Conserved Protein Domain Family
FapA_N

?
pfam20250: FapA_N 
Flagellar Assembly Protein A N-terminal region
This entry represents an N-terminal region of the FapA protein and its homologs. This region is found in multiple copies in some proteins. Members of this family include FapA (flagellar assembly protein A) found in Vibrio vulnificus. The synthesis of flagella allows bacteria to respond to chemotaxis by facilitating motility. Studies examining the role of FapA show that the loss or delocalization of FapA results in a complete failure of the flagellar biosynthesis and motility in response to glucose mediated chemotaxis. The polar localization of FapA is required for flagellar synthesis, and dephosphorylated EIIAGlc (Glucose-permease IIA component) inhibited the polar localization of FapA through direct interaction.
Statistics
?
PSSM-Id: 466401
Aligned: 95 rows
Threshold Bit Score: 78.0178
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
jgi:Cbei_1855 157 ISVNISVDKMKGYIkveykpayvyKLRDK-----PMAKDLilkamkveedypkkyTLTEIKEILRQNKI-TDGIIYKNLI 230
WP_012198504   16 TKVDLRYDKMEAYI----------TLYAP-----VGKDRY---------------TKEMIYEILRFHHV-IYGIDEEVVN 64  Lachnoclostrid...
jgi:Cthe_2410  75 ISVELSSDELKAYI----------RLCVEewefsGDARVK---------------LMEEISKSLEKAGV-VFGIKEDVLL 128
WP_003516112   74 IAITVTPDELKAFV----------TFNLPreeldIKNREN---------------LIKETYQVLKKKNI-NFGIKKELFF 127 Acetivibrio th...
jgi:Ccel_0028  75 ISIEVSGDELRAFV----------TVNVGqpevlGTE------------------IVKEVVLELNRRGV-VYGIKKDVLL 125
Q0SNP4        180 MMVQISENSMSVTI----------EFTAPg----INGAEI---------------FSQDIFNILRKYGViDIAILKDKVA 230 Borreliella af...
Q1NU26         78 LLQRLKRDEPEPRV----------RLD----------------------------FTVDYDPAPHRRQV----------- 108 delta proteoba...
Q7MSH2        100 FSLRLGEDFRELFL----------TLHKGs---qITYNAV---------------FLEELFERVRAQKAiMRVLFRQEAK 151 Wolinella succ...
WP_002849260  111 VVASIKEDSNVKYY--------------------PSFERD---------------LINFIQKKLLKANI-LIGIRDYIML 154 Campylobacter ...
Q0PC82         88 FTVKLRSNSNLTHLk--------aSINLTenfkyYPNLKFd--------------ILQNIYKIMIKQKFlILRLDKNLFD 145 Campylobacter ...
jgi:Cbei_1855 231 E---ACALGNGE----------EMLIAEGIGAIDDTPNEIKVLFDI-GEKRIVNENSNe-KIDYRNVYSISS--ITEGQV 293
WP_012198504   65 K---LCEKPCYGk---------EILIAKGKEEVDGKDGYFVYFFDTrVDT--KPRILEdgSVDYFAMTRIVT--VSQGEI 128 Lachnoclostrid...
jgi:Cthe_2410 129 Dglc---------------nnkQILIAEGIPPEHGEDAVIRM-YEIkKAK---PAIKEdgRVDHYELNLINK--VKTGDW 187
WP_003516112  128 Gdle---------------sgkKYLIAEGVPAVDGEDCKIRM-YELeEPR---PEIREdgKANYYELKLINK--VKAGDW 186 Acetivibrio th...
jgi:Ccel_0028 126 Nlva----------------gkTVLIAEGEPPQNGVNSQNRL-YQIkEAK---PEIKEdgTADHYDLNLINM--VSAGEW 183
Q0SNP4        231 K---FVDYPVYGe---------PIELAKGLEPVKGQDSYIDFIVD-----------ENn-RLGEYEVSSIGFrnVVEGEE 286 Borreliella af...
Q1NU26        109 ----IVDLARDR----------TRLAVKGRPPKDGIPGFIREKGRYaAERRARQHSG---RMDHYTTGEFVE--TKAGEV 169 delta proteoba...
Q7MSH2        152 ErerIASLLKELqnlpfldkdyEILLAQSAGGGRCVEATLILHF----------------QEDPALQGRFPT--IKEEML 213 Wolinella succ...
WP_002849260  155 ReinKVTSILRIkeii--dkafTFVVVTGVDPVVAVDDNMIFYYKSkLKNSEKNKDD---KVNYSNRGFVQG--VTEGEV 227 Campylobacter ...
Q0PC82        146 KiddFILSIQKSpsi----keiELEIAKGVDKIEHKSDEIIYHRDVnEECFDE-------NINYDEGNYCKP--IEKNEL 212 Campylobacter ...
jgi:Cbei_1855 294 LA-EIIPGKNGQDGKNICGEVL---KKKTVKSRPIKI-GDGCKV--EG-NSI-I-ATKTGRPSSK-NG 350
WP_012198504  129 IV-RYHKAIQGSNGIDVCGSIR---YGNIGRDLPPLK-GKGFKLs-DDrLIY-T-ALITGKIEVS-EG 187 Lachnoclostridium phytofer...
jgi:Cthe_2410 188 LG-ERIDPTPGTAGKSVKGNPI---PARPGRNYPLHYdKNSVREerKGgVTY-LyALKSGAVHYE-GD 249
WP_003516112  187 LG-ERIDATEGFPGKTVYGTTI---HPVRGKNYPLSYdKNTVYEvvQNkKVV-LySKIDGAVHYD-GN 248 Acetivibrio thermocellus
jgi:Ccel_0028 184 LG-EKIHATPGKEGKTVYGNPI---KPLPGKDYPIFFdRKTVKAveEEgKTT-LyATRNGAVYFA-GD 245
Q0SNP4        287 LA-RIIPFGKGVDGYTVFGKVL---KSESGQDINFVL-GENTF---RDgYKI-R-AKCNGYMSVS-DG 343 Borreliella afzelii PKo
Q1NU26        170 LAlIDNTKIKGEPGIDIRGMVV---KPQTAPSYQIRL-GEGVSKreKEsGKLeLvSEFTGLVKTNyDG 233 delta proteobacterium MLMS-1
Q7MSH2        214 LA-TFLKPQKGGAGRDCLGNYIppkEPSASAQNPLRI--DESIEerDEgNKInYyAKESGYLLFEeYR 278 Wolinella succinogenes
WP_002849260  228 II-EYIKPKTGIAGRNVKGDVIsvnEPKILIKEKINV-SQNIDVkeDDdSIK-YiAKKNGYVNEEkGT 292 Campylobacter fetus
Q0PC82        213 LF-EYIYRILGKEGRNLRGEILh-lNPIAFLDNPFII-KDESIYteELeDRIkYfSANYGFLNKDhTG 277 Campylobacter jejuni
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap