Conserved Protein Domain Family
HEPPP_synt_1

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pfam07307: HEPPP_synt_1 
Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
This family contains subunit 1 of heptaprenyl diphosphate synthase (HEPPP synthase) (EC:2.5.1.30) (approximately 230 residues long) from Bacilli. The enzyme consists of two subunits, both of which are required for catalysis of heptaprenyl diphosphate synthesis. This family corresponds to the regulatory subunit.
Statistics
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PSSM-Id: 399944
Aligned: 14 rows
Threshold Bit Score: 212.931
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8Y5X2                  23 YQYLQENNEGGQMDKDQMLFLHEAISG-SDLTDAAAYRVVSATLYMILAHDTHEKIDEpg-dvVKLTRKEQELTVLAGDF 100 Liste...
WP_014098157            22 HDYLNQFIDAPYIDEDRILLLISSLAG-QPYTEHEVKQFVATAMLIQIALDTHEKVTN-----ANENQKNRQLTVLAGDY 95  Weizm...
PRJNA212797:N288_17050  21 HPYLLKYIDEPVIDQDKLLLLVSMLNE-AELTQKQKNDYSVTAMLIQVALDTHEQVSNtq--iAGEMQKNRQLTVLAGIY 97 
WP_014643521            24 HPFLARFIPEPAVDEDKLVILSSIMDH-TSLSSVKKEQYIITTMLVQIALDTHDLVTLtedddDQETIRNRQLTVLAGDY 102 Halob...
Q8CXF7                  21 YGYIHKHIQQPLIDEAKWGLLQFLVEQdRSLTPMQRERYIITTMLVQIALDTHDLVPIkkvaeTEQETLSKQLQVLSGDY 100 Ocean...
Q5WGT5                  25 YDYLQGYIDNTRPDADELWLVYTILTE--SEPPDRAGAITLAWGFAHAGLLIHDLVSLhn-tnEEFAKKKRQLNVLAGDF 101 Bacil...
Q9KCC5                  21 HAYLEKYITKPIVDEDKLRFLYTMLAE--KLPKKDTKLFTLSALLVDAALEIHEAVSLhn-iqTDPIKKNRQLNVLAGDY 97  Bacil...
Q65I23                  21 HPYLAKHLTAPKVDEDKLFLFYALFEE-TDLKEADKESYILTAMLVQTALDTHDEVTTaa-siKQDDYKNRQLTVLAGDY 98  Bacil...
WP_012010388            21 HPYLAKHLRAPLIDEDKLLLFHAMFDE-AQIDAEKKENYILTAMLVQIALDTHDEVTTaa-aiKQDEFKNRQLTILAGDY 98  Bacil...
Q81SW1                   6 HPYFINYIEEPFIDEEKIALLYGALKG-ANLHIEQIEHYVVTIMLVQIALDTHERVSNksgeeANESHKHRQLTVLAGDY 84  Bacil...
Q8Y5X2                 101 YSALYYRTLAELEMIPLLRALQSGVQETNTAKTNIYQLHVATDEEYLSQLTLTNAAIFAKFAKYFmKDETFIALGCQFFL 180 Liste...
WP_014098157            96 FSSLYYKLLAGVHNVRLVGILAEGIKSVNEYKVMLYQFDDSDAETFVGHLKKTESAIITKFMQFF-GSQPLIRLSEELLL 174 Weizm...
PRJNA212797:N288_17050  98 YSSLYYKILSESKDIGMIRLLSDGIKEVNEHKISVYQHETENVEGLMESVRLIESSLFSKIAECF-NKPAWTELSSHLLL 176
WP_014643521           103 YSGLYYYLLSQLEDIPMIQTLAGAIKEINELKMELYYKDVESFQEFLNGLKKIESLLIQRVASYV-QRTTINDIAGEWLL 181 Halob...
Q8CXF7                 101 YSGLYYFLLSEVGEIEFIQTLANAIREINELKMALYYKDSPTFHERINLTKKINSMLIIHVTQFL-YDDTANDLITDWLI 179 Ocean...
Q5WGT5                 102 YSALYYQALARVHAVDMIELFGSTLQEVYEKKIASHLDKDNSFETRLAQTEEIEALLAVAIANEI-GQEGYEPLLRPFFL 180 Bacil...
Q9KCC5                  98 YSSLYYYLLADSRHLPIIQVFSHSIQEINEYKMKLYDGKNIDFDEVKNNVDKVDTFLLQNLAEHF-QLTTWKKAISVFFH 176 Bacil...
Q65I23                  99 FSGMYYSLLSGMKDIYMIRTLAAAIKEINEHKIRLYDHSAKDADSLKKSVSIVEAALFHHLADHF-YLPHWKTAANDFLV 177 Bacil...
WP_012010388            99 FSGLYYSLLSDMKDIYMIRTLATAIKEINEHKIRLYDRSIQDAAHFYKSVATVESALFQRVSEHF-QLTHWNEIASRFLV 177 Bacil...
Q81SW1                  85 YSGLYYYLLSMNRDIVLIRALAEGIKEINEHKIMLYQKAHKTVDDIMESVVMIESALLQKTCDHF-QLAHWKPFITYVLG 163 Bacil...
Q8Y5X2                 181 LKRLQTELATYKEIGASRLKRAFDHGYFAKEAvSnFESWLVAIIRDVKSEVERLK 235 Listeria monocytogenes
WP_014098157           175 FNRLLREKKQAENGKRSILFEALNKMAYPGDG-RpFEQLPHEKKRKLFYICEKYL 228 Weizmannia coagulans
PRJNA212797:N288_17050 177 MKRLMEERGRYLDQGTSFLFERLKRLVFPKKE-QeLADLSAEQKRYLLLIANRYI 230
WP_014643521           182 AKKLLEEKKSYQEGKFSPLIDVLVKRPGILGN-----------SGQVIVNIEQML 225 Halobacillus halophilus
Q8CXF7                 180 LQQLELEREYNNSVIGETTINAYQKNVSNLAQ----------TLSNQTAFITHYI 224 Oceanobacillus iheyensis
Q5WGT5                 181 YKRLEKEKENAEAGCLSPLIEAWMAENKQGSL---FKVEQQRQLEQLQEAVDKQN 232 Bacillus clausii KSM-K16
Q9KCC5                 177 LKRLVHEREAWINGKATPLMKAIVTELFGSNR-P-VDELKKDDQLQVLELWEEKV 229 Bacillus halodurans
Q65I23                 178 FKRFAAEEKA----SDSRLLETIIQKEFPEGQ-AsCGQLAAAAYKEAKLAINQSL 227 Bacillus licheniformis DSM 13 ...
WP_012010388           178 YKRFMKQAE------DDKHLKLFLNDSHTDAY-TcFDNFENEGYEKARRSIKEHL 225 Bacillus pumilus
Q81SW1                 164 KNRLQKECELHVNKQHSPVFQAVQGIVNDKAD---AETVMNGWMMKLGKKENQFL 215 Bacillus anthracis
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