Conserved Protein Domain Family
PrsW

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COG2339: PrsW 
Membrane proteinase PrsW, cleaves anti-sigma factor RsiW, M82 family [Signal transduction mechanisms]
Statistics
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PSSM-Id: 441909
Aligned: 267 rows
Threshold Bit Score: 86.4951
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
NP_923716    195 L---FNSILALYLAGAGYFFVYRLCG-KSKPWWVLIGAALAT--ALLL-ASPLMAGFfvvFRqwlpgdtdamllraAQGE 267
AFZ22768       1 MadfSLLLWAVIPPLLFLLLYYRRIP-AAPPLSHLLLFFIFGaiSGF--LALRLEewva-------------hwqqIPHs 64 
WP_012409339   1 MvdfSLLLWSAIPPLLLLGYYY-RVP-FAPPLLKLLMFFGIGaiSGL--LALRLEw---nFEtvanwv---vdwerIKRs 70 
WP_015129945   1 MtefSLLLWAAIPPLLLLSYYYYRVF-TAPSLLRLLLLLVLGaiSGF--VALNLEl---gFEtvanwi---vdwqrWQRw 71 
WP_015215490   1 ManlSLILWAVIPPLLFLWFYYRRTH-AAPPPLQLLFFFIFGaiSGF--VALGLEw---tVEnvansv---idwakIQRs 71 
WP_021008666  59 Al--LGILVWGIYTLVFLLVFRTLDLlEQHPPEAFVLAFAWGglGAVY-FAAPANIA---IQslc---------aklVSP 123
WP_023562356  55 Lg--TGVLAFAIYTIPWLVLLAYHNRyTRQPGSLLVAAFVWGaaAATFwIALPANGA---FLsly---------gkaFGQ 120
WP_038676481  61 Fv--VAALLCGLCGAVWAWWFHHIDRwERQPRGLVVAALLWGavPATFgFAMTVNNA---MLsiy---------aklFGQ 126
WP_062249923   1 MvdlSLVPWAVVPPLLLLVYYYWRFA-NSPSLLRLLLFFVAGaiSGF--VALSLEw---lVEtqvnsf---pfwrqTRTt 71 
WP_091803629  57 Vf--VGIVVWVLYGLVFLAFFRSLDLfEQHPPLGFVMAFAWGafAATY-LAISANRS---LLsii---------sklGET 121
NP_923716    268 tvgfveQLVTFFFGAGLLEELVKALPVLAAY--LIGR-RLSQpwrsrlgvlePLDGILLGAACGVGFTLFETFSHYLPat 344
AFZ22768      65 f---lgKALRQLLEVGPIEEGCKLAAVVAPTyhLQRR-YRLR----------ATTVFLFTIAVSLGFTAEENWIYLFH-- 128
WP_012409339  71 l---pgAILRQLVEVGVIEEGCKLAGVVVPTyyLQRT-YRLL----------PSTVFLFTIAVALGFTAEENWIYLFH-- 134
WP_015129945  72 l---pgIALRQLLEIGPIEEGCKLVTVVAASyyYQRN-YRLR----------PSTVFLFTIAVALGFTAQENWIYLFY-- 135
WP_015215490  72 f---fgFSLRQIMVIAPIEEGCKLAAVILPIcyLQRR-YQFR----------ATTVFLFTIAVALGFTAEENWIYWFH-- 135
WP_021008666 124 df---vALWGPAIAGPITEEFLKIAGVILLVl-VARN-QFQT----------YLSVLIVGAMAGLGFQVVENLTYTVNas 188
WP_023562356 121 aw---vNDWGAGLTAPINEEIGKGLGLILLLg-LARK-LVRS----------PFDGLIIGAYIGLGFQISEDVLYAFNnt 185
WP_038676481 127 pw---sADWAAGLTAPFTEEAAKLCGFLLILg-LAPR-LVRT----------ANDGLIIGAFVGLGFAAFENFLYAVNgt 191
WP_062249923  72 l---vgVALRQLLEVGPIEEGCKLIVVVALSwyFQRRqYRLR----------PTTVFLFTIAVALGFTAEENWIYFVH-- 136
WP_091803629 122 gf---aDEWGAALVGPTIEETLKLCGVLLLVl-IARS-QFRT----------IVSVVVVGALVGLGFQLLEDLSYSVKaa 186
NP_923716    345 veqftvqtgalgiGe---ATGLQLLIPR-IIGNVSGHMAYSGYLGYFIGLGALKrtP--A---RRWWIFLIGYLSAASIH 415
AFZ22768     129 -------------G-------TASAVER-SIGTPV-HAMFSAPWGYAWGIYISS--S--MrlnRDRNLIFRAGLNSVICH 182
WP_012409339 135 -------------N-------TGSILGR-TISTPV-HAMFSAPWGYALGMYISS--K--NrlyQDRKFILWAWLNSVICH 188
WP_015129945 136 -------------N-------TASILDR-SIGTPV-HAMFSAPWGYALGMYICS--H--TrrhQYRHLLPGAWLNSVICH 189
WP_015215490 136 -------------G-------TASILER-LISTPV-HSMFSAPWGYALGIYIAS--T--RrlnRDRNLIFIAWLNAVFFH 189
WP_021008666 189 mhfp---------lenqvSPVLINLLTRgLLSGLWSHAAYTTIASFGVAWFLLH--PerSm-aARIACAFLCFALAWAMH 256
WP_023562356 186 a---------mnfGadqvGSAWQIVLIR-SASGLFGHVLFSAVFCSGVMWLLGR--G--Er-tHRL-RGLLLMLAAMVAH 249
WP_038676481 192 a---------gafGtdpvGNAVQVSFTR-IGVSFVSHPLFSALVCSGAIYLLGT--A--Aq-pRRVGRGIALVVAGMFLH 256
WP_062249923 137 -------------N-------TASILER-SLSTPV-HAMFSAPWGYALALSLPR----------YHPRVAKAWFNSVICH 184
WP_091803629 187 vqfp---------tndqiAPVIQIFFVRgILSGLWSHALYTSIAAFGIGYFITR--TyrPf-aARLAVAVASFALAWFVH 254
NP_923716    416 ALWNAAGV-------L---Ge------------------------pV----------------LAIAGVLa------fAF 439
AFZ22768     183 ALANILSSawgypppLrflSsglfpflvwmfwrleqllrrvqgkrpIplisgytlqrrywqrgLVLFTLIlsgnalfgLF 262
WP_012409339 189 ALVNILSSacsyslaLcflNyglfpfllwmfwrleqllrkvqgkpvItliwertpqrrywqrgLVLFALVlggnaifgLF 268
WP_015129945 190 ALVNVLSSawryptpLnfcSyglfpfllwmfwrmeqllqrvqgkfpVvlisgitpqqrywergLLLFALMlggnaifgLF 269
WP_015215490 190 ALVNILSRawvyplpIhflAyalfplllwmfwrleqllrkvqrkppItlisgytpqtrywqrsLVLLILLlggnaifgLF 269
WP_021008666 257 FIWNSPWL-------E---Dlfdggyg-------------dmavllV----------------VKGIPAM--------IA 289
WP_023562356 250 GAWDDMSA-------L---Gy------------------------lL----------------AGTVGVL--------LL 271
WP_038676481 257 FTWDDASG-------L---Gng---------------------------------------ngLQVIAVMaa-----sII 282
WP_062249923 185 ALVNVLSSawrypqpLsflSyglfpfllwmfwrleqllrkvqrippItlisgytpqhrfwqrgLVMFALIlggnaifgLF 264
WP_091803629 255 FFWNSPWL-------T---Dlfgdnpl-------------galaqiV----------------IRGIPIL--------II 287
NP_923716    440 LMA------------------AILKarkl----------------sptRPRET 458
AFZ22768     263 ILIrkllplrpvqllypdismFILRqlllnlsfgvlawiiyrylrhsaRRRYF 315
WP_012409339 269 LLAnkisflspsklfdsyilwFIFSrfllnlffgvlawgiyrylrhsaRRRYF 321
WP_015129945 270 LLArklsplslsqlfypdvlrFILSrfflnlvfavvgwliyrylrrsaQRKFF 322
WP_015215490 270 LLArklsplrleqlfepdifsFILKqiainlslgvlswliyrylrylaGRRYF 322
WP_021008666 290 AGL------------------FWRVaa--------------------rENGAY 304
WP_023562356 272 wfvvmpiadllllwlafrlaapqeqgwlrdilapetetgllteaevtaaaggw 324
WP_038676481 283 LAMv-----------------LLRWafra----------------aapREHQL 302
WP_062249923 265 LLLrnlssvtpaqlfeptilwFIFSrlllnftfgliawkiyrylrnqvRSKRF 317
WP_091803629 288 GSA------------------IWWLag--------------------rDESTH 302
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