Conserved Protein Domain Family
DUF4446

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pfam14584: DUF4446 
Protein of unknown function (DUF4446)
This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 165 and 176 amino acids in length.
Statistics
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PSSM-Id: 464213
Aligned: 138 rows
Threshold Bit Score: 137.564
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Cwoe_0009   11 VAIAGCAVAVIALG---VASSVAVALRRVRRDQ-RAVLG--EGmRATDLVSHAAGLEREYRALHAFVEEaagrLHERMGA 84 
jgi:Tmar_2365   28 sgvlaGLSLVVALVaawRAAAAHRRLRSLERWL-RAPGHdgVAaTRQPDEPTLGDVLARLHRLEVAQDD----TGRRVAT 102
jgi:Daud_2225    7 LIGIVGLLALLNVI-------LLLAYRRMTGRL-RRLSHllRLtDRGSLDELVNTFSLNIEEINRRLDG----VAAWQRA 74 
jgi:Aaci_2938   13 IALFSGILAIICLV---IASVALSRSARLKRKF-NRLKE--VT-SAADLERVFEETKDAVRKLEMKLRE----AEEHLRI 81 
WP_015740096    12 LCGALGFLALLSFF---ISFFCIRRLQRLLNLQ-RQLAR-----QLEDPEFVF--RLAALNEDYQETKKllleLQKRQEE 80  Ammonifex deg...
WP_013077197    13 wVAAIGILVVLLWL---TVLVQGAGLRKTQKRYrQWV----GR-SGTDVEKLLPQTLERIQQLSEEVRR----LEVRIDY 80  Kyrpidia tusciae
jgi:Slip_2373   12 slsIAAALFALLIL---VNIITLWQVRAYRRRV-RVFETlfKDyCGPGIEDVL----EEIRRLEHENRRqihrLEERVES 83 
jgi:Acel_2106   11 IALGALAVAVLGGV---FSVIGHLRLRRMRRAYeRAFAGt----DGDALVSTVARYVEETAGLRADIAA----AQRRLTA 79 
jgi:Intca_0171  31 VAIGAAVVAVLALA---LAVGAQLRLARIRRDF-RALAGd----GSTDIARVAAGQNHRIDRIATEVSR----LREQVRT 98 
WP_015049208    16 ALGALSLLCLLLIF-------FNLRLLLWNRRL-QRLLR--G--GGESLDELLRETLVSCREAKAELNE----LRQWCRE 79  Thermacetogen...
jgi:Cwoe_0009   85 AEARLDGAIAYHALVRYDAYGEMSGHQSTSIALLDAQRNGVVLSSIMHRDAARLYAKQVHRGRGELELSPEEAEAVRLAL 164
jgi:Tmar_2365  103 MAEELARCVRHVAVVRFNAFPNMGGEQSFALALLDAEGNGAVITTLAGREDTRTYAKPITAGSSPYLLSEEEREAIRRAM 182
jgi:Daud_2225   75 ADETLASCARTPVLLRYRAFEGVGGDLSYSCAILDGKGDGVILTALHSQNASFSYGKPVERGRSVYQFSTEEQEAVDRAL 154
jgi:Aaci_2938   82 VEEALQSKVSTPAILRYNAFAEVGSDLSYSVALIDGKGDGVVITSIYGREDSVTYGKPVQGGDSPYMLTEEERAVIEEAL 161
WP_015740096    81 QEEKLRKCVRTPVLKRYNAFADVGGELSFSAVFLDGEGDGFILTGLYGRREARMYAKEVRRGAPQARLAKEEEEVLAAAK 160 Ammonifex deg...
WP_013077197    81 LEKSLRATLRTARVVRYNAFSDFGSDLSFSAAWLDGSGNGVILSSIYGRDESRIYAKPVQNGTSTYPLSEEEKRVLAEAI 160 Kyrpidia tusciae
jgi:Slip_2373   84 IEGRLPAMLSTLRVIRYKAFPEVGGDLSFSLALLSERGDGAVITGLHGREYSMVWAKPVQAFSSSYQLSEEEQAVLRMAq 163
jgi:Acel_2106   80 LSGDVARSLRHVAVVRYDAFGDMGGRLSFSAAILDDAGDGLVISAIHGRTETRTYAKGVRGGSSDQPLSPEEEQAIRFAL 159
jgi:Intca_0171  99 AEDDVRQSLRHVAVVRYDAFGDMGGRLSFSAAIVDDLGDGIVISSIHARSESRTYAKGVVGGRSSITLSPEEQQALAAAt 178
WP_015049208    80 LEQGVAKSLRRVGFLRFNAFSDKGSELSFALALLNNDGDGIVLCCLVGRDDCRLFAKPVVGGTSPYPLSDEEKAAIRMAs 159 Thermacetogen...
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