4I98


Conserved Protein Domain Family
SMC_ScpB

?
pfam04079: SMC_ScpB 
Click on image for an interactive view with Cn3D
Segregation and condensation complex subunit ScpB
This is a family of prokaryotic proteins that form one of the subunits, ScpB, of the segregation and condensation complex, condensin, that plays a key role in the maintenance of the chromosome. In prokaryotes the complex consists of three proteins, SMC, ScpA (kleisin) and ScpB. ScpB dimerizes and binds to ScpA. As originally predicted, ScpB is structurally a winged-helix at both its N- and C-terminal halves. IN Bacillus subtilis,one Smc dimer is bridged by a single ScpAB to generate asymmetric tripartite rings analogous to eukaryotic SMC complex ring-shaped assemblies.
Statistics
?
PSSM-Id: 427697
Aligned: 95 rows
Threshold Bit Score: 106.477
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
4I98_B          5 AKIEALLFVAGEd--GIRVRQLAELLS-L---PPTgIQQSLGKLAQKYEkDPDSSLALIET-SGAYRLVTKPQFAEILKE 77 
jgi:Fnod_1463  11 ALIESIIFAS-R---GISKENISTLT--Ei-pLEE-IELLINEIKEDYS-SENHGIELREI-EGYLRFYTKPQFSSIVSK 80 
jgi:Tlet_1517   7 AIMEALIFAS-K---GMTVQQLAKIA--Ei-tEEQ-AEKALYELSRHYG-GEEHGVELKKI-GDVYRFYTKPEYSEFVKK 76 
Q9WYW4          5 AAIEALIFAS-N---GITLERLIKILEkD---PEE-IKRALEELKKEYE-DEAHGVVLREV-NGRYRFFTKPEYAGFVSK 74  Thermotoga mar...
Q9HKK2         10 RKVEAILYSSRS---PVSIKLISQIL--Sa-dPLS-VRKAVINLKKNYE-KRDGALEVASY-GYKYRIQLKSQYFSEAYA 80  Thermoplasma a...
Q6L0G6          6 RKVEAILYSCEE---PLKVSDIADYLkv---sNDD-VIRAMKLIARSYN-EINSTLEIKKI-GNKYKIQLSNDFNDVVYP 76  Picrophilus to...
A0B6Q9          5 ALVEAMLFAAGR---PLSVEEISGLS--Gl-dAKD-VLDAANSLLREYA-SRGGGIEVRAV-EGSFVMQVRGDLAQSVAM 75  Methanothrix t...
Q5JDN0          8 ALVEAALFVAGR---PLSLKELSKAL--GiksLEY-LEKLIELIAAEYA-ERKSAIEVVRVlEDKYVMQVKQEYSQRVIH 80  Thermococcus k...
O28692          5 KIVEAILFSSSE---PVDARELRKIT--Gk-dKVE-ILNAIGELIKDYE-SRDTSIEIIKV-GEKYLMRVKPQYAEYVER 75  Archaeoglobus ...
Q7UPG2        127 AIVEAALFVGHPenlPLTPPRLASIM--RgfsPEE-VVDIIDKLNASYR-AERQGMRIVEQ-DGGYRMVVAPDVESVRAA 201 Pirellula sp.
4I98_B         78 YSKApI-NQSLSRAALETLSIIAYKQ-PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEV-LGRPNL-YVTTDYFLD 153
jgi:Fnod_1463  81 VAKRrY-LGSLSSSQLEIAIFLAVRK-QATKLEIDSMRGKDSTNIIKQLLASGVIKRRK-----SGRTFI-YSLTETFKD 152
jgi:Tlet_1517  77 IGKTiY--SKLSAAQMEIVAAIILNG-PSTVQSLNEMRGKDSSAIVRFLHKSGILVRKR-----HGNSYL-YQLSENFKD 147
Q9WYW4         75 LSGR-K-YKNLTDTQMEVVALLLISG-PIPKSEIDAFRGKDSSAVLSSLQRMGIVRKKR-----KGKSYL-YQLSPSFVE 145 Thermotoga mar...
Q9HKK2         81 VSPP-----DISRSEMKVIANIAISDvGLSATAIKKIAHQRTDQILSHLEDMGLVKLIN-----KGNSKI-YTLGRKFES 149 Thermoplasma a...
Q6L0G6         77 FVKK-----DLDKRDIAMLSYIYGKP-GVIAGELRENFGYNFMESVKKLKAEKLITSHKYRNT-----FK-YHVTKNFYV 144 Picrophilus to...
A0B6Q9         76 VAPR-----ELDSSVIRTLAVIAYRQ-PIMQSELARIRGNKCYEHVRLLERMGLISASK-----KGRTRE-LRTTRGFAE 143 Methanothrix t...
Q5JDN0         81 LMPK----PDLRTGELKTLALIAYLQ-PVEQSKIIKLRGSQAYEHIKRLVEMGLVYAEP-----YERTKL-LGTTKKFAE 149 Thermococcus k...
O28692         76 FTVR-----EFDRGTLRTLAVIALKQ-PITLAKVAKIRGNKCYEHVKKLQERGLVKAEK-----KGRSTI-LTTTEEFAT 143 Archaeoglobus ...
Q7UPG2        202 FTGK-IrETRLNQSAVEVLSLVAYQP-GITSARVTDLRGRDSGSLLNQMVRRRLVEVKREPGEgSDKLVSrFYPAERLLV 279 Pirellula sp.
4I98_B        154 YXGINH-LEELPVI 166
jgi:Fnod_1463 153 ----ESmIEELVRQ 162
jgi:Tlet_1517 148 FLMIEEvLEQFEHL 161
Q9WYW4        146 STMLDEiLKEvsqk 159 Thermotoga maritima
Q9HKK2        150 YFGISK--EEFAKK 161 Thermoplasma acidophilum
Q6L0G6        145 RFNVKD-----DKK 153 Picrophilus torridus
A0B6Q9        144 YFGLQSaSPEFLRG 157 Methanothrix thermoacetophila PT
Q5JDN0        150 LYGFPE-ND--PVL 160 Thermococcus kodakarensis KOD1
O28692        144 YFGLDS-AE--PEK 154 Archaeoglobus fulgidus
Q7UPG2        280 LLGLET-IDDLPHV 292 Pirellula sp.
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap