Conserved Protein Domain Family
ATC_hydrolase

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pfam14196: ATC_hydrolase 
L-2-amino-thiazoline-4-carboxylic acid hydrolase
This family of enzymes catalyzes the conversion of L-2-amino-delta2-thiazoline-4-carboxylic acid (L-ATC) to N-carbamoyl-L-cysteine. It cleaves the carbon-sulphur bond in the ring structure of L-ATC to produce N-carbamoyl-L-cysteine.
Statistics
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PSSM-Id: 464100
Aligned: 61 rows
Threshold Bit Score: 78.1959
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Snas_0568         52 DNVLYTAAV--LAAYRVLRQHEaahpdGR-GLIAWLTAAFTEPLAEQVREGTEAML----DGSPDPFAVM-----TELAK 119
BAF40040              19 REISERRAAtiSRMVDEASKR------GLdD--EFAYDAVADYGRDNAKEFRKTLKdpdsFQEFIDNFGtd--hnREIYE 88 
jgi:Amet_4120         20 rgAIEHRATwmSLMIDEAEKA------Gq-DWESMARKAIKRCGCFHGNGISEKLKdksdIKEFTELFLsd--lvKKLFE 90 
WP_014270384          22 RSQVEHRATwmALFFDEMKNA------Gi-DPEPIMRKAVYRCGEIHGAKIRENCAdpsdVREFEKTFLnk--cgQDTFH 92  Sphaero...
WP_015760332          21 reLLEHRALwlYLLTDEAAKA------Ga-DPAAFAPAAVKRCGLFQGAELVAKGGgtnsLKSLKKGLFgk--paQMVFE 91  Eggerth...
ACL05336              35 GFGLAAQLF--AAFAKEAMERL-----GPeQGEAVVKQAVQHFGRERGRSIAKAVAgmgkPLSFKNWLIYsdissDNF-- 105
goetting:CLSA_c05480   9 CTIEHHATL--FALFAKYIIEG-----LDeKGKDIIYTAVENYGQERGKRMANRAVangdDLDFINSQAYg--------- 72 
CDB02332              14 MSVHMANMY--YYLTKAVIEDF------GdEAKKSFERAIIEFGHERGKAIREEVVaaglPLTMENLDRFydipiAEGW- 84 
Q5WL21                83 PFARFAKMF--AQIAKQVVDEY------GeKGEAVIMSAVEQFGKKRGQGIAQRARsngfENTVENYLSHydmgrSELF- 153 Bacillu...
jgi:Acfer_2003        12 MFVLFARFF--SILAKNLEKEF------GeKGLEILKQSVIDWGIARGKDIARRAAqrgqKNDLDAYLPNydmerSELF- 82 
jgi:Snas_0568        120 RvegeqygaqfafEHSQD-DERGFH-----------TDVHRCGYHDFFVKHDA-AELTPVLC-AFDANWYEAIDPErhgF 185
BAF40040              89 M------------ETVKK-TDDELE-----------IDFHYCPYVTQWVRQGKnPQQIARLC-EIAMAGDHAFAAQfphV 143
jgi:Amet_4120         91 M------------DIVEL-TEDKLA-----------VEFHYCPLVSAWQKQGEsDEKMEILC-DIAMDGDRGIGESsdhF 145
WP_014270384          93 M------------DNIEA-KQDCLH-----------ISFNYCALLSAWKKLGMdDATCALLC-DIAMDGDRGIAKAm-gL 146 Sphaero...
WP_015760332          92 M------------DVKDV-QDDRFE-----------LEFHYCPLVKAWQKQGCtDEEISNLC-DWAMCGDRGIGEAy-gC 145 Eggerth...
ACL05336             106 -------------GFLPNiDNGDLV-----------LQVRNCTFIQAARQWGL-GDYGALYCkYADHAILEGYNPD---I 157
goetting:CLSA_c05480  73 -------------EWVPE--EGQMEfgvlktqpeliSNVTKCEWCRVWKKYNL-LDYGKYYCiNIDSAVFNGFNEK---F 133
CDB02332              85 -------------DLHRSyENDMKM-----------NITDSCTFATVWLEKDW-SEVGHIYC-LIDIAIREGYSDN---V 135
Q5WL21               154 -------------EFESSyKKEEIE-----------QTFTKCPLGQQWADDGT-GEYGILYCrMIDPSIAKGYNKNfdvV 208 Bacillu...
jgi:Acfer_2003        83 -------------GYDTEyGKDEIN-----------QDFDRCVFAKTWMDAGE-EKYGRIYCeNIDPAICKGYNEDlecV 137
jgi:Snas_0568        186 RFTRSTTIGLGGRICPFHF 204
BAF40040             144 KFSLEGTIADGKPVCVLRF 162
jgi:Amet_4120        146 EFELGKTIAQGNSVCEVFF 164
WP_014270384         147 TLDLSDTLAKGCKTCELNF 165 Sphaerochaeta pleomorpha
WP_015760332         146 DLDLPKTIARGDDVCHLIY 164 Eggerthella
ACL05336             158 VLKLETRHETGRDCCLFRY 176
goetting:CLSA_c05480 134 HMKATSNLSFGADHCEFHW 152
CDB02332             136 KFCPVKNILEGDPHCQslt 154
Q5WL21               209 ----HDQYVLKEGQCHFKF 223 Bacillus clausii KSM-K16
jgi:Acfer_2003       138 ----HDHIMYKDHHCTFCF 152
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