6Q56


Conserved Protein Domain Family
TrmK

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pfam04816: TrmK 
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tRNA (adenine(22)-N(1))-methyltransferase
tRNA_MT is a family of bacterial tRNA (adenine(22)-N(1))-methyltransferase enzymes with a Rossmann-like fold. This enzyme carries out the function of N1-adenosine methylation at position 22 of bacterial tRNA.
Statistics
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PSSM-Id: 428139
Aligned: 11 rows
Threshold Bit Score: 229.509
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6Q56_D        23 MADIGSDHAYLPSYAVLNHKASGAIAGEITDGPFLSAKRQVEKSGLNSHIsvrQGDGLEVIKKGE-A-DAITIAGMGGAL 100 Bacillus subtil...
P75427        20 FYDIGCDHGYLARELVQQNPSLVGVNSDISANALGAAKGLLKDHTNMHFI---TSDGFDLLPNLNlDpAVGVIAGLGGLK 96  Mycoplasmoides ...
Q9RXN4        22 HADIGTDHARLPLRLVRGGRVSRCVAVELNPGPLALARRMVARARLTEQIdvrQGDGFAPIQPGE-L-GSASVTGMGAYT 99  Deinococcus rad...
1_pfamImport   1 IADIGSDHAYLPCFAVKNQTASFAIAGEVVDGPFQSAQKQVRSSGLTEHIdvrKGNGLAVIEKKDvI-DTIVIAGMGGAL 79 
Q9KD40        23 LADIGSDHAYLPCYLCLKGVVEFAIAGEVNEGPYQSAVEQVQKVNLGHVIsvrKGDGLAVIRADDqI-DTVTIAGMGGTL 101 Bacillus halodu...
Q9CGM4        23 LADIGSDHAYLPTYLMQKLVIDFAVAGEVVKGPFEIAKNHVSEADLSDRIevrLANGLGAIENTDkI-DTIVIAGMGGIL 101 Lactococcus lac...
Q8DNY3        19 LLDVGSDHAYLPIELVERGQIKSAIAGEVVEGPYQSAVKNVEAHGLKEKIqvrLANGLAAFEETDqV-SVITIAGMGGRL 97  Streptococcus p...
Q8DT98        27 LLDVGSDHAYLPIYLLEQGLIDFAVAGEIIKGPYESAVANVSESELSGQIavrLADGLAALNDNDdI-DLITICGMGGRL 105 Streptococcus m...
Q2FY13        20 IADIGSDHAYLPIYAIQNHLCECGIAGEVIQGPFQAAVKNVAANQLVDRIdvrLGDGLSVIQPEDvI-DNITICGMGGPL 98  Staphylococcus ...
Q9PQE1        20 VVDVGSDHAYLAKILLVNNKAQHVTNIEVNQGPLENGINNLTKNNLLKRTtniLNDGFKGLILEQtF-DYCVIAGMGATS 98  Ureaplasma parvum
Q97JI1        20 AADIGTDHAYLPIYLIKNNLCKRFIASDVNAGPLKKAINNINKYKLEDKIecrLGSGLNVLKL-EeV-DVVVIAGMGGNL 97  Clostridium ace...
6Q56_D       101 IAHILEAGKDKLtgkERLILQPNIHAVHIREWLYKERYALIDEVILEEDGKSYEVLVAEAGDRDAay-dgISLSAGMLVG 179 Bacillus subtil...
P75427        97 IMQILAQHNNFL---KHFVLQPQSNIIELRRFLSANQWTITTETLVEERGFIYLVLAVDKTKAQTq----YLTEEQMILG 169 Mycoplasmoides ...
Q9RXN4       100 IRGILDRAGERLpp--aLVLQPNDSPLWLRTWARENSYHLRAERLLPG-YWAYPVLRLERAEGPDpayadLPAAAALRYG 176 Deinococcus rad...
1_pfamImport  80 IRTILEEGAAKLagvTKLILQPNIAAWQLREWSEQNNWLITSEAILREDNKIYEIMVLAPSKKPVa----W-TKQEIFFG 154
Q9KD40       102 ISTILEEGKRNLqtvRRLILQPNVHGKAIRQWLSDNGWRLQAEAILEEDEKIYELLIAERGSDEDl---yVSKELDLLVG 178 Bacillus halodu...
Q9CGM4       102 ISEILEAGKEKLghvKRLILQPNNHEESLRQWLVNHQFVIKKEEILLEAGKFYEIIVAEPLSKLMt---eKLSVNDLTFG 178 Lactococcus lac...
Q8DNY3        98 IARILEEGLGKLanvERLILQPNNREDDLRIWLQDHGFQIVAERILEEAGKFYEILVVEAGQM-------KLSASDVRFG 170 Streptococcus p...
Q8DT98       106 IADILAAGSDKLnsvKQLILQPNNCEDDLRSWLVANDFMIKAEKMVKDRHKYYEILVVEKGKI-------TLSDKDLRFG 178 Streptococcus m...
Q2FY13        99 IAKILKDGQDKLsqhPRLILQSNIQTENLRQTLQQLNYEIIDEIIMEEKGHIYEIVVAEYSTELIe-----LSSDELKFG 173 Staphylococcus ...
Q9PQE1        99 IIEILEQNKNQi---KNYILQPNTQSYKIRKYLNNHSYQIKVEHIFVEKKIFYEIIICSKTINVP-----KLIEKDYYIS 170 Ureaplasma parvum
Q97JI1        98 IRDIIEERLDIFkklKYAVLQPVQNPEILREYLIKRGFNIIEEQLCIDESKYYEIIKVCYDSKIEd-----kDDVYYEIG 172 Clostridium ace...
6Q56_D       180 PFLAKEKNAVFLKKWTQELQHtqsiyeq-isqaadTEQNKQKLKELADRM-ELLKE 233 Bacillus subtilis subsp. subtilis str. 168
P75427       170 PHLVNFTDKQMLVKYYNGLLK--------------NFTARLNPSQFDSQViHVLNK 211 Mycoplasmoides pneumoniae M129
Q9RXN4       177 PLLLRKGPALLRARIEADIERltpv-------aapGREAWAELAAAREALaVVDAG 225 Deinococcus radiodurans
1_pfamImport 155 PCLLKDQSAIFKSKWRHEANTwqniiqtisnnqpvSPENQAKIRELEHKI-ALVE- 208
Q9KD40       179 PYLRKERNAAFQKKWTAELISwkrvlsq-lnkakpSEELEAKKIELQKNI-SLIEE 232 Bacillus halodurans
Q9CGM4       179 PFLSKEKSTVFQQKWQKELNTlnkii-----arlpEEQAE-KRQEVLNQI-ARIEE 227 Lactococcus lactis subsp. lactis
Q8DNY3       171 PFLSKEVSPVFVQKWQKEAEKlefal-----gqipEKNLE-ERQVLVDKI-QAIKE 219 Streptococcus pneumoniae R6
Q8DT98       179 PFLRQERSSIFKERWRKELAKlelal-----tkvpAKK-KADNMFLSTKI-EQIKE 227 Streptococcus mutans
Q2FY13       174 PKLLNNKNEYFIKKWQRELEAlyhik-----sklnTEQHHQRLAQINDEI-AVIEr 223 Staphylococcus aureus subsp. aureus NCT...
Q9PQE1       171 SQMHKDSLNLYFKFLKRRYEYlkald-----islvSENIVKEYEYIKEFInEKNGY 221 Ureaplasma parvum
Q97JI1       173 DKLIDMKHPLLKEYINYKIRKydkiyk---niseeSLNALSRKNELSIKI-RKLKE 224 Clostridium acetobutylicum
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