Conserved Protein Domain Family
Somatostatin

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pfam03002: Somatostatin 
Somatostatin/Cortistatin family
Members of this family are hormones. Somatostatin inhibits the release of somatotropin. Cortistatin is a peptide that is related to the Somatostatins that is found to depresses neuronal electrical activity but, unlike somatostatin, induces low-frequency waves in the cerebral cortex and antagonizes the effects of acetylcholine on hippocampal and cortical measures of excitability.
Statistics
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PSSM-Id: 367290
Aligned: 5 rows
Threshold Bit Score: 27.8594
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9DDE4        90 EERKTGCKNYFWKSRTAC 107 zebrafish
2_pfamImport   1 HQDKTPCKNFFWKTFSSC 18 
1_pfamImport   1 RERKAGCKNFFWKTFTSC 18 
XP_004084506 102 RNRKDGCKNFYWKGFTSC 119
XP_006638042  99 RERKAGCRNYYWKTITSC 116
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