3QWU,2HVS


Conserved Protein Domain Family
RNA_ligase

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pfam09414: RNA_ligase 
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RNA ligase
This is a family of RNA ligases. The enzyme repairs RNA strand breaks in nicked DNA:RNA and RNA:RNA but not in DNA:DNA duplexes.
Statistics
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PSSM-Id: 430596
Aligned: 149 rows
Threshold Bit Score: 31.556
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3QWU_B           73 APFWVEEKVDGYNTRIFkygdnyyalsrggficpft--------------------------------------tdrlpd 114  Aquifex aeo...
XP_003712962    227 TRVQITEKLDSCPISIYfvrndspfakclpalhdfagkpdaqrrqqqlcvfphgrvgvcanrleyvcapgqrfwavverl 306 
WP_013766067    164 LSFIVTEKLDGTSFTAYqrdgkfgvcsrnwelspedp-----------------------------------nsywkvae 208  Haliscomeno...
WP_012790086    161 HTFYVTEKLDGSSVTYYmneglfgvcsrnldleasedn---------------------------------sfwkvaeke 207  Chitinophag...
jgi:Plim_0508   182 KELIVTEKLDGSSFTAFhyqsqfgicsrnqwidemdgtsky----------------------------vaiaesfhlre 233 
WP_015712919    162 EAYYITTKMDGTSCIVYcidgkigccsrnheikdekds---------------------------------lywapvyhy 208  Treponema a...
jgi:Sterm_2898  162 KPYYIATKMDGTSCTIYfnngqvgvcgrnkeykettas---------------------------------gywklahly 208 
3_pfamImport      1 DEFWAEEKMDGERFQLHyqklnskfilfsrkgidysqkffktiei--------------------lsklfkgniencild 60  
GAD98954        316 PTFWIEEKLDGERMQLHmapddsiqggkkfgfwsrkakdytyl-----------------------ygnglydenaaltr 372 
EPE04282        366 KEYWIEEKLDGERMQMHmveddavpggkrfcfwsrkakdytel-----------------------ygdglqnkrtaltq 422 
3QWU_B          115 lidlrildenpdLVICAEVAGpenpyiee---------sppyvkedVQ-------LFVFDfmk----------------- 161  Aquifex aeo...
XP_003712962    307 gipgrlaregrtAVVQGELVApdrgg----------------pggfYA-------FSLWTeg------------------ 345 
WP_013766067    209 etqleqklqrrnLAIQGEMIGegiqknly----------klrgqhlFV-------FHVFDi------------------- 252  Haliscomeno...
WP_012790086    208 niaaklaalgknIAIQGELIGegiqgnay----------gfrgqtaRF-------FNAFDi------------------- 251  Chitinophag...
jgi:Plim_0508   234 klaemskqlgfdLAVQGEMIGpgiqgn-------------kyrlefVTlr----iFNVVNl------------------- 277 
WP_015712919    209 glkekllalgknIVLTGELCGpgiqknkl----------rlpqyewYV-------FDYKEw------------------- 252  Treponema a...
jgi:Sterm_2898  209 kipekltglgknIALQGEYCGekiqknrl----------klqkpkfFI-------FNVYDi------------------- 252 
3_pfamImport     61 gemmvwnsqsktFKVKGEFIDvk---------------------nlVSsninnpcFVCFDilyinnkslidlsysdrlql 119 
GAD98954        373 hlkdafvdgvesIILDGEMITwdpeqdapvpfgtlkta-alseqrnpfssgprplFRVFDilylngqdltrytlrdrrna 451 
EPE04282        423 flegafaqgvrnFILDGEMITwdpkidkivafgtlktaalnaqtnphdgeaprpvFRVFDilylndqpltrytlrdrhma 502 
3QWU_B          162 --------------knEQGFLSQEEK-MELIEkynlphveilgrftaseegIKKIKEIlk----------rFNEEGREGV 216  Aquifex aeo...
XP_003712962    346 ---------------gKHGGFDGEETqRAALRrmgvplvpl-vgyraigefASSTGEMlakad-----grgfRGQLREGF 404 
WP_013766067    253 ---------------dRHRYFSFAET-EAFCQendlkvvp---lvnpdfhlPPKIEDLltlaegpsllnpqAI---REGL 310  Haliscomeno...
WP_012790086    252 ---------------dAYRYLGLEEF-TALIAsldlqtvp---ildlnytlPATLDEMltiadgasvlspqGKSVEREGL 312  Chitinophag...
jgi:Plim_0508   278 ---------------tTGMLLDFDQM-QEVIKslglvavp----flekvtlNHSIDELiklae---gksvlNSSTLREGI 334 
WP_015712919    253 ---------------nKGVYVSYEAM-VEGCValgvptvp---leeegehfSYTLDELlekar-----gkypSGLDKEGI 308  Treponema a...
jgi:Sterm_2898  253 ---------------dTATYYNYRDF-RDIIAhlgletvp---veeegesfNYSLDELlekan-----gkypSGLDKEGI 308 
3_pfamImport    120 vkehfktslgqfhilnQSKIRNVSEFtSYFNK---------------------------------------SLENNCEGI 160 
GAD98954        452 lqkaikpvhrrfeihpYEEAKSAAEIePLLRK---------------------------------------VVEEASEGL 492 
EPE04282        503 leravigiprrlevhpYEKATSPDVIePMLRQ---------------------------------------IVADSSEGL 543 
3QWU_B          217 VFKEDSER--------NKRAKYI 231  Aquifex aeolicus
XP_003712962    405 VLKnv---------keNIWVKVI 418 
WP_013766067    311 VLRta---------drKVSFKAI 324  Haliscomenobacter hydrossis
WP_012790086    313 VIRst---------drKISFKVI 326  Chitinophaga pinensis
jgi:Plim_0508   335 VLRPISETfepd-tggRLSFKAI 356 
WP_015712919    309 VVRhsr-------sphLVSFKVL 324  Treponema azotonutricium
jgi:Sterm_2898  309 VIR----SqentedgkFLSFKVI 327 
3_pfamImport    161 VLKQVSSTykpg-qrvNDWIKIK 182 
GAD98954        493 VLKNPRSPyrln-erhDDWMKVK 514 
EPE04282        544 VLKNPRSMyrln-srnDDWIKVK 565 
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