Conserved Protein Domain Family
PRK12645

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PRK12645: PRK12645 
monovalent cation/H+ antiporter subunit A; Reviewed
Statistics
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PSSM-Id: 237155
Aligned: 53 rows
Threshold Bit Score: 1117.7
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
297584674   1 MSTLHFIPLLPFIVAVLIPFLYKKFRHIHTGWFLLPVPLIIFIFMLQYLPFSGDPfQEVSYTFDWVPSLDIAYTVYVDGL 80 
305675747   1 MQLLHFAILSPFLFAFIIPILAKYAKRVHTGWFVLILPVLLFIYFLPMIRMTQSG-ETLRSVFEWIPSLGINFTVYIDGL 79 
154687269   1 MQLLHFAILAPFLFTFIVPFLYKRVKQVHTGWFVLIVPVVLFVYFISKLPVTMAG-ETVRYAAEWIPSLGINYTVYLDGL 79 
52787040    1 MTSLHIAILSPFALAFLIPLLAKNVRKIHTGWFVLFLPVLLFIYFFRMIKMTADG-GTLKAVLEWIPSFGINFTAYVDGL 79 
52081655    1 MTSLHIAILSPFALAFLIPLLAKNVRKIHTGWFVLFLPVLLFIYFFRMIKMTADG-GTLKAVLEWIPSFGINFTAYVDGL 79 
157693582   1 MQLIHFAILSPFLLAFVVPFLFKYVKRIHTGWFVLILPILLFSYFVQMMTMTSNG-RTLFSQVEWIPSLGMNFTVYVDGL 79 
229918331   1 MSLLHLAILLPLLAAPFIPLLFRGMKQIHTGWFVLIVPVVLVTYFAGFIPITSAG-DVVTETIAWMPSLGINFTAYVDGL 79 
172057706   1 MSLLHLAILLPLLVSLFIPLLYKKIRSVHTGWFVLLVPLTLVAYFSQFLSQTMAG-KTVVATMKWIPSLDINFVAYVDGL 79 
138896530   1 --MLNLAIVSPLIFALFIPFLYKYVRSIHTGWFVLPLPVLLFVYFIQHLPLEPYG-----QTIPWIPSLGMDFQVYMDGL 73 
239828197   1 MSMLHWAIISPFLLAIFVPFLYKYVRPIHTGLFILPLPIILFIYFIQYISITEKY-GTQIETVPWIPSLGLDFTAYVDGL 79 
297584674  81 SLLFTLLISGIGTLVVLYSIYYIAnkKDEPLNNFYVYLMMFMGAMLGVVLSDNLIVLYVFWELTSLSSALLIGYWFHKER 160
305675747  80 GLLFALLITGIGSLVTLYSIFYLSk-EKEQLGPFYVYLLMFMGAMLGVVLVDNVMVLYMFWELTSLSSFLLIGYWYKREK 158
154687269  80 GLLFALLITGIGSLVTLYSIFYLSk-DKEKLGPFYVYLLMFMGAMLGVVLVDNVIVLYMFWELTSLSSFLLIGYWHKRKK 158
52787040   80 GLLFALLITGIGSLVVLYSIYYLSk-EREQLGPFYVYLLMFMGAMLGVVLVDNVIVLYLFWELTSISSFLLIGYWYKREK 158
52081655   80 GLLFALLITGIGSLVVLYSIYYLSk-EREQLGPFYVYLLMFMGAMLGVVLVDNVIVLYLFWELTSISSFLLIGYWYKREK 158
157693582  80 SLLFALLITGIGALVVLYSIFYLSk-EKEQLGSFYTYLLMFMTAMLGVVLSDNMVVLYLFWELTSISSFLLIGYWYKRDR 158
229918331  80 SLLFALLITGIGALVVLYSIYYLNk-DKESLGHFYVYLLMFMSAMLGVVLSDNMIVMYMFWELTSISSFLLIGYWYEKER 158
172057706  80 GLLFALLITGIGSLVVLYSIYYLDa-KKEALHNFYVYLLLFMTAMLGIVLSDNMIVMYLFWELTSISSFLLIGYWYERER 158
138896530  74 GLLFSLLITGIGSLVVLYSIYYLPk-EKEKLGHFYVYLLLFMGAMLGVVLSDNAMALYLFWELTSFSSFLLIGYWNERER 152
239828197  80 GLLFALLITGIGSLVILYSVYYLSk-EKEKLHHFYVYLLLFMGAMLGVVLSDNLMVLYLFWELTSLSSFLLIGYWNERER 158
297584674 161 SRYGAQKSMMITVAGGFAMLAGFTLLYLMA-GTFSIRGIIDVADQIAASPYFIPAMLLILAGAFTKSAQFPFHIWLPDAM 239
305675747 159 SRYGAAKSLLITVSGGLCMLGGFILLYLIT-DSFSIREMILQVQLIAGHDLFIPAMILILLGAFTKSAQFPFYIWLPDAM 237
154687269 159 SRYGAEKSLLITVGGGLCMLGGFILLYLMT-DSFSIREMVNQVHIIAGHPFFIPAMVLLLLGAFTKSAQFPFYIWLPDAM 237
52787040  159 SRYGATKSMLITIFGGLSMLGGFILLYTIT-GSFSIREMINQVDLISGHGFFIPALVLVLIGAFTKSAQFPFYIWLPDAM 237
52081655  159 SRYGATKSMLITIFGGLSMLGGFILLYTIT-GSFSIREMINQVDLISGHGFFIPALVLVLIGAFTKSAQFPFYIWLPDAM 237
157693582 159 SRYGATKSLLITVFGGLAMLGGFILLYLIT-DSFSIREAVNQLQLIMASPYFIPAMILILLGAFTKSAQFPFYIWLPDAM 237
229918331 159 SRYGAQKSMLLTVFGGLSMLGGIVLLESMV-GSYSIRDMVANSGVIAESPFFLVAMVLILLGAFTKSAQFPFHIWLPDAM 237
172057706 159 SRYGAQKSMLITVFGGLSMLGGISLLSLLS-GSFSIRESLATVGTYSGDPLFTVSLVLFLLAAFTKSAQFPFHIWLPDAM 237
138896530 153 SRYGAQKSMLITVLGGLSLLGGFLLLSVMSgGSYSIRDWIDMADAWPQHPLFLPAMLLILLGAFTKSAQFPFYIWLPDAM 232
239828197 159 SRYGAQKSMLITIFGGLALLGGFLLLSVMG-GTYSIRELAAQSSELAGHSLFVPALLLILLGAFTKSAQFPFYIWLPDAM 237
297584674 240 EAPTPVSAYLHSATMVKAGIYLVARLTPVFGGQAEWFWIITSFGLFTLLWGSVSAVRQKDLKGILAFSTVSQLGLIMSLL 319
305675747 238 EAPTPVSAYLHSATMVKAGIYVIARFSPIFAFSAQWFWIVSLVGLFTMVWGSFHAVKQTDLKSILAFSTVSQLGMIISML 317
154687269 238 EAPTPVSAYLHSATMVKAGIYVIARFSPVFAFSPVWFWTVASVGLITMVWASFNAMKQTDLKAILAFSTVSQLGMIVSML 317
52787040  238 EAPTPVSAYLHSATMVKAGIYIVARFTPVFAFSGEWFWIVSLTGIVTLFWGSFNAVKQTDLKSILAFSTVSQLGMIMSML 317
52081655  238 EAPTPVSAYLHSATMVKAGIYIVARFTPVFAFSGEWFWIVSLTGIVTLFWGSFNAVKQTDLKSILAFSTVSQLGMIMSML 317
157693582 238 EAPTPVSSYLHSATMVKAGIYLVARFSPIFAISEVWFWTISIVGLVTLFWGSFHAVRQNDLKAILAFSTVSQLGMIMLML 317
229918331 238 EAPTPVSAYLHSATMVKAGLYLVARMSPVFQESSVWLWTIAGVGMFTMFWGSFNAVKQTDLKGILAFSTVSQLGLIMSLL 317
172057706 238 EAPTPVSAYLHSATMVKAGLYLVARMSPIFAETPLWFYLVSSVGMFTLFWGSLNAVKQVDLKAILAYSTISQLGLIMSLL 317
138896530 233 EAPTPVSAYLHSATMVKAGIYLVARFTPIFAVSSLWVWLVMGIGMATLCWASFHAARQTDLKGLLAYSTVSQLGLIMSLL 312
239828197 238 EAPTPVSAYLHSATMVKAGIYLVARLTPIFAVSPLWIWLVGGIGILTLFWASFHAPRQTDLKGILAYSTVSQLGLIMSLL 317
297584674 320 GMGSAAFHYGLDDGqSLYTVAILAAVFHLFNHATFKGSLFMVVGIIDHETGTRDIRKLGGLMAIMPVTFTISLIGIASMA 399
305675747 318 GVSAAALHYGHT---EYYTVAAMAAIFHLINHATFKGSLFMAVGIIDHETGTRDVRKLGGLMAIMPITFTISLIGTFSMA 394
154687269 318 GAGAAALHYQHS---EYFTAAVTAAVFHLINHATFKGSLFMAVGIIDHETGTRDIRRLGGLMALMPVTFTVSLIGTFSMA 394
52787040  318 GVGAAALHFQHF---EYYMVAVIAAIFHLINHATFKGSLFMAVGIIDHETGTRDIRKLGGLMTIMPITFTITLIGAFSMA 394
52081655  318 GVGAAALHFQHF---EYYMVAVIAAIFHLINHATFKGSLFMAVGIIDHETGTRDIRKLGGLMTIMPITFTITLIGAFSMA 394
157693582 318 GVGAAAIHENEP---AYFGAAVLAAIFHLINHATFKGSLFMAAGIIDHETGTRDIRKLGGLMTIMPITFTITLIGTFSMA 394
229918331 318 GLGAAALHYDGMDD-NIFMVATIAAIFHLINHATFKGSLFMMVGIVDHETGTRDIRKLGGLMTVMPISFTVAVIGSLSMA 396
172057706 318 GLGAAALQVDIIPD-SLYTVATVAAVFHLINHATFKGSLFMMAGIVDHETGTRDIRKLSGLSQLMPVTFTIATIGTLSMA 396
138896530 313 GAGALAFHGDPSDR-RLYMAAVVAAVFHLINHATFKGSLFMTAGIVDHETGTRDIRRLGGLLSFMPITFTIAVIGSLSMA 391
239828197 318 GVGALSFHYDTIDD-NIYIIATVAAVFHLINHATFKGSLFMVVGIVDHETGTRDVRRLGGLMTVMPITFTVALIGALSMA 396
297584674 400 GLPPFNGFLSKELFFEGVLNATAVDIFSGQFLMAIFPVVAWIASVFTFVYSANMLFQTFTGKHKPDELPKHAHEAPVGML 479
305675747 395 GLPPFNGFLSKEMFFTSMLRVTHFDLFNVQTWGILFPVLAWIGSVFTFIYSMKLLFKTFRGSYQPEQLKKQAHEAPVGML 474
154687269 395 GLPPFNGFLSKEMFFTSMLRIAHADIFSLDTWGVLFPVLAWIGSVFTFIYSMKLFFRTFSGARKPDQLEKTPHEAPLGML 474
52787040  395 GLPPFNGFLSKEMFFTSMLRITNFNLYNADTWGFLFPVLAWIGSVFTFIYCMVLLFKTFGGKYQPEKLEKQAHEAPIGML 474
52081655  395 GLPPFNGFLSKEMFFTSMLRITNFNLYNADTWGFLFPVLAWIGSVFTFIYCMVLLFKTFGGKYQPEKLEKQAHEAPIGML 474
157693582 395 GLPPFNGFLSKELFFTSMIRISEISFTDISTWGAIFPAIAWLASVFTFIYSMMLLFKTFRGHLQLDQLEKKPHEAPIGML 474
229918331 397 GLPPFNGFLSKEMFLKATTKVFSADFFALDTIGILLPVIAFVGSVFTFIYSIMLFTRTFMGKAKFDQLPKQPHEAPIGML 476
172057706 397 GVPPFNGFLSKEMFLTGVLQVSESGLFHLDTFGLLFPFFAVVGSIFTFVYSILIVYRTFLGPKQLDKLPKKPHEAPIGML 476
138896530 392 GVPPFNGFLSKEMFFAAMVQVANAHWFSLDVWGILFPVLAWVGSVFTFLYSLLFVGKTFLGAPKPSEWPKQPHEAPVGML 471
239828197 397 GMPPFNGFLSKEMFFTAMVRVLQADIFSLDTWGILFPVIAWIASVFTFLYSFLLLGRTFFGSYQPEQLPKKPHEAPLGML 476
297584674 480 ISPAVLAAMVIFFGLFPNLLAYTIIEPAMQAIIPGLTApgeqfYINIYHWHGINTELLMTLGVVFIGIAIFLNMRKLEQT 559
305675747 475 VSPVILVALAVSLFFFPNILSYSLIEPAMNSIYPTLLDshekfHVHISQWHGLNTEVLMTAGIIVIGTIGYLSLNKWKGI 554
154687269 475 ISPVILAACAVSLFFAPNVLSYSLIEPAMNSIYPALLTggdtfHVHISQWHGVTAELMMTLGIIIVGTIGYVTLSKWERL 554
52787040  475 ISPIVLVSLVVIFFFFPNILSYSIIEPAAASIMPTLLDgdekfKVHIYMWHGFSTELYMTIGVVALGVLAYLTLSKWRKV 554
52081655  475 ISPIVLVSLVVIFFFFPNILSYSIIEPAAASIMPTLLDgdekfKVHIYMWHGFSTELYMTIGVVALGVLAYLTLSKWRKV 554
157693582 475 IPPIILAALVVTFFFFPNILAYSVIEPAIAAIIPDAIDpgkrfVVKIEAWHGFQPELYMTMGVVALGIIGYLTLSKWRPI 554
229918331 477 ISPVILALLVVGLGFFPNVLSNSLIKPAVESIYPTLVAqgqdvKVDIYFWHGLTPELYMTIGVILLGSLLFWQMGKWMGI 556
172057706 477 IPPLVLVSLVILIGLFPNLLSNTLIRPAAEAILPKVIAnggtiPVEIKLWHGFNLELFLTVLIISAGTVLFLTLPKWRSL 556
138896530 472 VAPVVLAVLVIGFGLFPNVLSNAVIAPAADAIVNGVFRqe-glSVHISHWHGWTIEVWMTIGVIVLGVLLYRTFDSWKRV 550
239828197 477 IAPVVLALLVIVFGLFPNMLSHTLIAPAADAILTGPFRte-gsALHISHWHGWTIELWMTIGVIVLGTMLYKTFPRWKSL 555
297584674 560 AFYAGERDPLNWFYDNGLTGLISGAQKVDGVQMTGKLRHYFMYMFVFLIlVIGYALITTGSIAIDFSETAGISPYLFLIV 639
305675747 555 YKLFPSKLTLNRLYDKLVTLMEKGSYRITKQYMTGFLRDYLLYIFAGFIiLMGGAFVIKGGFSFTTEGMAKIGVYEIILT 634
154687269 555 YGLFPKKLTLNKLYDAVTGSMEKRSYQLTSSYMTGFLRDYLLYIFAAFIiLIGTAFVTKGGFSMTAKGMAEIGLYEIVLS 634
52787040  555 YGLFPETLTLNKLYDSSLSGLEKGSNKITRTYMTGFLRDYLVYVFVFFIvIIGGSLAVTGGFSYDVKGNASIGVYELVLS 634
52081655  555 YGLFPETLTLNKLYDSSLSGLEKGSNKITRTYMTGFLRDYLVYVFVFFIvIIGGSLAVTGGFSYDVKGNASIGVYELVLS 634
157693582 555 YNIFKKKWSFNSLYDRSLIGLEKGSYRLTSSYMTGFLRDYLVYVFGFMIiVLGGVMFYQNAFSFNMKNAAPIGTYEVILS 634
229918331 557 YNRIPHRLTLNGMYDGTLVWSNKAAYRFKDNYMTGFIRSYLIYIFVFLSgMMLFSIWWFDMYRFSFENLAEIAPYEYVLG 636
172057706 557 YHRMPKQVSLNHQYDALLRRGERTSTAIHDTVMTGYMRSYLVYIFGFIVvLVLSSLYFLDAFRFDVNPLSTVHAYEVVLV 636
138896530 551 YGAFSQRLSLNHLYDTVVRQMEERSHSLTSRYMTGYVRTYFLYILSAMLaLLIVTIVLKVDGEFSLSHLADVGVHELMLV 630
239828197 556 YQKFPKRLSLNHLYDRMVDGMERGSYTLTESYMTGYIRTYFVYILSAFIaLLAFSILVKGKWHISTDHLAPVGAHELVLS 635
297584674 640 AATTLATVAIPFVSKRIPAIVLLGIVGFLVALLFVVLRAPDLALTQLLVETVMVVLLLLAFYHLPELKSESFKPVFKVTN 719
305675747 635 LVMISATAATVFAGSRLTAIISLGVVGYALALFFVIFRAPDLALTQLVIETISVALFLLCFYHLPKLRLKKKTRTFRMTN 714
154687269 635 LVMVSATIATVFAKSRLTAIISLGVVGYTLALFFVIFRAPDLALTQLVIETISVALFLLCFYHLPKMRRKKKTRTFRMTN 714
52787040  635 AVMIAATFTTVFARSRLTAIIGLGVIGYTLALFFVIFRAPDLALTQLIIETISVALFLLCFYHLPKLRFKPKSARFRVTN 714
52081655  635 AVMIAATFTTVFARSRLTAIIGLGVIGYTLALFFVIFRAPDLALTQLIIETISVALFLLCFYHLPKLRFKPKSARFRVTN 714
157693582 635 LVMIAATLTTVFARSRLTAIIGLGVMGYTLSLFFVIFRAPDLALTQLIIETISVALFLLCFYHLPQLSMKQKTRKFKMTN 714
229918331 637 AVVMLAALAILFMKSRLPSIILLGVVGYGVALFFVFFGAPDLALTQLVIETVSVALFLLVFYHMPDISKKEVRMRFKVGN 716
172057706 637 LVLVGSALSITFARSRLTSIILLGVVGYTVALFFVLFRAPDLALTQLVIETVSVALFLLVFYHMPEISRKEERIKFKLGN 716
138896530 631 LAALVGTVTTLVAKSRLVAIIALGSVGYTVSLFFVLFRAPDLALTQLVIETISVALFLLCFYHLPKLSRHEKGVRFRLGN 710
239828197 636 LIIIAGTITTIMAKSRLTAIIALGSVGYTVTLFFVLFRAPDLALTQLVIETISVSLFLLCFYHLPQLSRHEKGIRFRLGN 715
297584674 720 LLISIGVGTVVTLVALSAHafsTENPISPISDYFVENAYALAGGQNIVNVILVDFRGLDTLLEVLVLGIVGLAVVVLIKY 799
305675747 715 FIIALGVGIIVTLLGIASS---SQRTKDSISSFFLKHSHDLGGGDNVVNVILVDFRGFDTMFEITVLTIAALGIYSMIKT 791
154687269 715 FIISLGVGVIVTMLGIASS---SEKTKDSISSFFTAYSHKLGGGNNIVNVILVDFRGFDTMFEITVLSIAALGIYGMIRT 791
52787040  715 ALVSVGVGTVVTLLALSAN---SQRSLESIASYFIENSYKLAGGHNIVNVILVDFRGFDTLFEITVLVIAALGIYGMIRL 791
52081655  715 ALVSVGVGTVVTLLALSAN---SQRSLESIASYFIENSYKLAGGHNIVNVILVDFRGFDTLFEITVLVIAALGIYGMIRL 791
157693582 715 LIISVGVGVIVTCLAFAST---SNQSLDTIASYFIENSYKLAGGNNIVNVILVDFRGFDTMFEITVLAIAALGIYGLLKT 791
229918331 717 AIVAVLVGTTVTLLSFMAL---TNKSLTSISEYYKENVYELAAGKNMVNVVLVDFRGFDTLFEIVVLGIAAFGIYTMIKF 793
172057706 717 AAISALVGLSVTLVALASL---SQRSFASIAQYYIDNVADLAAGGNMVNVILVDFRGFDTLFEISVLAIAGLGIYAMINF 793
138896530 711 ALISLGVGALVSVIALLAY---SEKNFASIAQYHIENAYEKAAGKNIVNVILVDFRGFDTLFEICVLAIAALGIYALVKL 787
239828197 716 ALISIGVGVIVSLIALLSY---SQKNFDTIAQYYVENTYEKAAGKNMVNVILVDFRGFDTMFEICVLGIAALGIYVMVKL 792
297584674 800 KASGRDEV 807
305675747 792 KVKEEGKS 799
154687269 792 KVKEEGEE 799
52787040  792 RLEKGGEE 799
52081655  792 RLEKGGEE 799
157693582 792 QGKRKRGV 799
229918331 794 RTTRRTKG 801
172057706 794 RKTGGIDK 801
138896530 788 KAPKGENG 795
239828197 793 RMSKGEK- 799
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