Conserved Protein Domain Family
7TM_GPCR_Srt

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pfam10321: 7TM_GPCR_Srt 
Serpentine type 7TM GPCR chemoreceptor Srt
Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srt is a member of the Srg superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.
Statistics
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PSSM-Id: 402096
Aligned: 37 rows
Threshold Bit Score: 338.037
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
O17701         3 RFIEFGSATSIPLYNCShipltPEqWSEKdGVSRPIFGATEFTFGMLIEILYIPLIVVMLEKKNFsMSCYKIMVFLALID 82  Caenorhabditis ...
Q9N526         3 SLLIYGSVQANPLYNCSak--pASqWTDElGTQRIFLGVILIIFGIIVEILYVPCLGAIYKKKLLqHSCYKIMFLLGITD 80  Caenorhabditis ...
Q19556         3 RIIQYGSVEGIPYYNCSak--tSEeWFAT-GVQRPLFGWSILIFGIVIELLYIPTIYMMFRTKLIhLTCYKIIVCLGVTD 79  Caenorhabditis ...
Q9NAI0         3 RLIRYGNIDSIPYYNCSwr--tSEeWDLQ-GLKRPILGWFLVLFGGFVEILYLPILYIIFKTKLIrYACYKLIVFLTLTD 79  Caenorhabditis ...
Q9U2H5         5 RLLYYGSVEAIPFYNCSw----KSeWFET-GVKRPFLGYSIMIFGVFIEFLYPPIIYLIFKTKLIrHSCYKIIVFLSIID 79  Caenorhabditis ...
XP_002632581   3 RLIHYGSTDAIPFYNCSwk--pESeWWQN-GVQRPWLGYPITTFGIFIELLYIPIVWIIFKTKLIrHTCYKIIVLLAATD 79 
Q9XUC8         3 RLLEYGSVEAIPYYNCShk--nFTeWEKT-GQKRPYFGWPLVVFGVLVELLYIPVIYIIFKTKLIrHPCYKIIVLLALID 79  Caenorhabditis ...
Q9U2H7         3 RLIEYGSVEAIPYYNCSrm--sFPeWEKT-GVKRPWLGYPLIIFGIFIELLYLPIVYIIFKTNLIkHVCYKIIVVLAFVD 79  Caenorhabditis ...
Q966A1         3 SIIIYGSIEKIPLYNCSah--sASeWSELdGEKWPMVGAGLIAYGIVIDLLYLPILLIMLEKELFeKSCFKIMFLLGVTD 80  Caenorhabditis ...
Q22983         3 HILRYGSIDRIPMYNCSar--tPSqWTLEtGEPQPIIGPLQVAYGIIVLTLYIPIALIMLEKENYkLTSFKIMFQLAITD 80  Caenorhabditis ...
O17701        83 FVAVIFSCLMTGFLTFQGAVFCTYPNLIYISGCTAKCTWTGSCLTAMILVINRLLDLSFNRIKNILFDGNRTFLILIIPF 162 Caenorhabditis ...
Q9N526        81 MLTTCTATILSGYLLTVGAVFCTYPELIYVAGCFALGGWVSSCAWTLLLVINRISDMIAPRISDFLFSGNRTWIVALIPI 160 Caenorhabditis ...
Q19556        80 MLATLTCSIFSGWLFIKGAVYCNYPTFIYLAGCLGLSGWCMACGSTLLLVINRVFDVLCRPVSEFLFDGKRVFFSIALIY 159 Caenorhabditis ...
Q9NAI0        80 MSATVCSSIISGVLYIKGSVFCSYPTFEYIAGGFAINTWCMACAINISLFANRVCSIAFHEYIDVI-EGKLTYFCITISA 158 Caenorhabditis ...
Q9U2H5        80 MIATVCSCFISGSLFIQGAVFCSYPSFIYITGTIVLTTWCTSCACTLFLFINRIVNITLPQYSDLI-EAKLAYFSIILSI 158 Caenorhabditis ...
XP_002632581  80 MCAISCSCIITGILLIQGAVFCAYPTFIYICGGIALCTWCGACAITLSLFLNRIVSIGFRDYADVI-EKPMGYISMVLSV 158
Q9XUC8        80 ITATCCSCLITGPMLIMGTVFCMYPTFTYVAGGIAISTWCMACAATTSLFSNRIISIGFRKYADVI-EKKLAYTSISFVL 158 Caenorhabditis ...
Q9U2H7        80 MMATACSCFITGTLLVIGSVFCMYPTFTYVTGGFVLAMWCMACATTVSLFLNRVISLAFHEYADSI-EKRLAYISILFCF 158 Caenorhabditis ...
Q966A1        81 FFTLIIISILTGWFAINGAVYCTYPRIMYISGTIVCALWCSSCMSALLLVANRILGMSKPTWAAMIFDGKKTYIVLMFPV 160 Caenorhabditis ...
Q22983        81 IIGISINSVLTGILAIQGAVFCTYPTFIYLSGLFVMCLWCLTCLTSLILVCNRLLIFFNPNIEAQLFEGRKTFIILGFSL 160 Caenorhabditis ...
O17701       163 GYASYFLIFNPPIVFTSKFHSWFFDPLIfeGRSAE------YNNIPVLFNNFLIVITTCCLYMFFCCALGAKTKNTk--T 234 Caenorhabditis ...
Q9N526       161 PYTLSVMFFTPAIIFNSTVMAWIGDPLIyeERAQD------YYNPIQNLNNVVFISGTIVLYGAYCFFMAKK-------T 227 Caenorhabditis ...
Q19556       160 TYGTLVSMFSPSIIFNSAIMAWIADPLTidPEYKTdeitdwYRNHVQSTNNWIFCSGTCTLYAIYCVLINKM-------Q 232 Caenorhabditis ...
Q9NAI0       159 IYGTFILFYTPIICFNSKALAWIPEPLSeiDDSKEse--kyYNNDWQSWNNYLFVAIMFFLYITYCVLIKKL-------A 229 Caenorhabditis ...
Q9U2H5       159 IYGFYYVFFTPTLCFNSGGMAWFPDPFSekEPSKEaa--eyYKNRSQGWHNWIFVTAMVLLYVIYFLKVRKI-------A 229 Caenorhabditis ...
XP_002632581 159 VYMFYISFFTTPACFNSLIMAWPSDPLSekEPSKEas--ifYRNDSQAWNNWIFITCMLFMFTIYCGLVNKL-------A 229
Q9XUC8       159 FYGFYICWFTPTTAYNSVFMAWIPDPLSeeVPSKEaa--amYKHTILPWNNWIFVACMFILFSVYFIMVKRM-------A 229 Caenorhabditis ...
Q9U2H7       159 SYAFYIFMFTPSIVYNSVFLAWIPDPLSelKPSKEaa--amYKNVPQAWNNWIFVSCMFILFSIYCAMVKKI-------A 229 Caenorhabditis ...
Q966A1       161 LYFIFFM-FNTPVVFSSKYFAWMYTPLIfpDRNLE------YFNRPHTINNFSVVTLTCIVYTPFRIIIANQFKKLihgD 233 Caenorhabditis ...
Q22983       161 VYGGYFL-FTTPHVYNSKHLAWFFDPMIfpGRAHD------YDNFSHAFNNFSIVAITCVLYIPFYEIVRKRLKDAh--S 231 Caenorhabditis ...
O17701       235 SSQTRKMSLQIFFQSAMICAVNFSASMIYVIMNYVEVPFSIILFGQFTWQMGSASPVFIYLTLNKTIRNGVLLKLGlTFA 314 Caenorhabditis ...
Q9N526       228 MGYKVSAGKNVFIQSTLICSINCSSALVYSSMMFHKPNEYIVLFGELAWSFVHGCPAIIYLTMNKTVRQEVLRWIR-RKN 306 Caenorhabditis ...
Q19556       233 RGQKSKASRQVFIQSSIICSFNTFSAMSYNALMFTVPAPWVIAIAELCWSIVHGCPAIIYLTMNKTIRTEFLKFLK---- 308 Caenorhabditis ...
Q9NAI0       230 HGQKSKKSRAIFIQCCIICFFNTATALIYNALSLMTPALWILYLGQLSWSLNHGCPAIIYLTMNDTIRKNFFRTFCrFKN 309 Caenorhabditis ...
Q9U2H5       230 RGQKSKASTAILVQCIIICFFNTTCALIYNSFTLITPDPWVLLLGQYCWCVNHGCPALIYITINDTIRKGFRKLLF--NG 307 Caenorhabditis ...
XP_002632581 230 RGQNSKASRAIFIQCCIICFFNSCTAIFYNVLAFITPSPAILVFGQLCWSINHGCPALIYVTLNDTIRREFKKLIFrSST 309
Q9XUC8       230 KGQKSKASRSIFIQCSIICFFNTGTALVYNALAIVTPAEWILAFGQICWTCNHASPAIIYVSLNSTIRREFLKIVF---- 305 Caenorhabditis ...
Q9U2H7       230 RGQKSKASMAIFFQCAIICFFNTVSAMVYNAVAFITPDFWILLLGQLCWSINHGCPALIYITMNETIKREFKKLVFgIKS 309 Caenorhabditis ...
Q966A1       234 SPQLQNAKTQVFLQSTFICAVNQFGSLIYVIMNVIVVPGWLIMSAHFIWQFVHGCPVLIYLTLNETIRVRFVQKLK-LNV 312 Caenorhabditis ...
Q22983       232 HSRAQNMKLQVFIQSVLICIATQIASIIYVFMNLFKVSTCVILIGHALWQFVQGAPVFIYIGLNEQIRKRFFQLLR-CHG 310 Caenorhabditis ...
O17701       315 FGKTS 319 Caenorhabditis elegans
Q9N526       307 PAVQD 311 Caenorhabditis elegans
Q19556       309 LKKTN 313 Caenorhabditis elegans
Q9NAI0       310 TKIDT 314 Caenorhabditis elegans
Q9U2H5       308 TRVED 312 Caenorhabditis elegans
XP_002632581 310 NKIEE 314
Q9XUC8       306 -RNTL 309 Caenorhabditis elegans
Q9U2H7       310 KKIET 314 Caenorhabditis elegans
Q966A1       313 IFGNK 317 Caenorhabditis elegans
Q22983       311 NGVGS 315 Caenorhabditis elegans
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