Conserved Protein Domain Family
SrtB_LPKTxSAVK

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NF040525: SrtB_LPKTxSAVK 
class B sortase, LPKTxAVK-specific
This branch of the class B sortase family is found in multiple species of Streptococcus and Gemella. It processes target proteins that end with the motif LPKTxAVK-COOH, which differ from most sortase recognition sites in lacking an additional C-terminal transmembrane helix. Substrates of this sortase include the amylase-binding adhesin AbpA, as well of other proteins with similar N-terminal and C-terminal domains but unrelated central regions.
Statistics
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PSSM-Id: 439740
Aligned: 26 rows
Threshold Bit Score: 436.72
Created: 11-Oct-2024
Updated: 3-Dec-2024
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_075565294  17 GFLIVVAVVISGFFVYnnfLAPLDKTSSTTSTTVVQgtttVEAPKPTYTVSAEEKEYLANRFKPLTETNSETVAYVYAPG 96  Streptococcus t...
WP_018369263  18 VLAIIFLLVFLPQINSq--KENDSKESTTKTTISKEkkveSSKPKETYHLSEAEKEQLRQRFTSLKEINQEVIAYIYAPG 95  Streptococcus m...
WP_116877450  12 LLLVFFAAVGAISFFR----TDSGQSSVLPSKQSSV-----PSSQSRYTVSQEEKNYLKARFADLWAVNPETVAYIYAPG 82  Streptococcus c...
WP_075099393  18 LFVALLAVFFTLTFFN------RQEESRQVSPSISSsirqTSSTAAPYQVSIEEKEYLTQRFAPFLEVNAETIAYVYAPG 91  Streptococcus a...
WP_076995586  19 LLLVMFAIFLTVKNFS----GRTAKPDIIPSSSTSLd---AKSLSDATRLAAVEREALKQRFTPLLEVNPETVAYIYAPG 91  Streptococcus
WP_209551243  19 LWGLIFVILAAVLLSQ----HFKHVSSQQAAKPSVR-----LYPEQTSASSQSEKDYLANRFKPLKAVNADTIAYVYAPG 89  Streptococcus p...
WP_004184505  19 GICLLLIVLVIFSVFY------SFRSSASGSKLRVShpsrIEMSSSSASSSQTEKEYLAERFAKLKAVNSETIGYVYAPG 92  Streptococcus s...
WP_004392774  13 ILLLAIALVISAVFVA----GCSDDKGTSSNTSSKA----------TYTVSKEEKDYLSKRFSELSKTNNETVAYVYAPG 78  Gemella haemoly...
WP_168548221  21 ILGLGGLIWTGTQVFQt--KPTETKPNTTQTTVSSTppssTEPPKKVYTVSEEEKAYLKSRFDPLLALNKDTIAYVYAPG 98  Streptococcus o...
WP_018372818  21 LMAIAGAGLLTTHYLQt--KQATAPSTSLTTTSSSStipsSSEKPKDYIVSEEEKAYLKSRFEPLMALNASTIAYVYAPG 98  Streptococcus m...
WP_075565294  97 TQLDEPVVQTTDNATYLDKTFDGGHQPYLGTVFMDADNKKDFSDRLTWLFGHARGSKVADHRMFNDVNFYDTQKYFDEHP 176 Streptococcus t...
WP_018369263  96 TQLDEPVLHTRDNYKYLEQTITGEYSPYMGAVFMDKDNYPNFQDRLTWLFGHARGSTVSDHRMFNDVNFYDNQTYFNEHP 175 Streptococcus m...
WP_116877450  83 TMLDEPVVQTGDNETYLNKTFDGGYEPYMGTVFMDEDNSKDFDDSLTWLFGHARGSTVADHRMFNDVNFYDSQSYFDEHP 162 Streptococcus c...
WP_075099393  92 TKLDEPVVQTTDNATYLDKTFDGNHEPYMGTVFMDTDNRKDFQDQLTWLFGHARGSQVPDNRMFNDVNFYDDQHYFDTHP 171 Streptococcus a...
WP_076995586  92 TMLDEPVVQTGDNATYLDKTFDGGYEPYMGTVFMDTDNRKDFTDRLTWLFGHARGSAVPDHRMFNDVNFYDKQDYFDQHK 171 Streptococcus
WP_209551243  90 TKLDEPVVQTNDNASYLVKTFEGGRDAYMGTVFMDKDNQKDFSDRLTWLFGHARGSKAGDHRMFNDVNYYDRQDYFDQHK 169 Streptococcus p...
WP_004184505  93 TQLDEPVVQTKDNATYLLKTFEGKQEPYMGAVFMDKDNHKDFSDRLTWLFGHARGSKAGDHRMFNDVNYYDRQDYFDKHR 172 Streptococcus s...
WP_004392774  79 TQLDEPVVQTNDNETYLDKTFEGGHVPYLGTVFMDMDNKKDFHDRLTWLFGHARGSKVGDHRMFNDVNYYDKQEYMDKHK 158 Gemella haemoly...
WP_168548221  99 TMLDEPVVQGTDNGHYLQYTIDGQYSPYLGTVFMDYENSKAFDDSLTWLFGHARGSTVPDHRMFNDVNFYEDQAYFDQHR 178 Streptococcus o...
WP_018372818  99 TMLDEPVVQGTDNSHFLQYTIDGQYSPYLGTVFMDYENSKNFDDSLTWLFGHARGNTVPDHRMFNDVNFYEDQTYFDQHR 178 Streptococcus m...
WP_075565294 177 YVVIETPERKYYYEAVAMVIVPEDTAFYRTSFDDDQDFEKQLTAIYNEANVKKPNMKVSAKDKYLVLSTCREEDETIRAN 256 Streptococcus t...
WP_018369263 176 YFVIETPERYYYYEAAFMIIVPETTSFYRTSFENDHVFLEQLREVQKEAIVKNEAIEINASDRYLVLSTCREEDKSIRSN 255 Streptococcus m...
WP_116877450 163 YLVAETPSRKYYYEAAFMIIVPETTALYQTSFDSLADFKNQLAQVAQEAHTKNAELLIDENDKYLVLSTCREEDETIRSN 242 Streptococcus c...
WP_075099393 172 YVVIETPERKYYYEAAFLIIVPENTAFYRTKFASNDEFKAQLEAVSKDAATRNSTIKINADDRYLVLSTCREEDETIRSN 251 Streptococcus a...
WP_076995586 172 YLVVETPERKLYYEAVGLVIVPEETAFYRTTFADDEDFLTQLRNIYAIAQTKNPNIEIKASDRYLVLSTCREEDETIRSN 251 Streptococcus
WP_209551243 170 YVVIETPERRLYYEAMGLVIVPEETAFYRTEFKNDEDFTGQLRKIYEESRTKNSAIDIRAEDKYLVLSTCREEDDTIRSN 249 Streptococcus p...
WP_004184505 173 YVVIETPERKYYYQAMGLVIVPEETAFYRTEFKDDEDFTTQLRNIYEAARTKDPKIKIKASDRYLVLSTCREEDDTIRSN 252 Streptococcus s...
WP_004392774 159 FVVIETPERKYYYEAAFLTIVPETTSFYRLDFENDEDFLNQLTNVKKDAATKNDSVQLKGNDKYLVLSTCREEDETIRSN 238 Gemella haemoly...
WP_168548221 179 YVVIETPERKYYYEAAFFIVVPETTGFYRTSFESKESFAQQLTDVSKEARTKANNITINPDDKYLVLSTCREEDETIRTN 258 Streptococcus o...
WP_018372818 179 YVVIETPERKYYYEAAFFIIVPETTGFYRTSFESKEVFAEQLSTVSKDARTKAQNIIINPDDKYIVLSTCREEDETIRSN 258 Streptococcus m...
WP_075565294 257 LYLRQIPDSEMEEFVKQHGEQLAYKATR 284 Streptococcus timonensis
WP_018369263 256 LYLRQIPDTELPEFLVKNKERLTYMPTR 283 Streptococcus marimammalium
WP_116877450 243 LYWRQIPDDELSDFLAKEGDRLVYQKTR 270 Streptococcus chenjunshii
WP_075099393 252 LYLRQIPDKELIEFLANHGNDLGYVATR 279 Streptococcus acidominimus
WP_076995586 252 LYMRQISEQELGSFLATHGADLEYVATR 279 Streptococcus
WP_209551243 250 LYLRQIPDTELEEFLAQHGDQLAYAPTR 277 Streptococcus panodentis
WP_004184505 253 LYLRQIPDSELPDFLAKHGKELTYTPTR 280 Streptococcus sanguinis
WP_004392774 239 LYLRQIPDNEMNDFLAKHKDELKYVATR 266 Gemella haemolysans
WP_168548221 259 LYLRQIPDEELVDFLEEHSSELVYQPTR 286 Streptococcus ovuberis
WP_018372818 259 LYLRQIPDSDLTAFLAEHGESLTYKPTR 286 Streptococcus merionis
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