Conserved Protein Domain Family
CE4_WalW

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cd10935: CE4_WalW 
Putative catalytic domain of lipopolysaccharide biosynthesis protein WalW and its bacterial homologs
This family corresponds to a group of uncharacterized lipopolysaccharide biosynthesis protein WalW found in bacteria. Although their biochemical properties remain to be determined, members of this family is composed of a seven-stranded barrel with detectable sequence similarity to the six-stranded barrel rhizobial NodB-like proteins, which remove N-linked or O-linked acetyl groups from cell wall polysaccharides and belong to the larger carbohydrate esterase 4 (CE4) superfamily.
Statistics
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PSSM-Id: 200561
Aligned: 26 rows
Threshold Bit Score: 313.807
Created: 20-Apr-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative activeputative
Feature 1:putative active site [active site]
Evidence:
  • Comment:based on similarity to other CE4 superfamily members

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1               ##                                                                    #   
ABC62707       20 RYLLTVDTEEEFDWesefsatrhgLDHVRHIARFQEFCEnlGISPVYLVDWPIAQSelaQEIIGGACARGTAEVGIQLHP 99  Erythrobacter ...
jgi:Patl_1196  10 IFVLSIDTEEEWDWsgafpqqnadVNNVALLPSFHAHLGalGVRPTYLVDYAVADCptaASTIRTISAQQNCEIGAHLHP 89  Pseudoalteromo...
jgi:Lcho_3081  11 AFLITIDTEGDAAWaqpr---vieTRNAQYLQRFQSLCErfGFKPTYLTNYEMALApamQELGHDIIRRGTGEIGMHLHA 87  Leptothrix cho...
NP_932004       5 AFIITIDTEGDDLWqnhg---qisTKNTHYLPRFQHLCErfGFKPVWLTNYEMAMDdlyIEFAKDVIARGQGEIGMHLHA 81  Photorhabdus l...
jgi:Sfum_2250   2 KLVFSIDVEEEGLFtgeysreppgVENIRGLDRLEFVSKefGFPLTLLVSYRVARDacaRKVLLDWKDLRGAEIGAHLHH 81  Syntrophobacte...
jgi:Sros_6503  10 AFIITIDVEADDQWsrss---tvtTENAKHLPRFQSLCEkhGMRPTYLTEWAMAQDpvfQEFGASVVDRDAGEIGMHLHS 86  Streptosporang...
ZP_05127402     7 IFVLSVDTEEEWPWdsafpstdcaVSNTRKLPAFQELCQriGIRPTYFVDYAVAQDdegSAILKNIAQGGTAEVGAHLHP 86  gamma proteoba...
YP_004427764    7 LFVLSVDTEEEWEWsndfpetdcsVKNIEKLPAFQEFCEslGIKPTYFVDYAVANDtfsSDVLRTFASKKRAEIGAHLHP 86  Alteromonas ma...
ZP_03311008    14 RVVVSLDVEEEGLFsghyatsgcgVSNVSLLPRLAPLSRdlGFPLTLFCAHTVFADakaCHVLEQMRDHYGAEIGAHLHH 93  Desulfovibrio ...
ZP_07356926     8 YLVVSLDVEEEGLFggryarraprVTNTAQLSRLAPLLEr-GVRPTLFCAHSVLTDpasRAILARLRDMSGAEIGAHLHH 86  Desulfovibrio ...
Feature 1                                                                    ###                  
ABC62707      100 WVNPPfeeevna----------ynsyagNLPPDLEREKFLNLRDAIEANFNvvPQIYRAGRYGtGPSTAKMLAQaGIAID 169 Erythrobacter ...
jgi:Patl_1196  90 WCNPPyfgpatd----------esshvvNLPKEQVSQKLDVLMRRIEEQFSvkAKSFRTGRWGiDSNVLKLLTNvGITVD 159 Pseudoalteromo...
jgi:Lcho_3081  88 WHSPPehaltpdd-------lhhqpfliEYPTAVLQQKVRHLTDLLEQTFAtkMLSHRAGRWSfDSRYARTLVDcGYIVD 160 Leptothrix cho...
NP_932004      82 WNNPPlvpltddd-------mrykpyliEFPKEQIRAKIDLMTKLLEDKLQikMLSHRAGRWAfNEYYAELLVEyGYQVD 154 Photorhabdus l...
jgi:Sfum_2250  82 WSTPPfdklpyp----------epvpadLLPPALLRAKLENLLDALKTNLGvtARSFRMGRFDiGTQVPKLLPElGLLTD 151 Syntrophobacte...
jgi:Sros_6503  87 WTTPPsvpltsmd-------hvhhpfliEFPENVIREKVRMATEVLEDMFQvsMVSHRAGRWAlDERYAKILVEhGYLVD 159 Streptosporang...
ZP_05127402    87 WCNPPfygktge----------aeshivNLPKEQVASKLDALHELLQDRLGvrPRSFRSGRWGiNSETLQLLIDrGYTVD 156 gamma proteoba...
YP_004427764   87 WCNPPffgktde----------akshvvNLPKDHVKAKLDHLIERLITNIGqaPMSFRSGRWGiNGSTLELLVErGFKVD 156 Alteromonas ma...
ZP_03311008    94 WSTPPsspldpph-------egqptrtdKLPRDLLRQRLATLLDAGREFQGapLTSFRMGRWDlKDCVRPLLSEaGIKVD 166 Desulfovibrio ...
ZP_07356926    87 WNTPPldldshaggqsdmadvtnsvpaaSVPAALMAAKLGTLFRVGEDFQGapLTSFRMGRWDlHRAHWPLLARaGVLCD 166 Desulfovibrio ...
Feature 1                                                                                         
ABC62707      170 TSVrskfn-------yakgAGPDYGLHPLKPWWvge--------dhKLLELPVTSVFwgllrrsadrl----yplatkie 230 Erythrobacter ...
jgi:Patl_1196 160 SSVypf----------ysnDYFSCLGAPSLPYWpdlnnplvssqqrDIFELPVTVGFnrpnfsrwndihtkfasppyswt 229 Pseudoalteromo...
jgi:Lcho_3081 161 CSVtptvswrdtpgdpaqhGGTDFRPFPSQAYFmdldqi-drpgrsPLLELPMTIRSsrrswar-----------hlpaa 228 Leptothrix cho...
NP_932004     155 CSVtprvnwrftkgdpngnGGTDYRHFPSYAYFmdlqni-akegdsPLLEVPMSIQYkhpplmn------------flkq 221 Photorhabdus l...
jgi:Sfum_2250 152 SSIvplr---------rtaGGPDHFMAPCEPYRlegsd----grtpSVLEVPLTMIPlfprtrnavyrq--ssflpprvr 216 Syntrophobacte...
jgi:Sros_6503 160 CSVtphvswsgnrgapagrGPRDYSDFPRNAYFvdleci-gregdsPLLEVPMTIVPspwrqswkgv-----drlisrss 233 Streptosporang...
ZP_05127402   157 SSVypf----------yenDYFSCEGSPLTPYYpdldkvltagdqrKLMELPVSAGFnrgnfdraqrihkalssapaswl 226 gamma proteoba...
YP_004427764  157 SSVypf----------yenTYFSCKNRDSTPYWpsfenadvegaqrNLMELPITAGFnrshfkyadnihtflaksplrla 226 Alteromonas ma...
ZP_03311008   167 SSVcplr---------hfpGGPDHFLAPADPYWvegw------qgaPLLEAPITQIPlhpalar-----------lwyra 220 Desulfovibrio ...
ZP_07356926   167 ASVrplhcak--tgadgvaAGPDHFNAPSDPYWvpv-------egkHIFEVPLTVTPllrplpkmlra---lpdgpdswg 234 Desulfovibrio ...
Feature 1                                                       #                                
ABC62707      231 pmAGLLSKLSLleRIALTPEGVSVEEALRGVDIAVddGLPIIVLSFHSPSLAPGyTPYVKNDADVDALYDWFRQVCGYL 309 Erythrobacter l...
jgi:Patl_1196 230 rfNGIAWHTHLlrKQYLCPELSAPKDMLSLCETVInkGYTVLHMYMHSSSLLDNnNSLLGNRNAYEFLSESITEVITTL 308 Pseudoalteromon...
jgi:Lcho_3081 229 feRLPRIGPKLskARWLRPGRGNLAQMQQLVQDMVadDAPYIEFMLHSSEFMPGgNPTFVSEADIEALYSDLEQLFETI 307 Leptothrix chol...
NP_932004     222 kyDSLRGKPRSpsVNWLRPKGGNLEQMKKVVQQTLaeGSDYIEFMLHSSEFMPGgSPTFKNEQQIELLYQDLEALFNYL 300 Photorhabdus lu...
jgi:Sfum_2250 217 dfLLTAYRHAA--VVGVHPAWFSLSAMKLAANLHRarGGCVLCMFLHSSEVHPGaTPKFRTESDVRRLVDKIRAFLAWL 293 Syntrophobacter...
jgi:Sros_6503 234 taKRLMNRVSPe-VKWMRPDGRNRTDLLRIAAQAPaaACDHVEFMLHSSEMMPGgSPYFRTGRSIEGLFDDMEELFEFA 311 Streptosporangi...
ZP_05127402   227 raVGLLWHTRLlrKLYLSPELTEANDMNSLVDQCLnnGQPVIHMFLHSSSLVDHvTGLMDTDNAYDVITDRIAQTLKHL 305 gamma proteobac...
YP_004427764  227 kpVGLLWHTNIlrKLYLSPELTDSTSMKMLVNICLekQYPVIHMYLHSSSLLDGvTGLLQVDNAYQRICGRMSEVIKHL 305 Alteromonas mac...
ZP_03311008   221 cpAASRDKFHFwgVLSPNPFWHAPRIMRWSARLHRqrGGQVLSLFWHSSEMLPGgSPHVPDQKAADAVLERIHTFLSWL 299 Desulfovibrio p...
ZP_07356926   235 raVRASLRHWG--ALALLPVEHPFWAIRAVTSLFAarGGRVLSLTWHSSEMLPGgAPHLPDAASVERLMTKIEAYLDWL 311 Desulfovibrio s...

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