Conserved Protein Domain Family
MCP_Sipho

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NF033847: MCP_Sipho 
major capsid protein
This protein is a phage major capsid protein, as reported in primary sequence submissions of a large number of Siphoviridae, many of which have hosts in the Mycobacterium and Gordonia genera of bacteria.
Statistics
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PSSM-Id: 468204
Aligned: 128 rows
Threshold Bit Score: 270.251
Created: 11-Oct-2024
Updated: 3-Dec-2024
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
RZF02816      30 AKASPaDLSEEIGSLFTELYGEGe-NVTPQTADQIELLAkvaDGV---EGVVQEAATRAARA----SEIGQRINDLQQNS 101
RTL24353      13 EDDDV-EVVDLTLLSEGELRERH--GLLGELIEELRAQPrtiEVVatiNALREERNEIVQAVrdltTLDSAEIEDLSIDS 89 
WP_116996396  14 GDDALeTLTTSIAAAAEELLSQD--EITDEVNDELERLA---DAR---DAITALTKERAAAA----AARQERRDSAAARF 81  Desertimonas flava
SDY15434       5 ltEGLaPAPSTA-------------KPSAESDSRLQYLI---------DNIT--------------SLSEYELQELIDIL 48 
AKJ72554      22 DAGNReELRADITAVYEEADADA--PEVDEMIVAMRALN---NFE---TMLETFERNAKKIE----SEETAKKEADAKAA 89 
AWN03541      12 SLPEItELRAAAVAAANELNALAddVITAEQTTELIALI---DNV---GTLSDRVTELEGS-----EATAAQLAAARAKL 80 
AMP54263      16 TRDELsTLNDELVAEFDALNPGDndDVNAETLEKLENLA---GRI---RSVRERSEQLATEA----EESRAKVRALREQL 85 
OFW55852      19 TGAELdQLETAIHDEFGELDEISddDITTAQIERMAALA---DGV---EAIRGDRQLRTEAA----QARAAERESLRTRL 88 
WP_119580446  17 SDEDLaALEGKAVAEFNRVNESD--AVDPETLQYAMRLT---DDL---DRIRGELRVREVRAeqqaSLQQSRVAEQLSQL 88  Streptomyces eu...
WP_030248098  17 GESELrELETNAVAEFDRVAGLQ--QILPEHISYSERLT---RDL---DRIRAELRVRAVRAeeeaATAQQEATRRMALL 88  Streptomyces sp...
RZF02816     102 S---GDTEPTaetiadtePADDETTSESAapamATDNTPavpPAAQPNSSPAPAAPaaqtpvAPASAAPASAAPALAT-- 176
RTL24353      90 Ad--PVEGES--------ATTEATEAEEPttqtEAEAPTlavVAEDTNAPQEDPVS------DQNEIMEAADEVVAEA-- 151
WP_116996396  82 AdpePEAEVDd------vPAAETAPDADP----EPETPV---AETEPDPEPDVVVP------DDASSIDDTAPAAVEPaa 142 Desertimonas flava
SDY15434      49 Q-----------------SRAEAAGGDPN----LSTREL---QSLASFSMLVKTEM------QRRNNGGAITASAT---- 94 
AKJ72554      90 E-----------------EVDKTDKVEAE----AETETEtetAEADKAEKTEAVAE------VTTDDATADVEATQES-- 140
AWN03541      81 AdigKDEAGTe------gADADAADADAE----GADADA---DAADADAENRELVL------ASAAGGTVPAGRTFTQ-- 139
AMP54263      86 NstkVDDSTD--------DGAQQGDETVNddgtVDVEAE---DDTATDMTKVAEVV------ASAVATGIAKAYAEDT-- 146
OFW55852      89 QsgdATEDTD--------GGDDSGDAGDA----DGVDAE---ADTGARTPALVAGG------RGRTDVRDVLTNPRDRl- 146
WP_119580446  89 QarvNGSPAA--------QAAAEQAPQVD----AESIAQ---ATAQGVTAALSAFM------LDRSGGRVRPDEIARRa- 146 Streptomyces eu...
WP_030248098  89 Rq--SVHVGE--------GGEGGDGGEGA-----APVTAggrVDLAALTEATAKGV------ASILFGDQAPEAVQRR-- 145 Streptomyces sp...
RZF02816     177 -EAPLVPLGTQQ-------ASALPa----------------lQEQPAGkfasfsLVAAADIPGFSTGqvMQgGLGDFARA 232
RTL24353     152 -LVASAGERPVA-------PAAQT------------------PERVRVa-----YVAGAGQNAFTQG--VDlDMAGLARA 198
WP_116996396 143 qVPAVSAATTEPaptpapaPAVAPekglaamsakrsrsttarPARADF------MTATAHALGGREGnpFD-NVLDLATA 215 Desertimonas flava
SDY15434      95 -TFVVPADRRPN--------RVGS------------------GSATAI------TASGVDLND---GdsLGhEFADA--- 135
AKJ72554     141 -EMAMAASAADV-------PEEHR------------------PVARPAvttratVGTDINISGLTAGadFS-NLGQVNDA 193
AWN03541     140 -RVADKNVVSGRneierdvNRILEq----------------sKGKELA------ITAAANIGGFSSGetLD--FTQLAEA 194
AMP54263     147 -IADVSNLNRRTrln--elSQYAPgest-----------tprSDSDTV------LVASADVPGFTKGgqLS-GTSELREA 205
OFW55852     147 -NVRLSAAKQHQtp----dTRIDMk----------------qSFGQTV------LVASADLSNFGNGaqMA-NMDDLVSA 198
WP_119580446 147 -TASLAETAQHA-------PTPQV------------------PTQRLA------ITASVDIPGVARGegLS-SLTALADV 193 Streptomyces eu...
WP_030248098 146 -VASLSQVRERA-------PQAKA------------------PNAQTMa-----VTASVDIPGVGAGqsLP-TLEALSEA 193 Streptomyces sp...
RZF02816     233 YESRMFPMIs-GGVNSGKDGe------------------rTRVGIARIRRE-LPEQ-------FRITNERDAEDVvRHAC 285
RTL24353     199 WDSKRHIQP--AGDAPVSAV--------------------VASLPAFEDTPgLPVEvl---thRNTAEQNDAIVAaAVAE 253
WP_116996396 216 ITKKRHSFSv------------------------------VPAGVKRDFVP-IASGmkeiehaVGGDLEQNFQVLrDLQV 264 Desertimonas flava
SDY15434     136 -MKRSASDPr-IG----------------------------KTQVAKLHVQ-RSADrtlttddPIATAAVFKAAAaEHAQ 184
AKJ72554     194 FVKKIEQVRt-GS----GGDg-------------------EKRSVATLIAS-IGEErq----lTRGDAFGNQAKI-DAAV 243
AWN03541     195 YAKRGKTFAs-RIENGQRRMagrkmlsrqartrsgltdgaERYSVARLAKP---DNafq--itQGMSSQGAWDVI-MKAA 267
AMP54263     206 FYNVARVLPv-SR----TGNp-------------------QVTPVASLQRT-FRNKi-----sARSSLGDIQNTI-KAAS 254
OFW55852     199 MTARARSLPd-SRNFAAKGDwt----------------rvPRYNVAQLRRQ-FRYNl-----dITSKPEDAWALM-QEAA 254
WP_119580446 194 TARKAKSMPvtSGQp-------------------------SEQLVASIRND-FSHSv-----dNRTTRGEMKDLIsYLTG 242 Streptomyces eu...
WP_030248098 194 FRAKAKAVPt-TQYGDRGAP---------------------RHLVASLRNQ-FEHTv-----dDRTSASTVEELW--HSM 243 Streptomyces sp...
RZF02816     286 D-ESRl--PGGSLVASAGWCAPSETLYDLCPI--RmTEEGIISLPQVQTRRGGIKFPADFDWSA---------------V 345
RTL24353     254 WrEAR---SGGPLARTAAICSPLDIIREIPEVgtD-ETPFASAFPSRPVGRLGFQFTQPASIAS---------------T 314
WP_116996396 265 G-------AE-ALVASGAGCAPYSPSYEFFRLaeP-QNPVEAGTPVVQAPRGGIRYIVPMSVAA---------------A 320 Desertimonas flava
SDY15434     185 YvAAQlaqPQ-ALVAAGGLGTPEAVDYAIAGFevA-DRPVRDALPSFTATRGGVRFVRPPTLAD---------------L 247
AKJ72554     244 A-------PQ-ALVASGGYCAPLPVNYDIFGVgsA-ARPVRDALPTFGATRGGIRYIAPPVLGA---------------Y 299
AWN03541     268 A-EGRl--KGNSLTAAGGWCAPSEIIFGFLEL--E-TAEGIMSMPEIGAPRGGIQFTKGPQLGD---------------L 326
AMP54263     255 D-------VN-VLLADGGWCPPAENSFNFFRI--V-CLDGEIDLPTVGMSRGSIQYPVSPDLGD---------------- 307
OFW55852     255 N-------PE-SLVAAGGWCSPSEISYDFYNI--V-ATDGMLDLPTTGIRRGGMRWPTSPSFGD---------------L 308
WP_119580446 243 P-DKQa-----ALVAGGGWCAPSETRYDFFNI--A-CEDGMIDLPTFGVTRGGISYPVSPSLADalaggtafagfaatlS 313 Streptomyces eu...
WP_030248098 244 T-QQRg--QADALLAGGGWCAPSEVTYDFFNI--AdTPVGLIDLPTVGVSRGGIRYPVSPSIGDvffqnagsnpasgfgG 318 Streptomyces sp...
RZF02816     346 WSSi--Gfh------lTEEE----VMA------GT------EKNCIEVPCPSeWPEYRMEVAGVCLRTPILMERGWPERV 401
RTL24353     315 NGAi-tVw--------TESN----QNSvdpddsAT------WKPCVNIACSS-PTEVKAEELVTCATVDSSTQMSSPERV 374
WP_116996396 321 AGAidiSa--------QDRDyepyDETtnpdglG-------PKACISVDCAD-IAEEEVSAVSQCVTFDNLRYKVFPEQV 384 Desertimonas flava
SDY15434     248 EGSv-gIw--------SMAN----DIA-------AvtdpavRKPILRVPMST-EVVVDLMAVTNRLLCGNTLARAFPEYV 306
AKJ72554     300 NDAis---------lwTAAN----DAN-------Ptn--ptKKPTLKVGCAE-ELTATADAVTLSLEFGNLMTRAFPELV 356
AWN03541     327 LIDtdlGwv------mTEAQ----AEA------GGf-----TKPVFDIECPD-WDEVRMDAVGWALRAGLLTNTTYPELL 384
AMP54263     308 IEGi--Twt------wTSAD----DESna--etGEp-----TKPCVRVNCPE-FQVTQAECDGFCVVVSNLLSSSFPEAV 367
OFW55852     309 ASSt--Glw-----hwNETQ----DIAaa---tGTaq--sgSKTCARVPCAS-FNEARLEGEGICITAGNLTTDAWPEQI 371
WP_119580446 314 NTStpfLw--------TEAD----DIAaa---tGSp-----TKPCVRVPCPD-FDEERLEAYGYCLTAGNLTDDAYPEAT 372 Streptomyces eu...
WP_030248098 319 FAFp--FsnasdpwlwTEAD----DIAtv---tGSv-----NKPTLRVPCPT-FDETRLEAYGVSLTAGNLTDDAYPEAT 383 Streptomyces sp...
RZF02816     402 EQFMAGALLIHAHKMNALRLWKMEQLS---------TKIPMPGPrpgaeegawmvdphgPG----A-----VESLLSMLE 463
RTL24353     375 AEFMHLLGVQRSRRREQYLLGKFDATA---------SAYTFAGT---------------YG----A-----LPSLIQAVA 421
WP_116996396 385 AAFLEDVAVQFASTKEVFYLDYIKGKS---------TAATSAGA---------------YG----A-----SRSLLRDWT 431 Desertimonas flava
SDY15434     307 TRITELALAVYARVAEQQLLTQIGALS---------TAVSGAAGeg-----------agVG----A-----TRVLLPLLD 357
AKJ72554     357 QRHNQLSLIQHARFAERTLLNKISAAS---------TKVTTSWN---------------QG----A-----ARDLLLAIT 403
AWN03541     385 RRYLALALIVHARRMNKLTIDRTRALI---------TQTMTLAS---------------VGavpsA-----TADFLDAIE 435
AMP54263     368 DNWLDLVQVLRARRTNARIIQQIVEGNldpetgvgiTPATQVDH---------------TGlagaT-----TGALLSSVE 427
OFW55852     372 ANFMRLVNAAHAHRVNAFMINRLVALS---------TSVTVCPTg--------------VG----A-----IMPILDAIE 419
WP_119580446 373 QNTLQLLMAAHAHVINARLIALMLARS----------TAATSIT---------------GG----AvtdaaAPRIYNAVG 423 Streptomyces eu...
WP_030248098 384 QNFIRLLRAAYAHVINARLISLMVARS------------TSAIA---------------LG----AankpaAQTLLNGVE 432 Streptomyces sp...
RZF02816     464 LQVQYVRYRDRlPQDATLEMIAPYWLRGILKSDLRKK-Igi-dnRw--sISNEMIDGYL-RNVGVNPQYVYDWQDAFehp 538
RTL24353     422 TLLPQLLYVER-EDVANYDLVLEPGHFAKLSYDETNK-A-----Y----TDPADVKAALaSALGLNVIILRDFKAASpf- 489
WP_116996396 432 HATVAYRKRHGmRRNAVINVLAPDIAIDIIKLDIALSnDrgwpgT----VSDAEVESVL-RSLGIVAIWYNDNPTGTtpn 506 Desertimonas flava
SDY15434     358 RAATGMRDRLRmAQDAPLQLVLPHWSKGILRSDLAMQePgd-arEg---VTDAELIGYL-AARNLAPTFALDGEAGQ--- 429
AKJ72554     404 RASAAYRNRHRiPRPVQLRALAPEWARDLVREDIASN-Lqi-enLa---VTDTTIDAWF-AARGLRISWHMDDTF----- 472
AWN03541     436 LGAMRIREQFSmGLRATVEGKFPLWARMVVRSDLSRR-Tgv-dmLs---VSDRQIDGWF-SERQISPEFVRDYQPINa-- 507
AMP54263     428 LSAEDYRARHGmCMESVLEVVMPSWMRGAVRADLANR-Edi-efLs---VSNAMIADWF-DQRNIRVQFVQDWQM----- 496
OFW55852     420 MQATDLRTKYAmMDGAVMEAVFPSWVFGLVRADLAKR-Ngl-svAdafgVTNAQIGSWF-SLRGISAQFVQDWQV----- 491
WP_119580446 424 MAATDYRARYGmCIDDVLEVVFPYWVRDVIQADLAWK-Agv-elGd---IPLSEVNRYF-TARNIAVQWVNDWQV----- 492 Streptomyces eu...
WP_030248098 433 LAAIDYRAKFAmREDAVLEVVLPRWTLAVIRADLAWR-Tkv-erEs---VSDAQITAWF-TDRSVRPQFVSDWQV----- 501 Streptomyces sp...
RZF02816     539 mNQGG-------FGGP--IPLKWPDRVKLMLYPAGTFFELSDEVINLDGVYDHASLIQNVYTGlFTEEGWQVGRRC--M- 606
RTL24353     490 qTPPT-------PGGAsaTLAEIPDANVVRIVPSGAYIYGSTGEESTGWQTDPQLARQNRQQA-FSVEWLMLAKHG--Gs 559
WP_116996396 507 qKFAG-------AQGAg-ALAVFPTSIVSYVYAPGTFVRLDGGTLDVGLVRDSVLNRTNDL-QlFMEEWIGMAKLG--F- 574 Desertimonas flava
SDY15434     430 -HFD--------VQDPg-PVNAWPTEIVSYMFPAGAFQFMDGGTLDLGIVRDSELNAANDF-EmFSEGFEAVLHRG--G- 495
AKJ72554     473 --TS--------QSNNa-ALNDLPSSIKFWIFAEGTFIFLDGGTLDLGVVRDSDLVGTNDYMT-FVETFEGIAKVG--I- 537
AWN03541     508 gAVTV-------EGGTa-NWTTMPTKVEFMLYPAGSYVRLAEDVIDLDTVYDQDNLTKNQFLAaFFEEGFNIVNTGanG- 578
AMP54263     497 -GDDEengeviqFPGSqtPLTQWPTEADYLIYAPGAIVRGQGLSLDLGVVRDSVLNASNDHVAaWSEDCWGLLKYA---- 571
OFW55852     492 -RTTGf------FGNSa-AITSWPTQVQFLMYPAGTFVRGNGLMLDLGVIRDSTLNATNDYTAaWSEEFFLVAMIG--H- 560
WP_119580446 493 -RGASq------FGNAt-KMTAWPTTVDFLIYAAGTFIHGNGMSLDLGVIRDSVLNETNDHTAaWSEEAHLIAKVG--H- 561 Streptomyces eu...
WP_030248098 502 -RGSGq------FGRVdtNMTAWPTSVDFMMYAAGTFLHGNGLQLDLGVIRDSALNAENDHTAlWAEEAHLVARVG--H- 571 Streptomyces sp...
RZF02816     607 DSYVIEMD--LCPNGLSGSHVPVAC 629
RTL24353     560 PAATISVT--AVGNGSRACCTTAFG 582
WP_116996396 575 ESVQLTST--INVNGAAPNYVTALA 597 Desertimonas flava
SDY15434     496 EAFRISQA--VTPSGISRAA----A 514
AKJ72554     538 ESLEVTAT--TGISPATGS------ 554
AWN03541     579 VKVTVALPnrFGVTGAAIIGDLAND 603
AMP54263     572 EVRAVSVA--LCASGETGARSVT-C 593
OFW55852     561 ESRVITVP--LCPNGATAALQTFAC 583
WP_119580446 562 ESRRYTVG--FNVNGSTSALLTGTV 584 Streptomyces europaeiscabiei
WP_030248098 572 ESRLYRAT--LAVNGSGSADQTLGH 594 Streptomyces sp. NRRL S-455
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