1VJE,1J98,1J6W


Conserved Protein Domain Family
LuxS
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pfam02664: LuxS 
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S-Ribosylhomocysteinase (LuxS)
This family consists of the LuxS protein involved in autoinducer AI2 synthesis and its hypothetical relatives. S-ribosylhomocysteinase (LuxS) catalyzes the cleavage of the thioether bond in S-ribosylhomocysteine (SRH) to produce homocysteine and 4,5-dihydroxy-2,3-pentanedione (DPD), the precursor of type II bacterial quorum sensing molecule.
Links
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Statistics
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PSSM-Id: 426910
Aligned: 131 rows
Threshold Bit Score: 189.223
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1VJE_B          6 NVESFDLDHTKVKaPYVRLAGVKTTpKGDQISKYDLRFLQPNQGAIDPAAIHTLEHLLAGYMRDHLEgVVDVSPMGXRTG 85  Deinococcus ra...
WP_014097222    8 NVESFNLDHTKVKaPYVRLAGVKEGiHGDVIRKYDIRFCQPNKEHMDMPGLHSLEHMMAEFARNYTDkIVDISPMGCQTG 87  Weizmannia
WP_013489278    6 NVESFNLDHTKVVaPYVRLAGTTEGvNGDKIFKYDIRFCQPNKEHMKMPGLHSLEHLMAELSRNHHSqIVDISPMGCQTG 85  Evansella cell...
jgi:Bsel_1584   6 NVESFNLDHTKVAaPYVRLAGKTTGaNGDTIYKYDLRFKQPNKAHMDMPALHSLEHMLAEFSRNHHEgIIDVGPMGCQTG 85 
I0JJR3          5 NVESFNLDHTKVKaPYIRLVGVTEGdKGDKIYKYDIRVKQPNQEHMDMPALHSLEHLMAENSRNHHDrIIDIGPMGCQTG 84  Halobacillus h...
Q8CUK0          6 NVESFNLDHTKVKaPYVRLVGVTEGaNGDKVHKYDIRIKQPNKAHMEMPGLHSLEHLMAENIRNHSDaVLDIGPMGCQTG 85  Oceanobacillus...
Q8Y7I9          6 NVESFNLDHTKVKaPFVRLAGTKVGvHGDEIYKYDVRFKQPNKEHMEMPALHSLEHLMAELARNHTDkLVDISPMGCQTG 85  Listeria monoc...
Q2FWC3          5 NVESFNLDHTKVVaPFIRLAGTMEGlNGDVIHKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDkVVDLSPMGCQTG 84  Staphylococcus...
BAK17237        7 NVESFDLDHTIVAaPYVRLAGTKEGaKGDVVTKYDIRLKQPNKEHMEMPALHSLEHLMADRIRNHSDaVVDISPMGCQTG 86 
O24931          7 NVESFNLDHTKVKaPYVRVADRKKGvNGDLIVKYDVRFKQPNQDHMDMPSLHSLEHLVAEIIRNHASyVVDWSPMGCQTG 86  Helicobacter p...

1VJE_B         86 MYMAVIGEPDEQGVMKAFEAALKDTAgHDqpIPGVSELECGNYRDHDLAAARQHARDVLDQGLKV 150 Deinococcus radiodurans
WP_014097222   88 FYFSVINLDDDGEVLDIIEKTLNDVL-HAteVPACNETQCGWAASHSLEGAKEIARKMLAKRDEW 151 Weizmannia
WP_013489278   86 FYLSIINDESYENVLNLLEKTLNDVL-EAteVPACNEVQCGWAASHSLDGAKEIAEKMLAKKDEW 149 Evansella cellulosilytica
jgi:Bsel_1584  86 FYMAVLNDESYENILQVLEKTLQDIL-EAdeVPACNELQCGWAASHSLEGAQSLAKEMLNMKKew 149
I0JJR3         85 FYLAVLNDDSYENILQVVENTLKDVL-NAteVPACNEVQCGFAASHSLEGAQELARELLNKRNEW 148 Halobacillus halophilus DSM 2266
Q8CUK0         86 FYLSLINHDDYDDVLTMIEKTLEDVL-QAteVPACNEVQCGWAANHSLLGAQEIAKEMLNEKAsw 149 Oceanobacillus iheyensis HTE831
Q8Y7I9         86 FYVSFINHSDYDDALEIIATTLTDVL-VAteVPACNEVQCGWAASHSLEGAKALAEEFLAKRSEW 149 Listeria monocytogenes EGD-e
Q2FWC3         85 FYVSFINHDNYDDVLNIVEATLNDVL-NAteVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEW 148 Staphylococcus aureus subsp. ...
BAK17237       87 FYVSFMNYDDYEGVLSILEKTVQDVL-AAtaVPACNEVQCGWAASHSLEGAQQLAKEFLAKRDEW 150
O24931         87 FYLTVLNHDNYTEILEVLEKTMQDVL-KAteVPASNEKQCGWAANHTLEGAKDLARAFLDKRAEW 150 Helicobacter pylori 26695
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