Conserved Protein Domain Family
T7SS_EccE

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TIGR03923: T7SS_EccE 
type VII secretion protein EccE
This model represents the transmembrane protein EccB of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccE1, EccE2, etc. This model represents a conserved core region, and many members have 200 or more additional C-terminal residues. [Protein fate, Protein and peptide secretion and trafficking]
Statistics
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PSSM-Id: 274857
Aligned: 21 rows
Threshold Bit Score: 126.403
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_010983978  55 FRLQRIVLLEIAAAVLLAg-WVIDPLAlv---pAAVVAVVLVLLAFVRRRGRSLPEWLGTARALKARQRRAastpiPPGT 130 Streptomyces av...
WP_003940702  13 HRISTREFVPAQIFGIGA--GGIAMASgldwfwGLAIGCVVAGSMLLHVGGWSVMSWIVRYFRYLHRKDVD-----RSTI 85  Rhodococcus ery...
WP_005114610   4 ATMPIQIMVISQLLVLAA--VLISLLFgwpwwaALLIAIVSLALVLGRWGGQTVRHWAVTGFKYLTGRTYR--------- 72  Mycobacterium a...
WP_011207376  14 GRISMPNLLAAQVIGLLA--GIVALLAgldavvALAVAVVAMLLPLIPVAKRTVLDWIVTWWRFRTRREYE-----LGDT 86  Nocardia farcinica
WP_011726653  15 HGIWAATLIPACIAICMH--Fdll-------wlGITLGALIALFSVLTIRGLRITGWVRAIFSWRRRHRST-----PDIA 80  Mycobacterium s...
WP_015294706  13 HTLLASALAPPCIIAFLEtry---------wwvGIALASLGVIVAMVTFYGRRITGWVAAVYAWLRRRRRP-----PDSS 78  Mycobacterium c...
WP_011207355  36 hiplrymiplalfaalaawvatafdapaaviaivvavvliagAAPVRRRHPRNVVGMIARAIAFRRRRVRP-----DKLP 110 Nocardia farcinica
WP_011896186  26 WTLWRTITVLVVSVGWVA----ATVGRlhpvwvALPV-VVLALLAFSTVYHVTLTRWVQRRWTWWRRRRAA-----TP-P 94  Mycobacterium g...
WP_011767971   6 vglragtpvvvalevvalvaFIGLPPArfgwwpAAVITAVALLLLVPTVHRRNVPGWLAAVRRWRRSRRGK-----YPAA 80  Mycobacterium s...
WP_031712046  10 PRSARRVAGVWTVFVLASagWALGGQLga-----vMAVVVGVALVFVQWWGQ--PAWSWAVLGLRGRR--------PVKW 74  Mycobacterium t...
WP_010983978 131 EPGlapaVecdpslrtyaygGRD-RRPVGIIGDGTFVTAVLQVEADATALRAER------SRQPLPLGLVRDALEV-DGI 202 Streptomyces av...
WP_003940702  86 VSF----H------------TPS-EQSIGLRVDGSSLVAVVEIAPPRDYLTRIGrhs-fdASHLLPTAALANCLYQ-HDI 146 Rhodococcus ery...
WP_005114610  73 SSGsiadT------------PSGqDSWTGTRWENGKLITVLEISATQRHPSVITpdh-caTDSLVPLRVLRECMHQ-NDI 138 Mycobacterium a...
WP_011207376  87 VDF----R------------GPD-DRSLGLYWDGSRVVTVVEVLPPRGGLTRISsst-vlASHLLPLPELAKCLNQ-HDI 147 Nocardia farcinica
WP_011726653  81 SEPavgsT------------VMP-GDHVAVRWQGDYLIAVIELVPRPFTPTVIVngs-amTDDVVNTKLVERLLEA-HCP 145 Mycobacterium s...
WP_015294706  79 SEPvvgaT------------VKP-GDHVAVRWQGEFLVAVIELIPRPFTPTVIVdgq-ahTDDMLDTGLVEELLSV-HCP 143 Mycobacterium c...
WP_011207355 111 AGGeavdV------------PLAeGGSYGVRWDNGLLITMMRIDPPPDALTLLRrgs-lsTDQVLPLTEIGRCLSQ-FDI 176 Nocardia farcinica
WP_011896186  95 QWPaaldV------------PTG-GVPIGVVSENETLTMMVELRPDPIAPSVVTdte-erTINTISIAMLTEMMNV-LDV 159 Mycobacterium g...
WP_011767971  81 Aaa--vdV------------PHG-NIVCGVRVEAYEALTMIEVTGKPYSLTFLRgstvslTRNVLPLEVLTELLDQpGGI 145 Mycobacterium s...
WP_031712046  75 NDPit--------------lANN-RSGGGVRVQDGVAVVAVQLLGRAHRATTVTgsvtveSDNVIDVVELAPLLRHpLDL 139 Mycobacterium t...
WP_010983978 203 RLESAQIVLHTQPAP--AlhlpqQSVAVTNYAPLQAQTGAPAVRITWIALKLDPELCPEAVS-ARgG-GLVGAQKCVVRA 278 Streptomyces av...
WP_003940702 147 SLTGIDIVSHGYRAA--S-----GTPATEVYERLIGPLPATATRSVWLALRFDALEGGAAVE-RRgG-GEQGAGRAIAVA 217 Rhodococcus ery...
WP_005114610 139 ELESIDVISNGQRTA--Q-----GTVLRGGYDRLVGPLPAVAIRTVWVVLRFDPGANVDAVFrRG-G-GRRGAERCAVIA 209 Mycobacterium a...
WP_011207376 148 LLSGIDIISHGHRSR--A-----GTPAGKIYETLLGPLPATAHRSVWLAISFDAVACPGAAE-RRgG-GTEGASRAVTIA 218 Nocardia farcinica
WP_011726653 146 DLEA-DVVSAGYRVGktA-----PASLIALYEQVVGPYPAPANRRTWIVLRADPEKTQRSAH-RRdS-GVSGLARYLVAS 217 Mycobacterium s...
WP_015294706 144 DLEA-DIVSAGYRVGntA-----APDVVSLYQQVIGTDPAPANRRTWIVLRADPERTRKSAQ-RRdE-GVAGLARYLVAS 215 Mycobacterium c...
WP_011207355 177 QLASIDVISTGARTA--S-----NGIVARLYDSIIGPLPAIAHRTVWLVLRLDPLANVRAVD-NRgG-GATGTLRTAIIA 247 Nocardia farcinica
WP_011896186 160 ELDSIDLLGDGFRAV--G-----G--FSDLYQQMTGPTPAAAARSNWIVLRMRLYENLAAID-RR-GrDIESAHRVAATT 228 Mycobacterium g...
WP_011767971 146 QLAAIDVVPAGHRVR--R-----GNEYPPLYSTLLADRPAAGQRTMQFVVRLDIRNSVPGLQ-YR-----QSVGAAAAAA 212 Mycobacterium s...
WP_031712046 140 ELDSISVVTFGSRTG--T-----VGDYPRVYDAEIGTPPYAGRRETWLIMRLPVIGNTQALR-WR-----TSVGAAAISV 206 Mycobacterium t...
WP_010983978 279 ADHLTSRLTGAGFRTTVLNEEELTAAIATSACANPLVTAGagrtearerrteE--------------------------- 331 Streptomyces av...
WP_003940702 218 ANRVIRVLDSAGCKARILTAPEIASSTAQVTRGVAGHEVT------------E--------------------------- 258 Rhodococcus ery...
WP_005114610 210 TARVRRALAAAHCASTILQAGQIHRISAEMLRQYAGAPMH------------E--------------------------- 250 Mycobacterium a...
WP_011207376 219 TQRIMRALEDADCNARILTAPEIRKAVLQITAGYDPRALT------------H--------------------------- 259 Nocardia farcinica
WP_011726653 218 ATRIADQLASNGVDARCCRSFDDYEKATEISYE------R------------E--------------------------- 252 Mycobacterium s...
WP_015294706 216 ATRIADRLASHGVDAVCGRSFDDYDHATDIGF------VR------------E--------------------------- 250 Mycobacterium c...
WP_011207355 248 TRRVANRLAALDISTSVLTASEMNAAVRVLTRGVALEDFA------------E--------------------------- 288 Nocardia farcinica
WP_011896186 229 CLRAADMLAAKGIDAVPASAAQIDAVNAALHDDTPTVD------------------------------------------ 266 Mycobacterium g...
WP_011767971 213 TERIINALLERDIRATALTAAELDTALDRLGARLQPAPVP------------Pviegtdspadpvpfrstspaqrrskvs 280 Mycobacterium s...
WP_031712046 207 AQRVASSLRCQGLRAKLATATDLAELDRRLGSDAVAGSAQ---------------------------------------- 246 Mycobacterium t...
WP_010983978 332 ---SGRSWRCDNRRHTTYWVRRWPLvggdgrsLPQLVALLTAVPALATTFS--------LTLAhgeRGE-VSL------- 392 Streptomyces av...
WP_003940702 259 ---TWRSTPLPGVSNVGFGIEPRFI-------TTATLTRVWAVATVGTSVT--------IRLR---PTG-QRG------- 309 Rhodococcus ery...
WP_005114610 251 ---DWSGLTLIDSYNVAMGIDPWYI-------TDATLTGLWARPTLETSVT--------VRLR---PAAkGRT------- 302 Mycobacterium a...
WP_011207376 260 ---RWRYAELGNAVNIGSAVDPDHL-------GSDLLAQLWVAPSRGTTVT--------VRLR---PGS-SAE------- 310 Nocardia farcinica
WP_011726653 253 ---TWSSIKGRSTFTAAYTAPGGPD-------M------WWSARADHTITR--------VRVR---PGA-APS------- 297 Mycobacterium s...
WP_015294706 251 ---KWSMIKGRDAYTAAYAAPGGPD-------V------WWSARADHTITR--------VRVA---PGM-APQ------- 295 Mycobacterium c...
WP_011207355 289 ---TPHSLVHDGVHLTSYEIGPELI-------GSRGFADIWATPSMSTTVT--------VRLR---PGE-QRSaqpedsp 346 Nocardia farcinica
WP_011896186 267 ---HWSHMESRQGYASVYYADPAHI-------SVDS-PQWWTWTLAQRTST--------LIRL---SRA-GGD------- 316 Mycobacterium g...
WP_011767971 281 nevGWRTIKGHPGFLTTYYFSPEDI-------TTASLHQMWALRSDEVVLTlslfkrryVEAP---DGD-GPV------- 342 Mycobacterium s...
WP_031712046 247 ---RWKAIRGEAGWMTTYAYPAEAI-------SSRVLSQAWTLRADEVIQN--------VTVY---PDA-TC-------- 296 Mycobacterium t...
WP_010983978 393 --C--GHLRVTGRSDDELVaarraleeaaRRGGAGLARLDRQQLPGVLATLPLGGA 444 Streptomyces avermitilis
WP_003940702 310 --EakVSATCRFTTRNPPE----------NAPLAGLVSLRGRQRDGLLTNLPTALA 353 Rhodococcus erythropolis
WP_005114610 303 --S--VGALVRWATDEQLP----------VRHSTGMTSLNGSQRDAFFAGLPVGAI 344 Mycobacterium abscessus
WP_011207376 311 --TvnIGASWRLTARELPE----------RAKQTGMISMNGRHREGLLANLPLAVP 354 Nocardia farcinica
WP_011726653 298 --S-----AILLTTLANPT----------TP--RGFSCLFGGQRAALQGIVPVSDK 334 Mycobacterium smegmatis
WP_015294706 296 --S-----TVLLTTADKPK----------TP--RGFARLFGGQRPALQGQHLVANR 332 Mycobacterium canettii
WP_011207355 347 piT--LGALVRFDTEAEPT----------APPVAGLRPLPGRQFRALLDCLPAQFT 390 Nocardia farcinica
WP_011896186 317 --TvnIAALVRYRTAARPT----------APPVSRLGPLYGVQ-PAMWRQFRIGYl 359 Mycobacterium gilvum
WP_011767971 343 --M--IAATVRTNDPQPPQ----------QPPTLYLNTLPGDQFSAALRPAPTARP 384 Mycobacterium sp. KMS
WP_031712046 297 ------TATITVRTPTPAP----------TPPSVILRRLNGEQAAAAAANMCGPRP 336 Mycobacterium tuberculosis
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