Conserved Protein Domain Family
KCT2

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pfam17818: KCT2 
Keratinocyte-associated gene product
This entry includes Keratinocyte-associated transmembrane protein 2 found in humans. Functional studies show that KCP2 localizes to the endoplasmic reticulum, consistent with a role in protein biosynthesis, and has a functional KKxx retrieval signal at its cytosolic C-terminus.
Statistics
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PSSM-Id: 407686
Aligned: 5 rows
Threshold Bit Score: 234.826
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_005001320  76 PSKAHVT--TTLPPPTATEKSRAPTAAPRPPPTSSPLPEEAEDHEDPSLEEDEgLL-----TPNSPPSPVKDPLDN-GD- 146
XP_003123986  79 PSLSQVS--TTLAPATRTEKSRVASVSPYSSPATSLSQEEADNNEDPSIEEED-LL-----TLNSSPPTARDTLDN-GD- 148
KFO26599      59 PSVSRVT--TTLPAPTGPEKSRGTLAAPHPSLTTSVLPEAADNNADQSLEEED-LL-----VPNGSPSPARDALDN-GD- 128
KFW79987      40 PTTAKISsvTAGKAPTA-KGDS----SSSVLPASLVPP--VDASEDTKIEDED-LLtdlkdTLNSSPPIIKETLESdGDd 111
NP_694757     72 PSVSQIS--TTLSPASA-EKSGSSSAAPTPTAAPSAPEEEADSNEDPSMEEED-LL-----ALNSSPATGKDTLDN-GD- 140
XP_005001320 147 YGEADYDWTTSPR--------D-EESDE----ALEENRGYVEIEQSVKSFKSPSSDVEEEDSHFFFHLIIFAFCIAVVYV 213
XP_003123986 149 YGEPDYDWTASPR--------D-EESNE----ALEENRSYMEIEQSVRSFKTPPSNVEEEDSHFFFHLIIFAFCIAVIYV 215
KFO26599     129 YGEPDYDWTTSPR--------D-EESEE----TLEENRGYLEIEQSVKSFQSPASNIEEEDSHFFFHLIIFAFCVAIVYV 195
KFW79987     112 YGP--YEMTPISRyspdlempDdDDSDT----ISNYNEEIKTLDEKIKGVSVSGLE-EEEDSHFFFHLVVVAFLVAVVYV 184
NP_694757    141 YGEPDYDWTTNPR--------D-EEPEDiniaISKESRRFRGFQDSVEVVKLPPPN--REDSHFFFHLLIFAFCAAVVYV 209
XP_005001320 214 TYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVHEAMPSLKITNDYIF 263
XP_003123986 216 TYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVNEAMPSLKITNDYIF 265
KFO26599     196 MYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVHEAMPSLKITNDYIF 245
KFW79987     185 TYHNKRKLFLLVQSRRWRDGLCSRTVEYHRLDQNVNEAMPSLKITNDYVF 234
NP_694757    210 TYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVNEAMPSLKITNDYIF 259
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