Conserved Protein Domain Family
Tm-1N

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COG5441: Tm-1N 
ATP-binding helicase-inhibiting domain, Tm-1/UPF0261 family [Defense mechanisms]
Statistics
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PSSM-Id: 444192
Aligned: 123 rows
Threshold Bit Score: 425.732
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_106789263   4 KPKIIVAGMCDTKYTELKFLAEQVEKAGGDVKVMNCGCGKV----CdWPDISLQDVLDADGIKQEEVF---KVPRSTAIK 76 
WP_004513094   9 GSKVLLIAAMDTKGTEARYIESWLAKAGFTTLIMDMGIRGKr---PgPVAVTRDEVLRAAGKTWDDIQn--VTSEGDAVD 83 
WP_011365918   4 KKGIVIICNLDTRGEDIIFVKQLIETRGHNAYFLDFSMEEPp---PfAGDITCEHVAERGGMTIEAVRecyRSDRDRAME 80 
WP_011236026   4 KPKVLLVATRDTKNEESQYIRQCLEDAGVEVYHLDASIRSTl---DgDVAIGPDKIAGAAGMTMPEIRa--LRHEGLCLE 78 
WP_006523060   2 EKTVVIVSTLDTKAQETKYLKGQIEKKGYKALIMDIGTKDSp---NiSADITREEVLAASGKEIDTEKl--SQNRPQLMQ 76 
WP_014271006   1 MTIIAVIASFDTKYHEVAYVQQQIEELGCTPFLIDISTGPNppliAiTADIPRDDVLRMGGSSWETIk---KLDKGNAIK 77 
WP_014808713   2 ERIVLLISTLDTKCEETMFLRDKIRDLGAYPLVMDLSMSRDv----pGADISPAQIAEAAGTNIEEIRa--SSERKKITN 75 
WP_014808715   2 QPTVAIVATLDTKGEEVAYLRELIQADGCNTIVIDVGTLHPp---TaTPDISRSQVVEAAGYGVDILNr--QKNRRASVQ 76 
WP_014957106   4 SKTVLIISTLDTKREETRYLKYKFKEISVLPLLMDLSMRGKe---KsHAELTPSDVASAGGSTIEQINn--SKERSTITN 78 
WP_114563125   5 NPTILLIGTADTKMDELRFIQHCIDGLYGKHILMDVGVLEG----AtGVDISNNQVAAAAGVDIPSIIa--YHDENAAMS 78 
WP_106789263  77 MVGEAGAKKIMQMyeaGEVDGIISWAGSMGTTTVTYLMRALPFGVPKIMMTDMAS--S--DV-SMWLGNKDIYIMNPTAE 151
WP_004513094  84 IMISGGVKCALALykaDLIQGVISLGGTMGTTLGTGVMRAFPIGFPKVMISTIAA--K--DT-EAFIGNMDIFMLNSVSD 158
WP_011365918  81 NQIRGASAIVADMmkeGKIQGVFGVGGGTSSLVGTSVMKGVPFGIPKLMASPMAAhpS--YV-GKYVGTHDITMHHTVLD 157
WP_011236026  79 VMIRGALKCADELnrnVGLSGILGLGGSMGTVLATRIMQTFPYGLPKVMISTMAS--G--MT-GPFVGAKDIMMVNPVCD 153
WP_006523060  77 LMVEGAGNKSKELyalKKLHGIIGIGGATGTIMGTGVMKALPFGVPKLMVSSVAAarG--LT-SRYFGTADIAIMHSVID 153
WP_014271006  78 SMSDCVSKVIYTLhseRKIDGVLGMGGLQNTIICSAALRQLPLGFPKFICSTIAS--GnrYF-DTVVGDKDITVMPSIVD 154
WP_014808713  76 QMIAGAVKTAMHLfgeNRLGGVIGLGGSTSSLMATEVMRAMPFGVPKLMVSSTAAlpG--LS-THYIGTGDISIFHTVIE 152
WP_014808715  77 AVIEGASAVVAKLydqSRFEAVMSVGGGTGTHIGMSVMRCLPLGVPKLMVSTVAS--R--DM-SQLVGTKDIAVMHSVID 151
WP_014957106  79 IIIDGATKIAKDLyaaGKIHGVMALGGSTGSLMATDVMRALPFGIPKLMISSTAAlpG--LS-TKYIGTGDILLFHSVIE 155
WP_114563125  79 AMALGASRLAAELyaqGSIDGLLVLGGTMGTDLALDVASALPLGIPKVVLSTVSY--S--PLiPTDRIPPDLTMILWAGG 154
WP_106789263 152 -QGVNTVTRKMVANAAAAIVAMAQVGE-Ih------DTEEKPLMAITAYGTTT-QTVNACSAYWNAKgWDTIIIHQVGTG 222
WP_004513094 159 lAGLNRITRKVLRNGALAIAGLVRERE-Fh------DEFSRPLAVLTTLGTTE-ATAARMRIHFEAWgYESVTFHTTGTG 230
WP_011365918 158 vVKMNPLLKAQITNAVGAICGMVEMTQgTn------ITFDKPCVAISSFGFGE-MAVQTALGMLDEAgFTPIVCHAQGKG 230
WP_011236026 154 iSGLNSITRNAFRSGALAVAAMAHDYQ-Sg-----eAGGNKPLITVSTLGTTE-KCSARVRRSLEQQgFEVMVFHTLGTG 226
WP_006523060 154 fTSLNDLMRDVLDRAAGSILGMVEMKE-AdaavgagRKQGKMLVAMTLLNMCE-KCATHVRRRLEQEgYQVIGFSATGVA 231
WP_014271006 155 fAGINPISEVVLANSVASVVGMVKYGK-He-----iDTHGKHYIGATLMGITN-DTVMRAINNLTVKgENVISFHSTGIG 227
WP_014808713 153 iSGLSKPLCNVLERAAGAIVGMASAEP-Ltve--saRSEGRPLIALSMFGPTE-HCANHIQNRLQREgYQVIGFSAAGVC 228
WP_014808715 152 iLGLNPISKRILKSAAAAIVGMASKAG-P-------IASEKPIIGLTSFGFIT-EGATSVKKLLEDTgYEVAPFHANGTG 222
WP_014957106 156 iSGVTDMLANVMDRACYAMKGMIKYVN-Ns-----fAGSDKKTIAMTMLGPCE-QCASSVRQALEKEgYQVTGFSAAGVG 228
WP_114563125 155 lYGLNSLCKATLSQAAGAVVGAAQAAL-I-------PTFDKPIIGMTSLGKTClKYMVKLKPALEQRgFEVAVFHTTGMG 226
WP_106789263 223 A-TMEDLI-RSGMITAIIDLTTGELTNNMYDSIygtpSTW-NGERVTAASDMGIPQIVTPGGCDQS--AYNPISSMKQEY 297
WP_004513094 231 GqAMERMV-NFEPVSAVVDLSLHELIDHHFGGA----FDP-GPERGRAALQKGIPTVIVPGNIDFL--VTGPMAQAQIYF 302
WP_011365918 231 DkAMEDMI-RAGAFHGVLDICTGGIVENLFKGN----RDP-GPDRFMAAVETGIPMVLAPCGLDIL--SYGGRPDMLEKT 302
WP_011236026 227 GaAMEQII-RERDVAVVIDMSLIEVSEYLHGGL----CAT-GPDRGKAALEKGVPTIFAPGNLDFL--VAGPLAEAKVRF 298
WP_006523060 232 DmAMEELIgKEGIFNAVIDLAPGAVGEELIGGT----RAA-GPHRLEAAGKAGIPQIIAPCLVNLM--TPPKSKYKPD-Y 303
WP_014271006 228 GrVLDSQI-RDGNIAAVMDLCLHEMTAEYFGGLg--ySKG-ANNRLLAAAEMGIPSLICPGGIDFA--CLSKEDFFDDED 301
WP_014808713 229 DrAMEQMI-GLEFFDGVVDLTPGGVGEEILGGM----RAA-GPERLTSAGKLGIPQVVAPGGVNLM--SPRKSRYKPE-Y 299
WP_014808715 223 GmAMEDLI-DQGLIDGVLDFALHEFSDALYNGY----CGGiGPGRLESAGKRGIPQVVVPGGLDCIvlEFDSIETMPSDM 297
WP_014957106 229 DrAMEKMI-AEGFFQGVIDLAPGGVGEHYFGYM----RDG-GPDRLESAGNKGIPQIISFCSVNHM---TPSRSKYKKEF 299
WP_114563125 227 GrAFEGLA-AQGVFSAVMDFSLQELSNLLGGSA----VHA-GETRLLGAGLSGTPQIVAPGAIDMI--DMPTWAPVPDAL 298
WP_106789263 298 lddykAGRRrtwkdtglPYIHNEGVTIMYPTMDEIVELSEYYAEKLNTTKGPTAFILPMQGWSAYDQRKeiattergwsa 377
WP_004513094 303 -----PGRR--------GHKHNANITCVRTSLEEIQRIAEIMAGYCNESTGPVAVLVPMKGFSCLDHED----------- 358
WP_011365918 303 -----KDRP--------QYVQDSLRVQVRTTADELRQAADVIAERLNRANGEWTFLIPLKGWSSQDLEG----------- 358
WP_011236026 299 -----PGRR--------YHEHNPALTAVRAEAQEFRNDAEHLAGLIRTARGPVSFFVPLQGFSNHDSPD----------- 354
WP_006523060 304 -----YSRK--------RYDLDALRTFLRLSPDELVMVAETFAGKLNQARGPVKIIIPTRGWSGIDGEG----------- 359
WP_014271006 302 -----KRGF--------VWHSKDYLTHTRLWESEILDITRTIIQRVNCAKGITEIVLPLGGLRTMSRPG----------- 357
WP_014808713 300 -----HQRR--------KYDLDALRTFIRLSDDEMKQVSEVFVEKLADAAGSTVLMFPTQGWSAVDRPS----------- 355
WP_014808715 298 -----KGRS--------VFWYDFR-SGVRTDRCDVIRLAQIIGEKLNRSNGPVRFIVPRLGWSEADCQG----------- 352
WP_014957106 300 -----HERR--------KYDLDKFRTWLRLSPDELKEVACEFARKLNGAKAPVKLLIPTRGWSSVDCKG----------- 355
WP_114563125 299 -----KEVD--------IRTHNRLISCAASPEPMRRLVAREIVARMSQSTAPSCFILPKQGVQAWDKAG----------- 354
WP_106789263 378 engdGPQWDPDPENPtwsirstvMRKILEEKFDpd----nENLDLIIADMHIVDQEFADLCNEVMEAMLNG 444
WP_004513094 359 ----GPQPDPEGPRV--------FAETFARALT-------RTIHFETVPLHINDEAFSEVIVGALQKIGGL 410
WP_011365918 359 ----RIIYDPAADAA--------FVARLKEKLD-------EPERVKEVDLHLYTKEFARVAVDEFVRLYEG 410
WP_011236026 355 ----GHLHDPSLPPV--------FLAHLKTVMP-------AGVPVVELPLHINDEKFADALVEQAVAFSKY 406
WP_006523060 360 ----SVLYDPETDRI--------FVEELRKRLR-------PDIEIREVEANLEEPVFAEKVLEAFKDVMKA 411
WP_014271006 358 ----EFFFKPDTIKK--------MKVIFDEELK-------PEIVCKAFDLNFDDPDFADICANEMLALLEK 409
WP_014808713 356 ----SHMFDADQDRI--------FLNVLREKLG-------ARLDIREVDANLEDDRFAEAVEEVCLEVFPT 407
WP_014808715 353 ----GPLFDPETNSA--------FLAELKSILD-------SRIPVIEVEAHINSKEFAAVAVSHLHELMKS 404
WP_014957106 356 ----NPTYDPEEDKI--------FVETLKDGLNfgkagldSGIEIIEVDANMEDSAFSQQVTMAALELF-- 412
WP_114563125 355 ----EELCDESGKAA--------FNDELIASAA-------GKIDVIELDAHINDDAFVDAVLAVFDDWLAR 406
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