Q27886 55 SDLLHSRalrSIQLACRTHPATVISAFEGVQEGLQNCANRLRFQQWDCSEA-G---N-IMH---DPPLLRQGFRESSLIW 126 Caenorhabditis ... XP_220546 116 SIPGLVP---KQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTV-S---NsLAI---FGPVLDKATRESAFVH 185 Norway rat NP_001079343 44 TIPGLVA---KQMRFCRNYMEIMPSVAEGVKIGIQECQHQFRGRRWNCTTVnD---N-LAI---FGPVLDKATRESAFVH 113 African clawed ... P21551 59 SLQLLSR---KQRKLIRQNPGILHSINSGLQSAMKECKWQFRSRRWNCPTT-G---G-DNI---FGKIVNKGCRETAFIF 127 axolotl XP_003252539 101 SLQLLSR---KQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTA-P---G-PHL---FGKIVNRGCRETAFIF 169 White-cheeked G... P21552 43 NVPGLVS---RQRQLCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNCNTL-Dr--D-HSL---FGRVLLRSSRESAFVY 112 house mouse NP_001037315 57 vHATLRR---KQRRLARENPGVLAAVAK-AQYAFAECQHQFKYRRWNCSTR-NflrG-KNL---FGKIVDRGCRETAFIY 127 domestic silkworm NP_001081637 22 SAWSVNN---FLMTGPKAYLTYSASVAVGAQNGIEECKYQFAWERWNCPES-T---L-QLA---THNGLRSATRETSFVH 90 African clawed ... NP_493668 44 SLKGLTR---RQMRFCKKNIDLMESVRSGSLAAHAECQFQFHKRRWNCTLI-D---P-VTHeviPDVFLYENTRESAFVH 115 nematode NP_571034 22 CGWSVNN---FLMTGPKAYLIYSSSVAAGAQSGIEECKYQFAWDRWKCPER-A---L-QLS---THSGLRSANRETAFFH 90 zebrafish
Q27886 127 ALSSASAAWGVATACAQGWIDDCACNNQMG---------Q------NEYEFGGCTHGVQHGITASRKLLTKVGA-V---- 186 Caenorhabditis ... XP_220546 186 AIASAGVAFAVTRSCAEGSAAICGCSSRLQ---------Gsp---gEGWKWGGCSEDIEFGGMVSREFADAREN-R---- 248 Norway rat NP_001079343 114 AIASAGVAFAVTRSCAEGSATICGCDTHHK---------Gpp---gEGWKWGGCSEDMDFGSMVSREFADAREN-R---- 176 African clawed ... P21551 128 AITSAGVTHSVARSCSEGSIESCTCDYRRR---------Gpg---gTDWHWGGCSDNIDFGRVFGREFVDSSER-G---- 190 axolotl XP_003252539 170 AITSAGVTHSVARSCSEGSIESCTCDYRRR---------Gpg---gPDWHWGGCSDNIDFGRLFGREFVDSGEK-G---- 232 White-cheeked G... P21552 113 AISSAGVVFAITRACSQGELKSCSCDPKKK---------GsakdskGTFDWGGCSDNIDYGIKFARAFVDAKERkG---- 179 house mouse NP_001037315 128 AITSAGVTHSLARACREASIESCTCDYSHRpraaqnpvgGra--nvRVWKWGGCSDNIGFGFRFSREFVDTGER-G---- 200 domestic silkworm NP_001081637 91 AISSAGVMYTLTRNCSMGDFDNCGCDDSRN---------Gri--ggRGWVWGGCSDNAEFGERISKLFVDGLET-G---- 154 African clawed ... NP_493668 116 AISSAAVAYKVTRDCARGISERCGCDYSKN---------Dhs--gkSQFQYQGCSDNVKFGIGVSKEFVDSAQR-Rvlmm 183 nematode NP_571034 91 AISSAGVMYTLTRNCSLGDFDNCGCDDTRN---------Gqr--ggQGWLWGGCSDNVGFGEVISKQFVDALET-G---- 154 zebrafish
Q27886 187 ---------------NTLLRKVEKHNLKAGRLAIKKTLISSCKCHGVSGSCQQKTCWKRTATLEHITDYLVEKYARAKLY 251 Caenorhabditis ... XP_220546 249 ---------------PDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEM 313 Norway rat NP_001079343 177 ---------------PDARSAMNRHNNEAGRTSILDHRHLKCKCHGLSGSCEVKTCWWSQPDFRVIGDYLKDKYDSASEM 241 African clawed ... P21551 191 ---------------RDLRYLMNRHNNEAGRMTVFSEMKQECKCHGMSGSCAVRTCWMRLPTFRAVGDFLKDRFDGASRV 255 axolotl XP_003252539 233 ---------------RDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRV 297 White-cheeked G... P21552 180 ---------------KDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGEYLWRKYNGAIQV 244 house mouse NP_001037315 201 ---------------KTLREKMNLHNNEAGRRHVQTEMKQECKCHGMSGSCTVKTCWMRLPSFRSVGDSLKDRFDGASRV 265 domestic silkworm NP_001081637 155 ---------------QDARALMNLHNNEAGRLAVKETMKRTCKCHGISGSCSIQTCWLQLAEFRDIGNHLKIKHDQALKL 219 African clawed ... NP_493668 184 kddngtsllgpsqlsADGMHMINLHNNQAGRQVLEKSLRRECKCHGMSGSCEMRTCWDSLPNFRHIGMAIKDKFDGAAEV 263 nematode NP_571034 155 ---------------QDARAAMNLHNNEVGRKAVKGTMQRTCKCHGVSGSCTTQTCWLQLPEFREVGNYLKEKYHRAVKV 219 zebrafish
Q27886 252 TDDSV-----------------------------------VKTTDLIYLEASPDVCKAKSVA------GRVCAWRNETHT 290 Caenorhabditis ... XP_220546 314 VVEKHresrgwvetl----------------rprytyfkvPTERDLVYYEASPNFCEPNPETgsfgtrDRTCNVSSHGID 377 Norway rat NP_001079343 242 VVEKHresrgwvetl----------------rpkytffkpPIERDLIYYESSPNFCEPNPETgsfgtrDRECNVTSHGID 305 African clawed ... P21551 256 IYGNKgsnrasrvqth-------------hlepenpthkpPSPQDLVYFEKSPNFCTYNGKTgtsgtsGRVCNSSSLGLD 322 axolotl XP_003252539 298 LYGNRgsnrasraell-------------rlepedpahkpPSPHDLVYFEKSPNFCTYSGRLgtagtaGRACNSSSPALD 364 White-cheeked G... P21552 245 VMNQDgtgftva----------------------nkrfkkPTKNDLVYFENSPDYCIRDREAgslgtaGRVCNLTSRGMD 302 house mouse NP_001037315 266 MLSKAdvetpaqrneaaphrvprkdryrfqlrphnpdhksPGVKDLVYLESSPGFCEKNPRLgipgthGRACNDTSIGVD 345 domestic silkworm NP_001081637 220 EMDKRkmrsgnsadn---------------rgaiadafssVAGSELIFLEDSPDYCLKNISLglqgteGRECLQSGKNLS 284 African clawed ... NP_493668 264 KVVKEdgiekpriv------------------mknsqfkrHTNADLVYMTPSPDFCESDPLRgilgtkGRQCTLAPNAID 325 nematode NP_571034 220 DLLRGagnsaasrg------------------aiaetfnsISRKELVHLEDSPDYCLENRTLglpgteGRECLRKGKNLS 281 zebrafish
Q27886 291 q---gDCDRLCCGNGFSI--R--HEVVRVKCDCEFVWCCNLVCKDCIQHRWISTCN 339 Caenorhabditis elegans XP_220546 378 -----GCDLLCCGRGHNA--R--TERRREKCHCVFHWCCYVSCQECTRVYDVHTCK 424 Norway rat NP_001079343 306 -----GCDLLCCGRGQNT--R--TEKRKEKCHCIFHWCCYVSCQECMRVYDVHTCK 352 African clawed frog P21551 323 -----GCELLCCGRGYRT--K--TQRVTERCHCTFHWCCHVSCLNCTNTQVLHECL 369 axolotl XP_003252539 365 -----GCELLCCGRGHRT--R--TQRVTERCNCTFHWCCHVSCRNCTHTRVLHECL 411 White-cheeked Gibbon P21552 303 -----SCEVMCCGRGYDT--S--HVTRMTKCECKFHWCCAVRCQDCLEALDVHTCK 349 house mouse NP_001037315 346 -----GCDLMCCGRGYKT--N--TMFVVERCNCTFHWCCEVKCKLCRTEKVVHTCL 392 domestic silkworm NP_001081637 285 qwerrSCKRLCTDCGLRV--EekKTEIISSCNCKFHWCCTVKCEQCKQVVIKHFCa 338 African clawed frog NP_493668 326 -----DCSLLCCGRGYEK--K--VQIVEEKCNCKFIYCCEVRCEPCQKRIEKYLCL 372 nematode NP_571034 282 kwekrTCKRLCGDCGLAVeeR--RAETVSSCNCKFHWCCAVKCEQCRKTVTKYYCv 335 zebrafish
Jiyao W et al.(2023). "The conserved domain database in 2023.",