Conserved Protein Domain Family
phage_ICD_like

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NF033153: phage_ICD_like 
host cell division inhibitor Icd domain
Icd from temperate phage P1 inhibits cell division in its host. Homologous sequence is found in many other proteins, often as the C-terminal region of what appears to be a much larger protein. Putative phage proteins that contain this domain may be designated "host cell division inhibitor Icd-like protein". See PMID: 8491703 for a description of Icd. Many proteins with this domain also have the Ash domain described by PF10554, which also occurs in phage.
Statistics
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PSSM-Id: 467967
Aligned: 78 rows
Threshold Bit Score: 39.0619
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_005559907  48 YQFIFAAIRrTDLTNqiqkIRINADTEREARAMLA-RDFMLVLAGRINP 95  Aggregatibacter actinomycetemcomitans
WP_019077821  14 YIWRFLALSaIGrn----vIHITATTEREAREQSPaG-CVMVFAGRLPV 57  Enterobacteriaceae
WP_005971436  13 FIWRFLALGmSSrr----iIRIVATTEHEAREKSPaG-CVMVFAGRLPV 56  Pectobacterium wasabiae
WP_014913824  13 FQYRFLALGtSSqr----vVHIIAATERQARKHSPdG-HVMVFAGRLPV 56  Pectobacterium
WP_013814368 178 YHFRFLALDrANRKAapccISVDASSECEARRVLA-PYFILSLAARLPV 225 Serratia
WP_001411725  13 YQYRFMALDrADRQAkpckIIVEATSEHEARKVLA-PHYILSLSAVLPV 60  Escherichia coli
WP_005968179  13 FTWRFLALNrHDKKAkpcrLSVEAATEREARLILA-PHFILSFAARLPL 60  Pectobacterium
WP_009638479  13 FQYRFLAIDrANRKAtpcrLTVEAHTEHEARLILC-AHFILSLAARLPT 60  Serratia sp. M24T3
WP_012540059   9 FIWLFLATPkKH-DCspivLRTQADSEEAARNTF--PGWDLIFAAKIRT 54  Klebsiella variicola
WP_000775005  13 FTWLFLGTPrGH-SClpivLRTIADTEDTARAKF--CGWDLTFAAKIRT 58  Enterobacteriaceae
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