6JZB


Conserved Protein Domain Family
DnaJ_CXXCXGXG

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pfam00684: DnaJ_CXXCXGXG 
DnaJ central domain
The central cysteine-rich (CR) domain of DnaJ proteins contains four repeats of the motif CXXCXGXG where X is any amino acid. The isolated cysteine rich domain folds in zinc dependent fashion. Each set of two repeats binds one unit of zinc. Although this domain has been implicated in substrate binding, no evidence of specific interaction between the isolated DNAJ cysteine rich domain and various hydrophobic peptides has been found.
Statistics
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PSSM-Id: 459904
Aligned: 1238 rows
Threshold Bit Score: 44.4714
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6JZB_A       155 CRTCNGSGakPGTSP----VtCGRCHGAGVINVDTQTPLGMM-RRQVTCDVCHGRGKEIK--Y-PCTTCHGTG 219
WP_013908856 145 CDFCKGLGydPEKGV----KtCEVCKGTGR----VTYTEGFF-RISYTCPDCKGKGKAY---IaRCEKCKGSG 205 Thermodesulfobacterium...
ESS30342     490 CDCCEGTGgkdg----qkaTaCTACDGKGAIVKTTTTNVGIM-RTSQTCQACRGSGEEAR--L-RCSNCSGSG 554
XP_001609996 307 CPDCNSSKsaQQKYI----SrCNKCSGRGM-ITKNQRTPFGYiSTSRTCMQCQGRGMAR---IqDCTTCNNSG 371
Q4N5K9       270 CNFCNYND----DSMnefiDqCNVCKGQGMETKEKRTKNGFF-RSSRTCTKCRGTGYQR---LkDCNKCDNTG 334 Theileria parva
XP_007411595 133 CEKCHGFGynRDARP----NmCQRCSGQGF-TIRVIPLNGIFaSSPIVCTSCEGLGAKIRseD-QCSSCNRTG 199
XP_005811008 236 CPRCGGRGnePGTRVs---Q-CGYCSGSGVESVNT----GPF-MMRSTCRRCGGKGTIII--T-PCALCRGSG 296
CDS42390     185 CTTCEGSRcqPGTGMt---T-CPNCSGSGHETVST----GPF-VLRSTCRRCSGTGSVVR--Y-PCRACNGTG 245
XP_002125030 230 CPRCDGKGnePGTKIs---K-CGFCGGSGMEQVVT----GPF-VMRSTCRKCGGTGKLVT--F-PCVQCGGRG 290 vase tunicate
XP_026693393 230 CPRCDGKGnePGTKIs---K-CGFCGGSGMEQVVT----GPF-VMRSTCRKCGGTGKLVT--F-PCVQCGGRG 290 vase tunicate
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