAGVLFFALMLLFRSTAASSVIFVGRAHGARDrrGV 86  Truepera radiovictr...
ABE59242   5 LSRFALLLRLALPIMGGMLSQSLLNLVDAALVGGLGeTALAGVGIGGYAMFMVTALLFGLSSGVQAQTARRHGEQVvaRR 84  Chromohalobacter sa...
EIJ41499  13 PPSIGEILRFALPLILGLMTNALMTLTDTVFMGWLGtAQLAAVPFASGIFLIGWVLMVGLMRSSIAFIARLYGAGDftKI 92  Beggiatoa alba B18LD
ABS24470  16 SAILRPLLALAWPMVVSRATQVVVGIADAVMVAHLGeAALAATTTGATNAFSIVILPMGIVFVVQSFASQLFGRGDlaGA 95  Anaeromyxobacter sp...
EHK62641   5 VRRQSRVMRLALPIMLGMLSQSMLNLVDAALVGHLGqEALAGVGIGGYTMFMMTALVFGLSSSVQSQTAQDLGAGKk-AV 83  Halomonas sp. GFAJ-1
ADV65697  15 AGTTRELLRLAWPLMFSNLAYTVVGFTDTLIMGRLGvTEVGAVGFASLCLLTLMLLFRGSLNTAATFTARAVGANH--PA 92  Deinococcus maricop...
ACO62424 152 QDRVEMVAKQALPVMGGMASQNVLNLADSAMVGRLGtACVAAVGISSTLNFQCQAALQGISSGVQAMSSRRIGEGKssVA 231 Micromonas sp. RCC299
EDM81783  17 DVSLRALLTLAWPVVLSRAALSVIGLCDALMTAPLGeDALAAATIGAMNTLTVMLLPMGVALIVQSFASQLHGQGDgaGA 96  Plesiocystis pacifi...
EAR59879   4 LERKKIILGLGLPIIAGMLSQSVLNLIDAALVGQLGeASLAGVGIGSYANFVVISLILGLSSAVQALVARTLGSGDreRS 83  Neptuniibacter caes...
EGJ49883  89 GAALWQGIWFSLLASALLALL---ALPAESLfs-laGHPEAVRKLEVTYFQILALGAGFSVLGSVMSCFYTGRGQTRVVM 164 Desulfovibrio afric...
ADI14754  87 GDAVWSVLWVVALLSLLAFALp--WVFTFLFrfaapAGSPEVLELGTRYLQIRAFEVPLAMFNALVWGFLVGRGDSRTPM 164 Truepera radiovictr...
ABE59242  85 AEALNAGLLIALCLAIPVSAAg--LWQAPRVia-wlNGDDAIQRVAVDYFRWRIAGLLPVALIFCFRGYWYGIQRTDVYL 161 Chromohalobacter sa...
EIJ41499  93 GHVLFHYQLLAILGLPLLLLY---VQLFPFFse-laQLSDVVAAYADTYLSILVWETAFTLLFILYASFYQALGNSAFPM 168 Beggiatoa alba B18LD
ABS24470  96 RRFGWYGLAVAAGAQVLGVLG---TLATPRAle-afAYAPDVRALMSGYLQIRLLSAGAVVGLEALSNYYGGLGDTRLPM 171 Anaeromyxobacter sp...
EHK62641  84 SRSLGAGLLLGALVGIPLSCIa--WWQAPALit-llSPADDVSRIAVEYFRWRVIGLTAIALTLCFRGYWNGLQHTHLYL 160 Halomonas sp. GFAJ-1
ADV65697  93 GVSRWASVFLTLALIGLPVALigpALVDGLFvl--lQPAPDITAVARTYAHIRVFEAPLVFLGTVALSIMVGLGNTRTPM 170 Deinococcus maricop...
ACO62424 232 AVPLNAALMLCLLFGIPMATWa--YTNAPMLvd-rlTADPEVIKHAVPYLQARLAAVPAVGINFAFRGFWNAAQQPQIYM 308 Micromonas sp. RCC299
EDM81783  97 RRYGWYGLILAGLAGVLGWAAi--PLVEPVLgl--mAYEPSVSALMGEYIELRLIAVATVIGYEAIGAWYGGVGNTRVQM 172 Plesiocystis pacifi...
EAR59879  84 VIPVYWGIILSVVIALPLSLLf--ISQSEQLtg-lmTDDLAVQDIAASYFDYRTAAMVAVGLNLSLRGWWNGNKQPVTYF 160 Neptuniibacter caes...
EGJ49883 165 LANVAGAALNVPLDYALINGtw--gmPELGIAGAGIATIVSAAFICLFIALLIFRQANEVDFgvr-------saWKPERE 235 Desulfovibrio afric...
ADI14754 165 LLAWLQVGLNIVLDWLLVLGnl--gfPAWGVAGAAVATVLANAAVTLLSAWILWRPDSHVRFrtr-------rvRPPRLA 235 Truepera radiovictr...
ABE59242 162 RIMLVTQVVNVAASAALIYGwa--glPRLGPAGAGAGTTLSLLVGVLMWAMLSRRHARGNGFl----------sRRPPLA 229 Chromohalobacter sa...
EIJ41499 169 RISLITLAINVVLDYALIFGkf--glPALGVAGSAYATVLSQAIAVLIMSVTLFNSPMCRRFcls-------iwQKVDFQ 239 Beggiatoa alba B18LD
ABS24470 172 RANLAAMVLNVAGNWLLIDGrl--glPALGVTGAAVASTLSTALAFAGLLAVFVREGRRTGT------------GTLRAR 237 Anaeromyxobacter sp...
EHK62641 161 RIIVIVHVFNVLVSAGLIYGia--glPKLGANGAGIGTTLSLLLGLVIWASVTVKKNRPWGY------------RLPSLG 226 Halomonas sp. GFAJ-1
ADV65697 171 QLAWMVVIVNAALALLFVFG------FGWGVAGAAWAALIAVGIQNALAVLLLHRLHARAYGpf--------rlTRPTRD 236 Deinococcus maricop...
ACO62424 309 NTLLIMHAVNIGLSLALIFGvpalgvPAMGVVGAGIGTSFSVWVGSALYLRMGFQRAKHMGFg----------cCFPSAN 378 Micromonas sp. RCC299
EDM81783 173 VGSLLMMVVNVALNYLLIEGhl--gaPALGVRGAAIASVVATSLGCAVMVGSFSFGLWTPDAatggrgepgeglGGLSWQ 250 Plesiocystis pacifi...
EAR59879 161 KVLLFTHLLNVVVSYCLIFGel--glPRLGAPGAGLGSAIALFAGAFFNFWLLRKELKPTRRli---------tSLIRDY 229 Neptuniibacter caes...
EGJ49883 236 LFGRLMRYGLPGGTQFCMdILAITFFIFMVGR-LGRAELAATNIVfNISMLAFMPMIGVHVAVSTLVGQAIGRGRPEDGA 314 Desulfovibrio afric...
ADI14754 236 ELRRVLATSLPLGVGDFVdVASFTVFFALIGR-LGTEILAANNIAlQFMSLSFTLGIAVAQASSSLVAQALGAEDPKRAE 314 Truepera radiovictr...
ABE59242 230 VYVRTLRLAAPHSFQQFCfAAGYAVLFWILGH-VSGASVAVGHVLvNLSLFLILPGVGLGLAAMSLVGQSLGQASPEDAH 308 Chromohalobacter sa...
EIJ41499 240 LIKQILRIGIPQGLGDFVeLIAWVGLSVIAGR-VGETALAANNIGmQFTLVLFLPGLALGIAAASYMGRFLGENRPVLAR 318 Beggiatoa alba B18LD
ABS24470 238 ELGRLLRFGVPSGVNWFFeVLAFVFFVNVVFVeLGTTSLAALMAIlQVNTVAFMPAWALASAGAILVGQAIGASHADRVP 317 Anaeromyxobacter sp...
EHK62641 227 AVRSTLYLAFPHSMQQLWfAAGYVVLFWLLGR-IGTESVAVGHVLvNLSLLLILPGVGVGIAAMSLVGEALGRDDQQAAH 305 Halomonas sp. GFAJ-1
ADV65697 237 ELRSFARVGLPAGTTELGeVGAFTVFQGVISR-LGPAELAASQIAnQFASLGFLPAFALASATGSLLSRALGAGRPDIAR 315 Deinococcus maricop...
ACO62424 379 DFKVLLKQAAPTSGTNLLfATGMAAMYWIVGQ-LGTAETAAVNVLiNLMLTLVLPCMGMGLAAGALSGRALGRGDVDDAT 457 Micromonas sp. RCC299
EDM81783 251 EFGRMVRFGLPNGINYLLeFAAFMIFVDFIVAdIDTVTVAALMVViQVNSVSFMPAFGLASAGAILTGQAIGADQRDAVP 330 Plesiocystis pacifi...
EAR59879 230 SLIRFFRLALPHSLQQFLlALAICTLIWIIGQ-LGTHEQAIAHVLiNLSLFLILPAVGFGVASTSLVSHAMGEKNLQAAS 308 Neptuniibacter caes...
EGJ49883 315 RATTSAVHISLLYMSLFGLVFLFLPEALLDLFRpad----asDAEFAAiveAGIVLLRFVTLYnCFDAIGIIYSGAIRGA 390 Desulfovibrio afric...
ADI14754 315 RVGYRAMGLGMALMGLVGLGYLVAPERLMGTFSg--------DPRVIE---AGTAILQLVALYqIFDAAAIVLGGALNGA 383 Truepera radiovictr...
ABE59242 309 RWGWDAVRLAWLCLALLALPMAWAPEWLLGMFLh--------DPALID---MGRLPLRLTAAMiVLDAAAIVLAQALLGA 377 Chromohalobacter sa...
EIJ41499 319 LTTYKILWIGCSYMGLLGIPLWFFGADIARLFTd--------DAAVIA---EAAAMFKVMAIYqLFDCLGIITRTALSGA 387 Beggiatoa alba B18LD
ABS24470 318 RLVAVTFAVSAAWQLFVGALYVLAPEAILAPFAtga----gpGSAFVA---IGRRVLLLAAAWqLFDAAAMSLGEALRAA 390 Anaeromyxobacter sp...
EHK62641 306 RWGIDALSVAGMLLTVLALPMLLFPTTVLAIFFt--------DHGLIQ---LGTLPLQITGFMiVLDAAALVLAQALMGA 374 Halomonas sp. GFAJ-1
ADV65697 316 RVGWRGALLAAALMGALGLLFLLVPRQLIGLFNh--------DTQVLA---LGTSVLAVMAAYqLLDGLAIVLGGALGGA 384 Deinococcus maricop...
ACO62424 458 QWPWDVAKLTAALMFGVGLIAVLIPEVLLKVFLt--------NEDAIR---VATWPLRFTGITvAGDALSLTMQNALLGV 526 Micromonas sp. RCC299
EDM81783 331 GVLRRTMTATAVWQVSVGVIYVLAPATIMAAFAardgegastSTPEIVe--VGALLLALSAAWqLFDAVAMSFAETLRAA 408 Plesiocystis pacifi...
EAR59879 309 RWGWDVVKTAFTTVLILSLPLLFIPESVLKIFLh--------SEEIIE---QAKLPLRLTALAiCLDAATIVFTQALLGV 377 Neptuniibacter caes...
EGJ49883 391 GDTmfVMKAIAVVALLAMFLPVTILSTIy-qGNLYQLWACATLYISALSLAFALRYRQGAW 450 Desulfovibrio africanus str. Walvis Bay
ADI14754 384 GDTt-YTMLARLVCAWGIFLPLAYLFAFplgGGVRGAWAGAMAYLVALALAYLVRFRSGRW 443 Truepera radiovictrix DSM 17093
ABE59242 378 GANr-TVMKVTLLLQWVAFLPLAWWVGVslgHGLAGVWWVQLGYRCMNSLWFTTIWQRRHW 437 Chromohalobacter salexigens DSM 3043
EIJ41499 388 GDTf-IPSILLVLCIVAILFPAAISLSTfiqPPLVGIWLGAFVYMIVLAGFMLYRYRSNRW 447 Beggiatoa alba B18LD
ABS24470 391 GDTa-FVMWMRVTLGWAVFVPGTWISVRelgAGEVVAVGWLVLWLALLALALLLRFRSGAW 450 Anaeromyxobacter sp. Fw109-5
EHK62641 375 GAQr-TVMLLTLSMQWLVFLPLAWWVGIgmeYGLLGVWLVQLFYRLLNSGSFLWVWQRRRW 434 Halomonas sp. GFAJ-1
ADV65697 385 GDTr-FRLVVTLTGAWLVMVLSATYLAPr--YGVTGAWTGALAYIALAAIAYALRFASGRW 442 Deinococcus maricopensis DSM 21211
ACO62424 527 GDAa-RVAMVSIGTQWLLFLPVAYFGVTrfgFDLNWMWGLYVGQRVLQAVIYAAMWRDGKW 586 Micromonas sp. RCC299
EDM81783 409 GDTa-WPMWARLSIAWFVFLPVGYAGVVwldGGGVAAVLSIVLYIALLALALGWRFRGGAW 468 Plesiocystis pacifica SIR-1
EAR59879 378 GASr-SVLLISTLGQWCFFLPLAWLFGPffgFGLIGIWLVQVVYRFLSSIMFIRIWSQRSW 437 Neptuniibacter caesariensis
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