Conserved Protein Domain Family
MATE_SpoVB_like

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cd13124: MATE_SpoVB_like 
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins
The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Statistics
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PSSM-Id: 240529
Aligned: 172 rows
Threshold Bit Score: 251.233
Created: 30-May-2012
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q00758        11 LILIAAGMVTRMLGFVNRVVIARFIGEEGVGLYMMAAPTFFLATTLTQFGLPvAISKLVAEAsargdhqKTKNILVMSLT 90  Bacillus subtil...
YP_003238596  11 AVLTFASLVNRLLGFIYQIFLIRILQAEGIGLFSMVFPLYVMTLVLGSVGIPaAVAKLVAEAqaqgnpsRIALIFRLALL 90  Ammonifex degen...
YP_001717373  12 LVLTASSLFNRILGFVYQVLMVRLLKAEGIGLFSMIYPVYVLFLVVASAGIPvAIAKVVAEEsargnlaNAYRIFRISLG 91  Candidatus Desu...
YP_004516800  11 FILLLASLCNRLIGFVYQILMIRLIRPEGVGLFNMVYPIYVLVLVLATAGIPvAIAKLMAEEvargnlgGAYRVFSIAFW 90  Desulfotomaculu...
YP_003190865  11 MVLLAAALINRIIGFIYQIIMIRLIQPEGIGLFNMVYPIYVLVLVVATAGIPlSISKLVAEEtarhnfaGARNIFHVSLF 90  Desulfotomaculu...
YP_430000     11 VILMVASLLNRILSFGYRMLVVRYIGAEGMGLYEMVFPFYSLVLMVTTAGIPvALAKLTAERialarwgQVRSVFRLSLI 90  Moorella thermo...
YP_359807      8 LLMSFVSFLNRILGFVYQVLIVRLLGAEGIGYYNMAYPVFVFLLVLSTLGIPlALSQTIAQEgfk-nrtHSKNLLFFSII 86  Carboxydothermu...
YP_001211946  11 AVLVLASLFNRILGFIYQILLIRLILPEGIGLFNMVYPVYVLVLVMATAGIPvAISKLVAEEmarnnlhGAYRIFKMCFI 90  Pelotomaculum t...
YP_003640678  11 LILALAAGINRLMGFVFQAAVYRLIGPEGIGLFNLVYPVYILILIITTAGIPlAVSKMVAQHlaqnnfrAIKKIFRVALF 90  Thermincola sp. JR
YP_004266356  11 IILFLANLFNRILGFIYQYLIMKYVGSEAYGLYQMVFPLYMTILVFSTAGIPlAVSKMIAEKislgregDAARIFRVAIL 90  Syntrophobotulu...
Q00758        91 ITGVLSLIFTPL-FLFFAPVMAetmltDKRTLYPLLAITPVVPIIAISSVLRGYFQGKQNMNPLAMSQVLEQVVRISLVA 169 Bacillus subtil...
YP_003238596  91 LTAVSSLIVTAT-AFFLAPFLArriltNPQAYLPFVCLLPSVPIVSLCSVFRGLYQGWQNMYPTALSQVIEQVVRVFSGL 169 Ammonifex degen...
YP_001717373  92 FVFGSALVLTVAlLHYGTPLLImv-fdNPDVHLAFKVLTPGILVVSVCSAFRGFFQGLQQMTPTAVTQAVEQSVRVVCGL 170 Candidatus Desu...
YP_004516800  91 WIVASSLFFTLV-LILGAPLLQqyvfpNPKVYYCFLSLVPGIIIVSLCSAFRGFFQGLQQMTPTAVTQVVEQLVRVIAGL 169 Desulfotomaculu...
YP_003190865  91 YLTAFSLLCTAG-IVWAAPLLLkyifpNPKVYYSFLCLVPGIIIVSICSAFRGYFQGLQRMTPTAATQTIEQLVRITIGL 169 Desulfotomaculu...
YP_430000     91 FLTLSGLLAALV-LWRLAPFLTgrmfaDTRVYQAFVVMILALPVVCICSAFRGYFQGWQLMRPVALAQVVEQVVRVSAGF 169 Moorella thermo...
YP_359807     87 FLLLFSLTVLGL-FFSLLPLIRhllfpSEYSFYAFLWLIPSIPVIAVSSALRGYFIGLLRWNIPALAQNIEQIVRILVSL 165 Carboxydothermu...
YP_001211946  91 ILTFNSVFFTVL-CFLIVPLLLeyvfpNPKVFFIFLSLIPGIVIVSLCSAFRGFFQGLQQMAPTAVTQSLEQLVRIIFGL 169 Pelotomaculum t...
YP_003640678  91 LVFFSSIFFTTV-TLVLFPYLVkyifyDPRVSLCFAATIPGIFIVSLSSVFRGYFQGLHDMAPTATAQVIEQVIRITSGL 169 Thermincola sp. JR
YP_004266356  91 LLSFSSVVVTLL-IYINTPVIVakcfpDARVFYVFRICIPAIFIVSVSSAFRGYFQGHQNMVPSAVSQICEQLFRIVVGF 169 Syntrophobotulu...
Q00758       170 VCTTIFLpyGIEYAAAGAMLSSVAGELASLLYLFVCFKYKKtikirkhfl-qsikngkqTFTQLMSVSLPTTGSRFIgNL 248 Bacillus subtil...
YP_003238596 170 VLAFCLAplGVAAASCGASLGVVAGETAGFLFLLFLFRRQLplvgsg------kgslwkEFPPLMSFALPVTFTRLSsTL 243 Ammonifex degen...
YP_001717373 171 VLAYLLMprGIAWATAGASAGVVLGELSGFLLMLLIFFTRRpavgggagvpafteslgvISRRIFSLAGPVTVSRVLsTA 250 Candidatus Desu...
YP_004516800 170 GIAWFMLprGIEYAAMGISLGVVLGEFVGFLSMLAIYFKKRpslspfav--ycsapalkVTGRIFDLAVPVTLTRFVsTA 247 Desulfotomaculu...
YP_003190865 170 AAAYLLLprGLEYAAIGVSLGVVCGELSGFLLMLIIYFQHRpylqhkrq--ktslefaaNSKRIFHLAAPITLTRFVaTG 247 Desulfotomaculu...
YP_430000    170 FLGIYLLpyGVAMAAAGLAAGMVLGELAGLGISVFIFNLARpyydiaad---qtgslkaDILPLVRLAIPVMLARMAgGI 246 Moorella thermo...
YP_359807    166 SLTSAFIniSLKDALRGPSLGVLAGEAVGFLVGVAFLDKKSwfspk---------iplnYLRKIFSLAIPVTLTRVMaTL 236 Carboxydothermu...
YP_001211946 170 FMARLLFpkGIEYAAAGASIGVIAGEVAGLIAMIVIYLKKRpalvssfvl-hpgesfcsILRKIAGMALPVTMARIVsTI 248 Pelotomaculum t...
YP_003640678 170 LLAYYLLprGITLAATGIAASGIIGEFFGFGALIVMYLKRHrgglsgsg---aylrtkyILHEFFNLCAPITAGRFIsTL 246 Thermincola sp. JR
YP_004266356 170 YLAIKFLpyGIEFGAAGLAVGMLVGEFAGLFVIMIHYLISRrkrthrpq---avtryheIIREMFGLSLPVTGSRLVfSG 246 Syntrophobotulu...
Q00758       249 SWFFEPIVVAQSLaiaGVATVAATKQYGELtGFAMTLLTLPSFITYSLSTALVPAISEGMeqkklqVVEYRLEQAMRLCL 328 Bacillus subtil...
YP_003238596 244 FLSLEALLIPHRLvagGYSISEATALYGQFaGVAETLLYTPSIVTVSLATALVPAVAEAAasrdryLLHSRIHNALRLTL 323 Ammonifex degen...
YP_001717373 251 LLSVDAVMIPKRLaaaGLSTAEATASYGKLaGMAQTLLFTPGIFTISLATALLPAISSAHargdtaLLLNRVGSALRLTL 330 Candidatus Desu...
YP_004516800 248 FLSVDAMLIPRRLqvaGMTLNEATGVYGQFvGIAESLLFTPSIVTISLATALVPAISDALaqndlsLVRGRTEEALRLTM 327 Desulfotomaculu...
YP_003190865 248 LMSLEAILIPQQLqaiGLSLKASTSIYGQLaGIAETLLFTPTVITISLATALVPAISDAMaqnnitMVHNRINKSLRITI 327 Desulfotomaculu...
YP_430000    247 MLTIEALLIPRQLqawGVTMREATTIYGQYaGIAFTLIYLPMVITVALAMTMVPAISEARavgdcdLLNKRCRQSLKMTI 326 Moorella thermo...
YP_359807    237 LSALDALLIPKALvlsGLSFREATATYGLFsGVAMTLLLTPAVITNTLSTTLVPGIAEAFgqenfsLIRSRSFYAFKLSL 316 Carboxydothermu...
YP_001211946 249 LLSLDAILIPQRLqagGLGLSEATSVYGQFvGIAESLLFIPGIVTVSMAVALIPSVSEALavkridVVRAHCEKAVRITL 328 Pelotomaculum t...
YP_003640678 247 LVSVDAFVIPRRLaaaGLTSVEATKTFGQFtGVALTLISIPTLLTISLATSLVPAIADAEaknnltLLRSRSDDAIRVTF 326 Thermincola sp. JR
YP_004266356 247 LSALDAVIIPRQLqaaGYSLRKATTLFGELnGTAFTLLAFPSVFTFALATSLVPAISEAVakk-eyRLARSRCSDSIRLT 325 Syntrophobotulu...
Q00758       329 LSGGISVVILFVFADELMRVMYGSSGAAVFIKVMAPFFLLYYFQGPLQAVLQALNlAGAAMmnSLIGALVKTGLIFVLAT 408 Bacillus subtil...
YP_003238596 324 IVGLPSAAILYLLATPLCQKIFGYPEAGVPLRLLALGAPFLYLQQTTTSILQGLGyPFLPFrnLVLASSAKIALLFWLTA 403 Ammonifex degen...
YP_001717373 331 LIGIPSAVIFLTLSRHICGLLFGYPDAGAILQVLALGGPFLYIIQTTTGILQGLGkAVQPLvnLLIASLLKIAGVYYLTA 410 Candidatus Desu...
YP_004516800 328 LAGLPATAVFFLLPKELCQAIFGYADAGVALGTLALGGPFLYLQQTTTGILQGLGrAERPLrnLIIAAAFKVAGIYYLTA 407 Desulfotomaculu...
YP_003190865 328 LTGLPSAAVLAVLANEICGILFGYSETGFILSLLALGGPFLYFTQTTTGILQGLGnATKPFknMVAASLFKIFGIYYFTG 407 Desulfotomaculu...
YP_430000    327 YSSLPFAITFYLFAAPICGLIFATPEAGIPLKILAWGSIFIYLEQTTVGILNGLGsMSTILwtTVAGGIVDLLGIYYLTP 406 Moorella thermo...
YP_359807    317 IAGLPVTAILLLYAAPLTALLFKYPEAGELLVILAVSGPFLYWYQTVTGIFQGLSkPQTPFyiLLGASGVKILSLLLLTP 396 Carboxydothermu...
YP_001211946 329 LTGLPFAAMLLILSEELCGFIFGYPEAGKSLEVLAVGGPFLYVQQTTTGILQGLGeASRPLrnLVLASLFKITGIYFLTG 408 Pelotomaculum t...
YP_003640678 327 LAALPFCLYFYLFAQELTQYIFNAPEVAGLVRILCLGAPFLYIIQTTTGILQGLGkPLVPVknMIISSVLKLAGIWLLTA 406 Thermincola sp. JR
YP_004266356 326 ILIGLPCIVIIYCFADLFAGIFNSSDIAPILKLLSLGGIFTYLHQTTTGILQGLGkTHLPLvhSVIGGMIRIPLMIYLTA 405 Syntrophobotulu...
Q00758       409 rpsLGIMGAALAIVTGMVLVTLLHAATVSKVLPI 442 Bacillus subtilis subsp. subtilis str. SMY
YP_003238596 404 lppLGIKGAALAFAAGYFFMAVLNLFDLLRLSGF 437 Ammonifex degensii KC4
YP_001717373 411 vpgLAMNGVALALVAHLMVMALLNLRDIRRLTGY 444 Candidatus Desulforudis audaxviator MP104C
YP_004516800 408 vpaLGIRGTALSLCAAYMIMSLLNYRDLKKIIAL 441 Desulfotomaculum kuznetsovii DSM 6115
YP_003190865 408 l--WGIRGAAISLSASYLIMAVMNYLDLQYLTGY 439 Desulfotomaculum acetoxidans DSM 771
YP_430000    407 v--LGIAGAALGVNLGTAVTAILNLLALIRQTGF 438 Moorella thermoacetica ATCC 39073
YP_359807    397 k--IGITGTCLSFALYHFLLFILSLFALKLKLRT 428 Carboxydothermus hydrogenoformans Z-2901
YP_001211946 409 lpqFGIRGAAIAIVAGYIITAWLNLADIYRLTGF 442 Pelotomaculum thermopropionicum SI
YP_003640678 407 npnLSIRGTAYSFVLFFVSAASLNIMSLARLSRF 440 Thermincola sp. JR
YP_004266356 406 mphLGLTGTAAAYLIGFFIVAVLNMIAVNHYIKL 439 Syntrophobotulus glycolicus DSM 8271
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