2BB6


Conserved Protein Domain Family
Cobalamin_bind

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pfam01122: Cobalamin_bind 
Eukaryotic cobalamin-binding protein
Statistics
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PSSM-Id: 460073
Aligned: 42 rows
Threshold Bit Score: 332.294
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2BB6_D         1 NIC---EITEVDSTLVERLGQRLLPWMDRLSQEqlNPSIYVGLRLSSLQAGAKEAHYLHSLKLSYQQSLlRPASNkddnd 77  cattle
NP_001116703  17 KPC-----ASDHETLLQSLNKQLLRSVDTQDNLp-NPSVHIALRLSTQHNLDKENQYLNRLKKEFHEDIeKSLRNgel-- 88 
XP_005473431  19 IPC---DTDGSNTELLLSLNKNLLRSLESQEGLp-NPSIHLALRLSKKHNLAKESEYLNRLKNELHNDIqSSLSNsqp-- 92 
1_pfamImport  17 KPC---ATEGSNREFHLSLNKNLLRSLETQEGLp-NPSVHLALRLSDNHNPPKESEHLNRLKNLLHNDIqSSLSNsqs-- 90 
XP_004072417  17 KALnlhDTDGNYRELLLSLNKQLLHSLETQEGLp-NPSVHLALRLSNYHNHVKEDEHLNKLKNDLHNEIqSSLRNnqp-- 93 
XP_005993347  20 TAC---DLPAEHTKLFLSLNKKLLRSLEDDSRVp-NPSIYLGLRLSGTHNLQMEKRYLQRLQQELEPSLgRDKSTlesk- 94 
XP_001380461  19 QFC---EIPPANSNLVVRVTQQLLGWMDRQSPLelNPSIYVGLRLSKQPSQDQDDFYLNSLMIHYQQSFsSLALEhqpk- 94 
O88968        19 EFC---VIPRIDSQLVEKLGQRLLPWMDRLSSEqlNPSVFVGLRLSSMQAGTKEDLYLHSLKIHYQQCLlRSTSSddnss 95  house mouse
XP_002719754  19 EIC---GVPKVDSQLVEKLGQRLLPWMDWLSLEhlNPSIYVGLRLSSLQAGTKEDLYLHSLKLSYQQCLlGSASGddtsd 95 
XP_008117996  20 QLC---EIPPGNGHRVASLSAELLSLAHDATRAp-DPSLYLGLRLSERHSLEKERLYLERLQGVYQPNDsNDQVApryqe 95 
2BB6_D        78 seakpsmGQLALYLLALrANCEFIGG------RKGDRLVSQLKRFLEDEKRAIGHNHQGHpRTSYYQYSLGILALCVHQK 151 cattle
NP_001116703  89 -----vvGRLALYILALrSSCHDLSLhln-hnEKNEFLLTHLKKEMEEEKQNIAFSH--RpKTNYYQYSLGILALCVSGV 160
XP_005473431  93 -----vtGVLALYSLALkSSCYDLNTvsftvnERSQTLLTHLKNQMELEKEHF--TH--RpLTNYYQYSLGVLALCVSGI 163
1_pfamImport  91 -----vvGLLALYTLALkSSCYDLNTvtftvsEKSETLLTHLKKQMDDEKDNIAFSH--RpLTNYYQYSLGVLALCVSGI 163
XP_004072417  94 -----vtGLLALYSLALkSSCYDLNTvvfmvtEKSETLLAQLKKVMEQEKEHVAFSH--RpLTNYYQYSLGVLALCVNGI 166
XP_005993347  95 ----pttGLLSLYLLSLrASCLDMNT------AEANGLITQLKHKLHHEKEHIVQHK--RpQSNYYQYSLGILALCVNGK 162
XP_001380461  95 ----psmGQLALYLLAVrGGCRDIDT------RKGSMLVTQLKYYLEEEKHRIGHNHEGYpLTSYYQYSLSILALCIHNK 164
O88968        96 cqpklsgGSLALYLLALrANCEFFGS------RKGDRLISQLKWFLEDEKKAIGHNHEGHpNTNYYQYGLSILALCVHQK 169 house mouse
XP_002719754  96 cqakpsmGQLALYLLALrANCEFVGG------RKGDRLVSQLKWFLEEEKRNIGHDHKGHpHTSYYQYGLSILALCVHQK 169
XP_008117996  96 ---qpgtGRLALYLLALrGACHDMDT------PEAHRLVTQLKLHLHKEKAEIGPESLGRpLSNYYQYGLGLLALCVHGK 166
2BB6_D       152 RVHDSVVGKLlYAVEHKPHLLQDH---VSVDTMAMAGMAFSCLELs--NLNPKQRNRINLALKRVQEKILKAQTPeGYFG 226 cattle
NP_001116703 161 RVSTHVSHKLiHAVEHGQIKHGES---LCIDSHAMAGMALQCLKNe--GISVKDEAELDKALATIKQKLVDSKRAdGHMG 235
XP_005473431 164 RVNNHVTNKLiKAAEHEQFTHGES---ESVDTYAMAGMALQCVKDt--GSHMQNAAGLNTALSKIKGKLLASRRTdGHIG 238
1_pfamImport 164 RVNNHVSNKLiKAVEMEHFKHGDEstgLALDTNAMAGMALQCVKDa--GSHVQNAAELDAALSQIKQKLLASRRDdGHIG 241
XP_004072417 167 RVNNHVTHKLiKAVEHENFKHGDV---ESIDTYAVAGMALQCVKDs--GSYTHNAAEIDLALSKIKHKLLASRRTdGHMG 241
XP_005993347 163 EVEHHVVRKLiHAESHEGFLHGDA---LSIDTEAMAGLALRCLELsesRYNEELKSKIKVAIQSVRQKILQSQDKeGLFG 239
XP_001380461 165 KVPGHVVEKLlHAAEHNLFLHGSQ---FSVDTAAMASLTFSCLKDs--GLNPGLASRISRASKHLRNKILEEETPeGYFG 239
O88968       170 RLHDSVVGKLlYAVEHDYFTYQGH---VSVDTEAMAGLALTCLERf--NFNSDLRPRITMAIETVREKILKSQAPeGYFG 244 house mouse
XP_002719754 170 RVPDNVVGKLlYAVEHDQHLHRGH---FSVDTVAMAGLAFTCLERl--NLNPDQKQRISTAIGTAREKILGAQTPeGHFG 244
XP_008117996 167 MVDGHVIHKLlHAEEHGRLGIHGK---LSVDTEAMAGLAFACLQRa-aFYPPELRAKLRQSVERVKGKILEGQTPaGAFG 242
2BB6_D       227 NVYSTPLALQLLMGSLRPSVElGTACLKAKAALQASLQHKTFQNPLMISQLLPVLNQKSYVDLISPDCQAPR--ALLEPA 304 cattle
NP_001116703 236 NEFSTGLAVQALLAMGVEMEE----CGTAIEALRGDIRKGTYHNPMAASQVLPALYQQSYLHLKSKECRSEDdtLTAD-- 309
XP_005473431 239 NEFSTGLAVQALLAMGSEVAE----CAASMEAMRTAARSNTYHNPMAISQTLPALQQTSYVAVKSKECLTEDntLVLEPL 314
1_pfamImport 242 NEFSTGLAVQALIAMGSRVAE----CAASMEAMRTDARSNTYNNPMALSQILPALQHKSYLSIKSKECLNEDdtLVVEPI 317
XP_004072417 242 NEFSTGLAVQALIAMGSEESE----YSISMAAMRTAARNNIYHNPMAISQTLPALQKQSYLKVKGKECLNEDntLVLDMT 317
XP_005993347 240 NVFSTPVAVQALVAMEMTENR--DQCSKALGALVDAVRNGIFHNPMAMSTLNPVFHQKTYLDIRTMDCIAEEdgLTLGPK 317
XP_001380461 240 NIYSSPLALQALMAAPLPESE--QACLRVGGALLKGLQAGAFQNPIPLSQLLPVLHHKTYLDLIQLDCNDKRvlDPLEED 317
O88968       245 NIYSTPLALQMLMTSPASGVGlGTACIKAGTSLLLSLQDGAFQNPLMISQLLPILNHKTYLDLIFPDCQASR--VMLVPA 322 house mouse
XP_002719754 245 NVYSTPLALQLLMASPVSGVQlGAACLKARAALLASLQDGAFQNVVTISQLLPVLNRKTYVDLIFPDCQAPR--VTLVPA 322
XP_008117996 243 NIYSSPLAAQFLLAVGQSRKE--PECPKGMASLLRHLEQGDSPDVLFKSQLLPVLNGKSYLDIASVECHAETdgLALGTP 320
2BB6_D       305 L--ETPPQAK 312 cattle
NP_001116703 310 ---VESASEV 316
XP_005473431 315 DptVVPPNQV 324
1_pfamImport 318 DpvVDSGSKS 327
XP_004072417 318 DpvVPLPSDT 327
XP_005993347 318 RpgGDVATKT 327
XP_001380461 318 A--TTPQTQE 325
O88968       323 V--EDPVHIS 330 house mouse
XP_002719754 323 S--EAPSLSE 330
XP_008117996 321 Sp-TLPQPTR 329
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