1WF1


Conserved Protein Domain Family
RRM_RALY

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cd12604: RRM_RALY 
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RNA recognition motif (RRM) found in vertebrate RNA-binding protein Raly
This subgroup corresponds to the RRM of Raly, also termed autoantigen p542, or heterogeneous nuclear ribonucleoprotein C-like 2, or hnRNP core protein C-like 2, or hnRNP associated with lethal yellow protein homolog, an RNA-binding protein that may play a critical role in embryonic development. It is encoded by Raly, a ubiquitously expressed gene of unknown function. Raly shows a high degree of identity with the 5' sequences of p542 gene encoding autoantigen, which can cross-react with EBNA-1 of the Epstein Barr virus. Raly contains two distinct domains, an N-terminal RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain), and a C-terminal auxiliary domain that includes a unique glycine/serine-rich stretch.
Statistics
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PSSM-Id: 410016
Aligned: 6 rows
Threshold Bit Score: 161.735
Created: 19-Sep-2011
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1WF1_A        27 NSRVFIGNLNTAlVKKSDVETIFSKYGRVAGCSVHKGYAFVQYSNERHARAAVLGENGRVLAGQTLDINMAGEPKP 102 human
NP_991173     20 NSRVFIGNLNTAvVKKSDVETIFSKYGRVLGCSVHKGYAFVQYANERHARGAVIGENGRVLAGQTLDINMAGEPKP 95  zebrafish
KYO42248      27 NSRVFIGNLNTAvVKKSDVETIFSKYGRVVGCSVHKGYAFVQYSNERHARAAVLGENGRVLAGQTLDINMAGEPKP 102 American alligator
OCT62843      20 NSRVFIGNLNTAvVKKSDVESIFSKYGRVVGCSVHKGYAFVQYMNERHARGAVIGENGRVLAGQTLDINMAGEPKP 95  African clawed frog
XP_006007886  22 NSRVFIGNLKTTiVKKSDVETIFSKYGRVVGCSVHKGYAFVQYTNERHARAAVIGENGRVLAGQTLDINMAGEPRP 97  coelacanth
XP_007907478  20 NSRVFIGNLNTAvVKKSDVETIFGKYGKIVGCSVHKGYAFVQYTNERTARVAVAGENRRVLAGQTLDINMAGEPKP 95  elephant shark
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