Conserved Protein Domain Family
Mycoplas_LppA

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TIGR03490: Mycoplas_LppA 
mycoides cluster lipoprotein, LppA/P72 family
Members of this protein family occur in Mycoplasma mycoides, Mycoplasma hyopneumoniae, and related Mycoplasmas in small paralogous families that may also include truncated forms and/or pseudogenes. Members are predicted lipoproteins with a conserved signal peptidase II processing and lipid attachment site. Note that the name for certain characterized members, p72, reflects an anomalous apparent molecular weight, given a theoretical MW of about 61 kDa.
Statistics
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PSSM-Id: 274602
Aligned: 7 rows
Threshold Bit Score: 361.454
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P55802           2 KKATKLLLSILPISSISFLSVVSCSTRNSNAK-----Q-----PDKKPE-KPNEKGPIIPKNPDNKKPTNNnnn--snNN 68  Mycoplasma my...
P55801           2 KKATKLLLSILPISSISFLSVVSCSTRNSNAK-----Q-----PDKKPE-KPNENTPKTPSKPDESKQPDN-------NN 63  Mycoplasma my...
AAF06069         2 KKATKLLLSVLPISSISFLSVVSCTTTSSNSK-----Q-----PEKKPE-KPNENTPMIPRKPDDN---DNnsn-dsnNN 66  Mycoplasma my...
CAL58865         2 KRSKKILLTTAFVPLLSTALAAKCEDKENNS------S-----NKKPPAaKPSD--PVLPKKPG---------------- 52  Mycoplasma ag...
LNCCBR:MHP0661   3 SKKTKKYIFLLLNPLALLFLSASCSNTAPATTkiskdQ-----KEDKGTiRKEVENPKKSEEKPSTEKSEVstk-kseSS 76  Mycoplasma hy...
WP_011166438     2 RKFNKLFLTILPISSISAFSVVSCTTNTKNNN-----QiptipNNKKPDnRPSENKPGSTEEHTNKEPNENtnnqkqpNS 76  Mycoplasma my...
WP_011386937     2 krttklllsilpissisllslvscsTTSSNNK-----K-----PEENRTdKTPEKLPENSKKPE--------------NA 57  Mycoplasma ca...
P55802          69 SNSNNNKPGSTVPNENKDPSKSEETPEKPERDPKKPD-KQPQ-GDDPnnhqphnnqHADQPNINKDEFADLDKLPKEISF 146 Mycoplasma my...
P55801          64 TNPGDSNNGSNNPEIKPDPSENPQSDQPMDKPDEKID-KPSH-SDKP---------QADDSNNNRDIFSDLDKISKEISF 132 Mycoplasma my...
AAF06069        67 FNPDHKKPDSTNPSENKDPSEPEE---------KQPD-IKPQ-GDDTnnn---lqpHNDQPEINNVDFSDLDKIKKELSF 132 Mycoplasma my...
CAL58865        53 -------------ESQPEPS--------------KPD---------------------DTTNNNDVNFSDIESLSKSLKI 84  Mycoplasma ag...
LNCCBR:MHP0661  77 EEKIEENPKNKPVEKKDEIGKQKDEISKPKDENPQTElDKPQ-AEEDhqvekidvkPFNPKEDQKDDDIKLARLKGYLST 155 Mycoplasma hy...
WP_011166438    77 SEKSEAEPSPGKPENKPDNSHNQKQPEHNNSNPNNTD-NNNSnADQPqg------dHPQEEPLNKVDFSDVNKLDKEVKF 149 Mycoplasma my...
WP_011386937    58 EPNDQHEPSKSDSEKKPDASDNKNNIK-----PKKPDsEREN-TDQP---------QADQPNHHNVDFSDLEKIKTKLSY 122 Mycoplasma ca...
P55802         147 ERFDFYTSKD-----ATTALSHLRTDGSVI-KIIFSNTHRNIFG-KYNINLEL-DGNEKEDVKKGLIDKVKVKFTnkKDK 218 Mycoplasma my...
P55801         133 ETFSFYTQRD-----AVTALVDLQKDPSTI-YTIFSKDYKTIFD-KYHIQFLA-NNEESANNEKGLIEKVKLKFThkKFD 204 Mycoplasma my...
AAF06069       133 DNYLIYKQKD-----PISAWSMLKNDLSTI-TTVFYNTNKNVKR-EYKLSLESpNKDPDFISKKGIIDKVKIKFT--KEN 203 Mycoplasma my...
CAL58865        85 TNYS-YSKLD-----PKTALSEILKDESIFfKDVF---GEKVLE-LYNLKIS--SESVKYDFDEGLLINLAISFT--KKN 150 Mycoplasma ag...
LNCCBR:MHP0661 156 LPNTLYVTTSlqndlPLTIIHSGKGEKKDFgYVNFVKPIQDFNDtEYEAKLDFsDAQQKENKTKNPIENVGLVLSlkDNK 235 Mycoplasma hy...
WP_011166438   150 EFFTTYSRMD-----AKSAWVQIQGRQPAIfKEIIFKGKNEILN-RYEIEFDS-QKVPNIVDEKGTIDNVGIKFS--KNG 220 Mycoplasma my...
WP_011386937   123 KSIKLYSDKD-----PRSAWFSLKNDLETF-SNIFYRENKDLKN-KYNLSFE--NNEPIYDFLKGVIDNVKVKFT--NNK 191 Mycoplasma ca...
P55802         219 K---SKIIEFTFTGFKvIQKSPDKENKnsKKNYIKKKEKIdNKLTGLYPSLVAYMIMYTQEP---KNYKNLMQ--KDSIN 290 Mycoplasma my...
P55801         205 Q---SKILDFIFTGFK-KNEYTSITNN--KEKYITKREKV-EKITDLFPSLIGYVLLYSQDH---NQYKNLMEa-KNVIN 273 Mycoplasma my...
AAF06069       204 N---FRILEFSFIGFKvTEIDK-NKNK--KYDYIKPKETVdSRLSGLYPSILAYMLLYAENT---NNYKSLQEtdKDAIN 274 Mycoplasma my...
CAL58865       151 V---TKTFDFTIAGFKkKEQNSNSSNK--KENYISAKEPd-EKIKGLFPSLIARMLLYVDNP---ERYKDITS--NNKVN 219 Mycoplasma ag...
LNCCBR:MHP0661 236 KitsSKKIRLLYT----------EEQE--NKSHLKAK-SLpESFKHIFPSFLAFALLNKE---------------KEVIS 287 Mycoplasma hy...
WP_011166438   221 K---SKTREFVFTGFKkLENKIDKGKN--KDEYIKPKTNIdKSLSGIFPSLVAYMLLYSEETqsnNKYDRNIKqsGNVIN 295 Mycoplasma my...
WP_011386937   192 H---SKIISFTLTDFKkTNTTTNNK-----ENYIKEKDELdNKFKGLYPSLVAFMLLYSEDP---QSYKSLEQr-TQAIG 259 Mycoplasma ca...
P55802         291 FEELENNNPNLFADPEINLNVVAlKDLLLEYNRELGKLYKDK----VIAVSYDDVNGKLGLKLLIENREENDTiASKYSE 366 Mycoplasma my...
P55801         274 FEDLENGNSSLFIDKAPLLNVATiKDYLFEFNPELGKLYKEK----ITAVKYDDYNGILGVKLEIENRDFDPKtTKEPII 349 Mycoplasma my...
AAF06069       275 FEGLINKPTNLFNDKFVGFSVGT-KELLFDFNENYRKLYVYK----LVGAGFDDINGTLTLKVEINNSEENKE--KEPGI 347 Mycoplasma my...
CAL58865       220 YEALLNANGKYFSTNTTPFGPGT-KEAFFTYNENLREEYIDK----IVAAGYDDSAGTLQLEVEIKNNPEKNS--NEPSI 292 Mycoplasma ag...
LNCCBR:MHP0661 288 LP-FFNESGYVLNNQ--NFGAGL-KSIFAEFNNSENNSQKNKfgfdVVSAQPDDEKGELKLNFQLWKINETNGdQKEI-- 361 Mycoplasma hy...
WP_011166438   296 FDELRNKNLELFGEDFVGFGVGT-KELLFDYKDEYNKIYKDK----IVAARYDDINGILELEAQVSNTDEYEN-RNDPTK 369 Mycoplasma my...
WP_011386937   260 FEDLYYSNRNLFNNEYPGINQVT-KKLLLEYNYDLSKIYKDR----IIQAKFDDTKGTLGVKIEISNNQTEPKiTKEPTL 334 Mycoplasma ca...
P55802         367 TLEFDFVGFRKIDLKNPNKNVLSLLFPQNNFK--DMIKNNVFKKKIEVLkSGKQKEd----MVLVKEEYAKQLIFKNLLV 440 Mycoplasma my...
P55801         350 EKEFVFDNFRKVNIKDNEKNPLSLFLTQDKFK--EMTKSGLLKTKIQELrSSNKLEkk-elLQDKKIDFLKQQIFKNLLV 426 Mycoplasma my...
AAF06069       348 SKEFSFKGFRKVNTDEPSKNPFYVSLTPADLK--KIITDKSIKKNLEDLhLDITKEnnlldFGIDSRGIWGDQILKHLTI 425 Mycoplasma my...
CAL58865       293 TKTFSFAGLKKADLQNPTNNVIGFSLTPMSFKnlQIVKSILSKRTKESIkAGENILk---dVDENQQKFLKQKIVSELNV 369 Mycoplasma ag...
LNCCBR:MHP0661 362 -----FPKIESLTFSNLAKN------SDNNYE--IQLDEATTNTNLNNEdFGLKNAgenlnTSKFKKNEFIKKIIDNIRV 428 Mycoplasma hy...
WP_011166438   370 NYKFTFKGFRSIDFNNTNKNVLSISLQQRFLK--KLVDNKILKTIIDQL-VQHNHFnhkapVSNINNSNLKGELFEKLTV 446 Mycoplasma my...
WP_011386937   335 IKEFNIKGFRSIDFKDENKNVLSMTLLQSNLK--EMIKKGSLKKTVELLrERNNSFgvkmpLEQVEGTRLKDELFKYLLV 412 Mycoplasma ca...
P55802         441 QI-IDNENNLYRSTQTLSLQNn-kKDNYTSILGLAGGGTLYPFHTIINNNSIKNI-YLMINKEKNKKyKVAINFEVDIPI 517 Mycoplasma my...
P55801         427 DI-NDNSHNIYRSQSTLSLGS---NKTYKSILGLAGGFSIYPFHTSINKDSIKNI-YLSINKDEENVhKAIIEFEVYIPV 501 Mycoplasma my...
AAF06069       426 SL-TDNDNHIYDSKETLTFRKs-kNNDYKFILGLKHNMSLYPFNTMINNDSIKNI-LLSVKDK-----KITLDFELEIPV 497 Mycoplasma my...
CAL58865       370 YI-SD-SNKAYQDGFSQSAKV-------LDLPSLGNSFVLYPFFTWIGTESIFDL-KLELVTGDTGKlK--LSFNIKLPV 437 Mycoplasma ag...
LNCCBR:MHP0661 429 NIkAENINNKWLKVSEAKYKN----------------WLIFPQIQYANLDSTKLInNLKLEKQQENKiSWTLKLESYLLD 492 Mycoplasma hy...
WP_011166438   447 DI-IDDENYLYKSSQTLKIGLfkkENNNKSILGLKNQMSLYPFHSRITKDSIKNI-YVTINNKSAIK-ELELEAEIQIPI 523 Mycoplasma my...
WP_011386937   413 NV-DDNSYHIYNPKQTLSLQKn-sKNDNTSILGLAGNMSIYPFHTRITKESINKI-FITLAKEDDGKlKVTIDFEVIIPI 489 Mycoplasma ca...
P55802         518 FASTTSDLTFHaTSGDTNILKLDITTNALI 547 Mycoplasma mycoides subsp. mycoides SC str. PG1
P55801         502 FSTGFSDLKSYaTSGDEKYLVLKIVQTTSI 531 Mycoplasma mycoides subsp. mycoides SC str. PG1
AAF06069       498 FATGLSDLTSF-SSYNTKTLKLKISSTTSI 526 Mycoplasma mycoides subsp. capri LC
CAL58865       438 FAQGIGDLKDY-SNSNNKQILIPVFTEANI 466 Mycoplasma agalactiae PG2
LNCCBR:MHP0661 493 NNQILTPDSDF-VFGKQKTITIK--GEMQL 519 Mycoplasma hyopneumoniae 7448
WP_011166438   524 YSSILTDLTDH-TYAEEKPLKITVNQKIKL 552 Mycoplasma mycoides
WP_011386937   490 YSVGYSDLKSP-GTGASIPLTLKVNSSALI 518 Mycoplasma capricolum
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