2P7V


Conserved Protein Domain Family
Rsd_AlgQ

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pfam04353: Rsd_AlgQ 
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Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ
This family includes bacterial transcriptional regulators that are thought to act through an interaction with the conserved region 4 of the sigma(70) subunit of RNA polymerase. The Pseudomonas aeruginosa homolog, AlgQ, positively regulates virulence gene expression and is associated with the mucoid phenotype observed in Pseudomonas aeruginosa isolates from cystic fibrosis patients.
Statistics
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PSSM-Id: 427888
Aligned: 45 rows
Threshold Bit Score: 159.68
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2P7V_A            1 MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKL 80 
IEC:ABF-0014923   1 MLKQLQRLTENVGGNYALIDQWLLARKHLLLAYYHLLSIQT----GKIPEARTLDEFCHHLVDYLSVGHFHVYERMLQEN 76 
Q6DAL9            1 MLNQLQSLTEYVGGNNALIDQWLQARKQLLVAYYHLVGIKPNKEALSLLDEEALDNFCQNLVDYLSTGHFHLYEKMLHEA 80  Pectobacteri...
WP_002445258      1 MLNQLKSLTERLNGNNTLVDQWLLQRKHLLIAWYNLVGLTPGKSSLAAIDEMALDAFCQGLVDYLSAGHFHIYARIIGEI 80  Shimwellia b...
Q32AG8            1 MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLGGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKL 80  Shigella dys...
wugsc:KPN_04377   1 MLNQLENLTERVGGSNELVDRWLQVRKHLLVAYYNLVGLKPGKESFMRLNEKALDDFCQSLVDYLSSGHFSIYERIIGEM 80 
WP_013024121      1 MLNQLDVLTKRVGGSNELVDSWLAARRQLLVSYYHLVGIKPKKEALTRLDEQALDNFCHNLVDYLSSGHFSLYQRLIGEM 80  Pantoea
WP_015699031      1 MLNRLERLTQRVGGSNELVDQWLHARKELLVSYCTLVGLKPNKEKHTPLNEKALDNFCHNLVDYLSAGHFHLYQRLIDEV 80  Rahnella aqu...
WP_015006731      8 Q-------KKERTQTSGLIRELLEERKQVWSSYCAVSGI--EEHKGQKPIEELLQDFCQLTVDYISLGHFGVYQRILAGN 78  Cycloclasticus
WP_014869798      1 MLEHCRNARERWGGVSDLIDRWLKERQDVLVRYCELSAE--NDYSQTESLRPKLVLLCEMLMDYVSAGHFEIYEQLVREA 78  Marinobacter...
2P7V_A           81 EGNGQ---LARAAKIWPQLEANTQQIMDYYDSSLEtAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLV 148
IEC:ABF-0014923  77 IMRNDr-kLTQASHFDVALRSNTQQIMDIYDSHLAfFIDPVDSQEFRQTLSGVGEALAMRFTLEDSLIRLM 146
Q6DAL9           81 ATHSEq-vLALSTQLDFALQNNTQQIMTFYDSHLAaAIDHDNCIEFQQALSSVGEALEERFTLEDNMIKQV 150 Pectobacterium atrose...
WP_002445258     81 KGNYA---QLATSQICPQLEANTQQIMAYYDLHLEsALEHDDFAEFQQALSGLGEAMETRFALEDKLMLma 148 Shimwellia blattae
Q32AG8           81 ESNGQ---LARAAKIWPQLEANTQQIMDYYDSSLEtAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLV 148 Shigella dysenteriae ...
wugsc:KPN_04377  81 EGDTP---LLAATRLYPQLEANTQQMMDYYDTCLEnAIDHDNYLEFQQALSDIGESLEARFALEDKLIALA 148
WP_013024121     81 DGTSP---LLAATQIYPSLEANTEQLMKLYDGHLQqAIDDDNYVTFQNALSEVGEALEGRFTLEDKLIQMA 148 Pantoea
WP_015699031     81 EGANSp-iKLQAAKIYPALELNTEAIMAFHDSYTEnDIDDDNAFAFHYALSDIGEALDARFQLEDQLITLA 150 Rahnella aquatilis
WP_015006731     79 ERRKSv--LAAAERIYPSISKATETVLDFNDKYQT-LTPAMILNELASDLSSVGENLANRIELEDQLIGEM 146 Cycloclasticus
WP_014869798     79 REFNDdegLELVAKVYPRITETTQVILDFNDKIDGrELSESEMQALFTELSRVGETLASRFELEDLLIAHL 149 Marinobacter sp. BSs2...
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