Conserved Protein Domain Family
PRK05031

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PRK05031: PRK05031 
tRNA (uracil-5-)-methyltransferase; Validated
Statistics
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PSSM-Id: 235332
Aligned: 217 rows
Threshold Bit Score: 469.695
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
32266192    8 ICGGCTNIQDYSTQLQAKHNLTLQEFQSFLDTKSknfqyptnplaiEVFASPQEGFRARAEFRFS-HVfqnksGlD---- 82 
121613439   1 ---MSLENFGNFLTLDEKHSFIKKYFKEFYTKDF------------KLFTSKDKHYRTRAELSFY-HE-----N-Dtl-- 56 
57237672    1 ---MSLENFGNFLTLDEKHSFIKKYFKEFYTKDF------------KLFASKDKHYRTRAELSFY-HE-----N-Dtl-- 56 
222823969   1 ------------MHFEEKIALNKALFSSLYDKEI------------QCFKSPLKAYRTRAEFCIYhHE-----N-Gei-- 48 
34558377    8 TCGGCALALPYEEQWKLKESEFRELLPLSKDTPT------------DLYPSAPHSFRARAEFRLY-RN-------Esgrl 67 
157738407   9 CASCTLFDKTYEEQLNYKIQREKERFSNFTNIDF------------DIIKSNESNFRNRAEFRIW-WEkgennK-Eil-- 72 
296274443   9 CGSCTLYHMNYEEQLAYKLSREKQRFQDITTMDF------------EIIRSEEEHFRNRAEFRFW-KNyddekN-Ptl-- 72 
152993415   9 CGSCALYNQNYTQQLQLKEQRVSELLSPFYTGEL------------ELFDSPDSRYRARAEFRIW-HE-----S-Erc-- 67 
152990451   9 CGSCSLYEGGYEEQLQKKVHEFEKLFG----LEP------------EIFPSKQSRYRARAEFRYIdg------------- 59 
224373183   9 CGSCVLWEMPYDEQLKMKSEKLKEMFSEFDMPEI------------EVVHGSDEHFRARAEFRVW-HE-----G-Dks-- 67 
32266192   83 -FAMNAFGYNHR----VPIKKCPILLPTLQDIMPLLLHYLN-TYDLLNHKLYACNLLSSLQNEIIITLIYHKSLDSHWES 156
121613439  57 fYAMFDPKSKKK----YIIEYLDFADEKICAFMPKLLEYLR-QDDKLKEKLFGVEFLTT-KQELSVTLLYHKNI-EDIKS 129
57237672   57 fYAMFDPKNKKK----YIIKYLDFADEKICTFMPKLLEYLR-QDNKLKEKLFGVEFLTT-KQELSVTLLYHKNI-EDIKS 129
222823969  49 sYAMYE--NKKK----IPIKNFEIADEKIQAYMPILLDNL---NENLKHKLFGVEFLAT-KIDLSITLLYHKNIES-ITQ 117
34558377   68 sYAMSQKGSKQP----LPIQSCPILLPSIQALMPSLLEALE-SDEILTQKLFGVEFLSGLSQEVLVSLLYHKRLDHAWEE 142
157738407  73 sYAMND-FKKNI----LKINSCEMVSFHIKELMPKLIDELQ-NDLELSFKLFAVEFLGSSTKDMLVTLIYHKKLEESWIQ 146
296274443  73 sYGMTS-FDKNI----LEVDKCSIVSKQIDELMPKLLDEIS-QSEILNYKIYSVEFLGSTTNDMLVTLIYHKKLDTTWEK 146
152993415  68 dYAMGNIEKKGA----VTIEECPKVIEPIEKRMWKLLEKINaSQEVLKQRLFAVEFLATTTDECLVTMLYHRKLDEAWSE 143
152990451  60 eYAMHRLHEKGL----VTIDACEMVLESIYELMSKLRLLIN-KHEILSNRLYRVDFLSGLSGESLVTMVYHRPIDEAWEK 134
224373183  68 yYAM--RKRKEDgrgvIPIEECKIVDKAIYDIMTPLLKEIE-KNDNLRFKLYEIDFLSNSKGELIITLIYHKKVDESIAE 144
32266192  157 LALKIQKELeytlntNIHIIGRSKNHKHILSNDIICEHLTLfantpKERTYTFFKQESRFCQPNPFINTQMLEFIVSALS 236
121613439 130 NLENLSNNL------HINLIARSKGKKLIFKTENLRQTLNI-----QDRKIFYEFNNDCFIQPNTAINEKMITWVCEILN 198
57237672  130 NLENLSNIL------HINLIARSKGKKLIFKTENLRQTLNI-----QGRKIFYEFNNDCFIQPNTTINEKMITWVCEILN 198
222823969 118 DLQELSKKL------NLKLIARSRGKKLVFNGENLKQILNI-----KNKEIFYEFNNDCFIQPNTTINEKMIEWVIDLLE 186
34558377  143 RALGLLSSLpt----lsSLIGRSKGQKIVLGESFITETLTI-----DSKPWRFLHYEGSFTQPNPKVNEKMIEWIISAPP 213
157738407 147 KAKEIEKKL------NIKIIGRSKKQRLVLTNDYINETLNI-----SNQNFFFAYEENGFTQPNTNVNVQMIEWVLENTK 215
296274443 147 VAKEVQERL------NIKIIGRSRKQKIVLKEDFIKEELNI-----NDNVFKFHYKEGGFTQPNTKVNIKMIEWVLNNIE 215
152993415 144 EAKMLEREL------NCRVMGRSRKQKVILSDEFVTETLEI-----DGKEFTYVQYESGFTQPNPAVNVKMIEWAIWQAK 212
152990451 135 AANEIAKAL------HIDIVGRSRGKKIVIGKEYITEKLPV-----FEKEFLFRHYEGSFTQPNPYVNIKMIEWAGRIAK 203
224373183 145 DIKKLKEKFk-----NADFIVRKKGRKYVFDKNYLIEELNI-----NSKTYKYKIIENTFSQPNRQMNQKMIEWAMRNSE 214
32266192  237 SiytPQtpCDMLELYCGSGNFTIPLASIFRHIFATEVVKSAITLLQKNMAKNNIENIIPARLNAFESIQALRKERVFFRL 316
121613439 199 T---QKr-MDLLELYCGYGNFTLALAPFFFKVLATEISKSNINFALKNCELNNTTNIHFARLSSEELSLAIKKEREFFRL 274
57237672  199 T---QKr-MDLLELYCGYGNFTLALAPFFFKVLATEISKSNINFALKNCELNNTTNIHFARLSSEELSLAIKKEREFFRL 274
222823969 187 K---EEr-KDLLELYCGYGNFTIALAKYFNKILATEISKKNIEFALKNCDLNSIKNISFTRLSSEELSQALKKEREFNRL 262
34558377  214 Q-------GDLLELYCGAGNFTLPLSSRYAKILATEVSKTSIHAAKQNCELNSVRHISFVRLNAQETQSALEGEREFYRL 286
157738407 216 N---SS--KDLCELYCGGGNFTIPLSTKFRKVLATEISKTSIKSALRNCSLNKIESISFIRMSAEDFVQALNKVRAFNRL 290
296274443 216 T---KD---DLCELYCGGGNFTIPLSTKFNKVLATEISKTSINSALLNCELNNITNIDFIRMSAEEFVEALNSVREFRRL 289
152993415 213 K---VGy-GDFLESYCGLGNFTLPLSHYFDNVLATEISKRSIHAALQNCELNAVENITFARLASEEMTEALNGVREFSRL 288
152990451 204 D---LQ--GDLLELYCGAGNFTLPLSRYFEKVLATEVNKSSIKAAKENVALNGIENVEFVRLSSQEVTQALRGVRDFRRL 278
224373183 215 D---LK--GDLVELYCGNGNFTIPLSERFNKVIATEISKESIEAATYNAEINARDNITFLAMSAAEFSKLYKDRSPL--- 286
32266192  317 KNIDLDAFAFDCVLIDPPRSGVgEEEVLYFLQNFNTIIYVSCNPHTLLNDLRILSQSHYVMRFGLFDQFPHTYHRECIVI 396
121613439 275 KDIRLDDFNFSHVLVDPPRAGL-DKSVIDLIKKYENIIYISCNPITLKENLKELSLTHRVEEFALFDQFVNTPHLECGVF 353
57237672  275 KDIRLDDFNFSHVLVDPPRAGL-DKSVIDLIKKYENIIYISCNPITLKENLKELSLTHRVEEFALFDQFVNTPHLECGVF 353
222823969 263 KGIDLDGFNISHVLVDPPRAGL-DVSVIELIKKYENIIYISCNPITLRENLEILSQSHEILNLAFFDQFANTSHLECGVH 341
34558377  287 RELDLPSYDFQAVFVDPPRAGL-GAEVASFLRRFDQILYISCNPKTLQSDLEVLQLSHDVERFALFDQFPYTPHLESGVI 365
157738407 291 KDINLDDYEFDTIFMDPPRSGL-DDTTRNLAKDFENIIYISCNPETLHRDLEELTKTHEIEKFALFDQFAFTNHIESGVI 369
296274443 290 KDINLSDYNFSTIFVDPPRSGL-DDTTRELVKNYEQIIYISCNPETLHRDLKELIKSHQILNFSLFDQFSYSGHIETGVI 368
152993415 289 KGIDLKSYDFSTVLVDPPRAGL-DEGTIELISNIDNIIYISCNPETLARDLETLIKTHTVMEAALFDQFPHTEHVESGVF 367
152990451 279 ENIDLHSYNFQTVFVDPPRCGL-DDDTRELVREFDNIVYISCNPQTLHRDLEELSKTHTVQKVAVFDQFPYTPHLESGVY 357
224373183 287 ----ITKYDLKNILIDPPRAGL-DDKSREFVNEFDNIIYISCNPETLQRDLKTLAKGREIKAFAFFDQFPYTNHAECGVI 361
32266192  397 LRKS 400
121613439 354 LSKV 357
57237672  354 LSKV 357
222823969 342 LRLK 345
34558377  366 LRQR 369
157738407 370 LRKL 373
296274443 369 LKKS 372
152993415 368 LQKK 371
152990451 358 LTR- 360
224373183 362 LKKN 365
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