Conserved Protein Domain Family
DUF4185

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pfam13810: DUF4185 
Domain of unknown function (DUF4185)
Statistics
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PSSM-Id: 433495
Aligned: 54 rows
Threshold Bit Score: 209.077
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AHC27412      360 FAPNDTFNRYGIWGTDIGTMWD---NGipddpntpinenQVLIAFGDTFG------GPNmtgtWRLNTLFRSPDRNLA-- 428
WP_011731164   43 agtgTPTGDYGIGATDLCEFMEfp--------------sRVLQVCGDSFAgqavgfGg-----WYSPIALHVESDSIDdp 103 Mycolicibacter...
AHC27720        8 agtgTATGDYGIGATDLCEFMEfp--------------sRLLQVCGDSFAgqgvgyGg-----WYSPVALHVDPDSI--- 65 
WP_013806046   12 tGPGTSSAKFGVVGTDLGIPAVlpdHE------------TIGWVFGDTFEgtgpgtRg-----WRSPVLLRSQRAHPS-- 72  Hoyosella subf...
jgi:Snas_2970  57 TGPGITT-RFRMEATDLGIPATt-pDG------------RTLFVFGDTFEnaqvggGw-----WRSPVALWSETGDLN-- 115
jgi:Kfla_3477  51 TGPGLTD-RFRMAATDLGIPARt-pDG------------RMLFMFGDTFEqpyvggGw-----WRSPVALWSTTTDLA-- 109
WP_013020724   50 ltGNDNTIKFGVNGTDLGIPVVt-pQG------------KNLYIFGDSYEgpkptpEDAn---WRSPIGLFSGTTDLP-- 111 Stackebrandtia...
jgi:Gbro_0806  22 TGPQCSD-RFGVGAADLGAMTDl-pGG------------EIISVFGDTYRdaragsPd-----WRSPVILIGHRDDA--- 79 
WP_013827017   16 TGPGITD-QWGVTCADLGASVLa-pDG------------SLVSVFGDTFAgdkvgrGd-----WRSPVILIG-TGDAG-- 73  Mycolicibacter...
CAM02135       11 TGPGRTD-HFGIGGTDLGVMAVa-pDG------------RLVSVFGDTFEragvggRg-----WRSPVVLFGDPATAR-- 69 
AHC27412      429 DGLavpggqwfngnMFGGSPLw---------EEHYARQIILPErl------pK--GLPTGVTLIPTAGISVptpgtkyGA 491
WP_011731164  104 AGI-----------RYNGVSGvdkplladptPPGSSQ--------------------------LPAGVVSI-------NR 139 Mycolicibacter...
AHC27720       66 TGVl----------RVTGVSGvdtplladptPPGASQ--------------------------LPAGVVAI-------NR 102
WP_013806046   73 AGV-----------TFNSAAG-----------GDYAKRLIPESntn-------------gvTWLPADVLTL-------DG 110 Hoyosella subf...
jgi:Snas_2970 116 GGV-----------TWSGAVG-----------GDAAQQLWAYDhd-----------nPQFSTVLPSDVITI-------GD 155
jgi:Kfla_3477 110 GGV-----------RWSGAVG-----------GAAAQQLWDYPhd-----------nPTFSTVLPSDVITI-------GG 149
WP_013020724  112 SGL-----------VFDGAIG-----------GEVARQLWDYQhn-----------nGEFSTVLPSDIITI-------GD 151 Stackebrandtia...
jgi:Gbro_0806  80 GQL-----------VWDRAGGp---------DPEYARQLWPYVhd------sPpwRSGGFSTVIPSDILRV-------GD 126
WP_013827017   74 HRI-----------RYRRAGGp---------DGDYARQLWHYRhrepvsrldR----SSISTVIPSDLLRV-------DQ 122 Mycolicibacter...
CAM02135       70 TGV-----------EWTGSTG----------AGAYAAQALPYHhds-------viNGLHVSTVIPTDLITI-------GG 114
AHC27412      492 TQYLSFMSV-KQWGA-AGqwstnySAIAYSEDNGENWYIAPSSVRTNf----------------GGNANfqqgafvrpGD 553
WP_011731164  140 ENYMMVTVT-KDLTPqTS-------RLVKADAAKSSWPTVPGSVREAsylggnqsqvsgyydpiPTPDS---------PR 202 Mycolicibacter...
AHC27720      103 ENYLLVTTT-EGLRPaSS-------RLVKADAAQGNWATVAGSQRPAgyagggqsqisgyydpvPTPES---------ER 165
WP_013806046  111 TVYLWAMRN-DGLHHvTK------TRIFTSNDHGEHWSPTRAA--WSgwrkga------nmqlitWERG---------GD 166 Hoyosella subf...
jgi:Snas_2970 156 TMYLHAMVN-KGLGNvVW------TEIWRSDDSGATWAHTGAK--FApdlhgg------mfqlltWGLG---------DD 211
jgi:Kfla_3477 150 SMYLHAMVN-KGLGNvVW------TEIWRSDNSGASWYHTGAK--FDpnldgg------mfqcltWGEG---------ND 205
WP_013020724  152 TMFLQVMVHgEKLGDvLR------SEIWSSKDEGESWQDTQAR--WAgdvhgg------rmqqltWALD---------DD 208 Stackebrandtia...
jgi:Gbro_0806 127 DLFLHVMVI-RGFPHvHW------TEIWRSSDGGVTWGHMGRDAVFGadlygg------faqswtWDFDp--------DD 185
WP_013827017  123 LLYLHAIVN-RGFGNvAW------TEIWQSADSGTTWHNIGTR--FParrhrg------haqcwsWDYDp--------DD 179 Mycolicibacter...
CAM02135      115 AMYLHVMVC-QGIGNvHW------TEVHRSTDNGETWQHTGAT--WPgdhhgg------lfqmltWAPG---------DD 170
AHC27412      554 GFVYSYGTPNGRQGQAFVSRVAEKDILDVTKYEYYsagssgwlfgiGAYssgWYRNDPGk----ASPVFgretgacgvak 629
WP_011731164  203 GWVYIVANNFDRSGPVFLYRVPPQDFTDRAAWQGW-----------SSVsgrWGDP--------ATALW----------- 252 Mycolicibacter...
AHC27720      166 GWVYIVADNFDRTAPVTLYRVPPQHFPDRAAWQGW------------STehgWGGD--------PTPLW----------- 214
WP_013806046  167 GYVYAFTTGFQRNKPLYLYRVAESSVLDKKAWTPWgw--------tKRRgwqWGNK--------ATPVL----------- 219 Hoyosella subf...
jgi:Snas_2970 212 GYVYLFSTGFQRDKPMILQRVPADKIADPAAYEPWgw--------kAEGgwaWGNP--------PSPVL----------- 264
jgi:Kfla_3477 206 GYVYVYSTGFQRNKPIILKRVRSTQIANPAAYEPWgy---------rDGrwaWGHP--------ATPIL----------- 257
WP_013020724  209 DMVYVFSSRFDRSVGFILHRVHKDAIADTNAYEWWgw-------deGTKkwdWNIGTPGevwtqPT-------------- 267 Stackebrandtia...
jgi:Gbro_0806 186 GWVYVMSSAFQSGSGMILRRVRPAGIGDRHLYETWgf---------rDGrwdWGNP--------PTVITpqg-------- 240
WP_013827017  180 GWVYVVSTGFQRNKGVILRRVRPADIGNPAKYSGWgy---------rGGrraWGRT--------PVPITppg-------- 234 Mycolicibacter...
CAM02135      171 GYVYAFSTGFQRDKGLILQRVPADRVADPGAWEGWgf---------rDGawaWGNP--------PTIAL----------- 222
AHC27412      630 aGNQVSEMSVQYNkTLGK----YVAMHGD--QF-NNIILRTSDRPEGGWSAPTVV-----------------MG-QQGGg 684
WP_011731164  253 -PDRVGEMSIRLI--DGK----AVLSYFN--ATtGNMEMRVADDPTQLGTAPVTTvvyasdwpdpaetlpppEVnRLAQ- 322 Mycolicibacter...
AHC27720      215 -GDRIGEMSIRQI--DGR----TVLSYFN--AGtGNMEVRVANDPTQLGSAPVTTvvfaapwpqrpedlpapDDnRLAQ- 284
WP_013806046  220 -TGQFGEISLRRV--ADR----FVLSWFD--AGnYQIRVAILTHPTNNLYRAPTRtvltgttw----daedhangRVAQ- 285 Hoyosella subf...
jgi:Snas_2970 265 -EGRFGELCLRPL--DGK----WVLTWFN--EGdYRIDGIIMDTPTSNLYEARREtllwgts------wgneddsHVAQ- 328
jgi:Kfla_3477 258 -SGSFGELCLRPL--GGK----WVLTWFN--AGdYRIDGIIMDTPTSNLYTAYRQtllygga------wgqendnHVAQ- 321
WP_013020724  268 -----GEMCLRRL--EGK----WVMTWFNasQGkESIDGLVFDKPNDDLTKAHHKqlilntp------wgqeddsHVAQ- 329 Stackebrandtia...
jgi:Gbro_0806 241 --elWRETTFRRL--RGTagvgWVLGGYC--ISdRGLSYRVLADPTDDVGARVKTmpiseisdw---gkedhpagRVAQ- 310
WP_013827017  235 --etWGELSLRRL-AAGT----WVLGGFV--SSrYALGYRVLDSPASELASVPLQlpvigcsw----dredhagsRVAQ- 300 Mycolicibacter...
CAM02135      223 -TGAYGELCLRPV--GGR----WLLSFFD--AGnYRIDVMNMALPTSNLYEAPRTtvlhgtaw----gredhacgHVAQ- 288
AHC27412      685 IYAPMMHPWspstLgTGteLYFNLSVWND-------YNVWLVK 720
WP_011731164  323 PYGGYISPAstldE-----VRVFISQWNTrprggtpYRVIQYA 360 Mycolicibacterium smegmatis
AHC27720      285 PYGGYISPAstldE-----LRVFVSQWNTaprggtpYRVLQYA 322
WP_013806046  286 LYGGYVIPGssleD-----LYLAVSQWNTgtn--kvYKTMVFH 321 Hoyosella subflava
jgi:Snas_2970 329 LYGGYIIPGstigE-----LHLAVSQWNTndg--wpYRVMQHR 364
jgi:Kfla_3477 322 LYGGYLIPGstlsD-----LHLSVSQWKTdag--wpYRTMQFR 357
WP_013020724  330 LYGGYIIPGstinD-----LHLVVSQWKTddh--svYRSMQHR 365 Stackebrandtia nassauensis
jgi:Gbro_0806 311 AYGGYIVPGssldTpGG--IHLAVSQWNTrth--wpYRVMQFA 349
WP_013827017  301 LYGGYVLPGsrvdRtGG--VGLLVSQWNTaag--wpYRVMQFR 339 Mycolicibacter sinensis
CAM02135      289 LYGGYIVPGstldD-----LHLVVSQWNTern--wpYRAMQFA 324
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