2EBM


Conserved Protein Domain Family
RWD_RWDD1

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cd23816: RWD_RWDD1 
RWD domain of RWD domain-containing protein 1 (RWDD1) and related proteins
RWDD1, also called DRG family-regulatory protein 2 (DFRP2), or PTD013, interacts with DRG2 and protects DRG2 from proteolytic degradation. It is an androgen receptor-interacting protein that functions as a coactivator of androgen-dependent transcription.
Statistics
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PSSM-Id: 467652
Aligned: 19 rows
Threshold Bit Score: 120.86
Created: 14-Aug-2017
Updated: 27-Apr-2023
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2EBM_A        11 YGEEQRNELEALESIYPdSFTVLSe-nPPSFTITVTSEAGen------deTVQTTLKFTYSeKYPDEAPLYEIFSQENl- 82  human
XP_002128914   4 YEEEQRDELEALESIYPdSFTIVSt-dPTAFSLKISTEESilda---dkaIISVTLKFTYAkKYPDEAPLFEVLEEENfp 79  vase tunicate
ELT96772       4 YQEEQQNELEALESIYPdELTVVAmepFPCFQLPISTEDDs--------eCVKCVLQFTYTaKYPDEAPLMEIAESENv- 74  Capitella teleta
EFX68207       7 YKEEQLGEIFSLESIYPdELEILEeepFHQFKLQVKSEGHdee----egiGYACDLKFTYTpTYPEEIPMIEIMDDVGl- 81  common water flea
XP_013383262   4 YKEEQDNEIEALESIYPdEIKVLSt-ePYTFTVDINITDSpnen--hedeSVSITVQFTYTpSYPDEGPLIEIVNANNl- 79  Lingula anatina
XP_002741801   4 YQEEQNNEIEALASIYPdEFTALSe-dPHRFKVIISSENTdedg---edaAITITLQFTYTpRYPDEGPVMEVISADNl- 78  Saccoglossus ko...
XP_030850599   4 YKEEQVNEIEALESIYPdELSVLTtepCHVFQLTVAAEEEegedeeeekgQLSVTLKFTYTpTYPEEAPIFEVIFDDDdl 83  purple sea urchin
OXA50104       3 YLEEQRSELEAIEAIYPiEFKLVSd-sPITFMISVKSETYeeg----geeGLACTLKFVFTpKYPEQVPDIEIIDDEEee 77  Folsomia candida
RWS04547       6 CLEEQINEIEALESIYCnEITVISkstPIKFSINVNGDNStd-------sELELQLTFTFTrNYPEEAPEIEVSLAGDnf 78  Dinothrombium t...
XP_009012341   4 LKEDQSNELEVLESIYTnELTIISrepLISFLLTIATQIEkvd-----meDVEICLKFTLPeNYPDEVPAVEIISHSNl- 77  Helobdella robusta
2EBM_A        83 ------eDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQIK 126 human
XP_002128914  80 ------fENTGEKLEVLIEEQIEENLGCVMVFTIMSAVQEFLNQEDDRFK 123 vase tunicate
ELT96772      75 ------dDELLTVLLEYMKEQVRENLGMVMVFTIVSSVQERLISFLEDAE 118 Capitella teleta
EFX68207      82 ------dDEQLERLKDRLEKEAEDNLGMVMIFSLVSTANEWLNNEWDAEL 125 common water flea
XP_013383262  80 ------dDQETDSLLQFMQSQVEENLGMVMVFSIVSATQEKLTEMREERK 123 Lingula anatina
XP_002741801  79 ------dEEDISSILQLLQEQVEENLGMAMVFTLVSAVQERLNEKVDEIK 122 Saccoglossus kowalevskii
XP_030850599  84 ------aQDFEQEIRDLVLAQIEENLGMAMIFAIVSASQEFLNERIDDIK 127 purple sea urchin
OXA50104      78 ednsnlePEDILDLTEFLRQQANENVGMAVVFTIVSAAIEWLNNKWDSIL 127 Folsomia candida
RWS04547      79 ------dENDEQQLLELLNNEANNNLGMVMVFTLVSVATEWLNTKRDQQK 122 Dinothrombium tinctorium
XP_009012341  78 ------eESYVEVLTEMIIRLAEENVGTVMTYNIVTALQDKLIEIVETVA 121 Helobdella robusta
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