4LZJ


Conserved Protein Domain Family
TIGR00274

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TIGR00274: TIGR00274 
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N-acetylmuramic acid 6-phosphate etherase
This protein, MurQ, is involved in recycling components of the bacterial murein sacculus turned over during cell growth. The cell wall metabolite anhydro-N-acetylmuramic acid (anhMurNAc) is converted by a kinase, AnmK, to MurNAc-phosphate, then converted to N-acetylglucosamine-phosphate by this etherase, called MurQ. This family of proteins is similar to the C-terminal half of a number of vertebrate glucokinase regulator proteins and contains a Prosite pattern which is shared by this group of proteins in a region of local similarity. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Statistics
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PSSM-Id: 272991
Aligned: 5 rows
Threshold Bit Score: 484.731
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4LZJ_A  12 LITEQRNPNSVDIDRQSTLEIVRLMNEEDKLVPLAIESCLPQISLAVEQIVQAFQQGGRLIYIGAGTSGRLGVLDASECP 91  Haemophilus influenza...
P76535   6 MITEGSNTASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILDASECP 85  Escherichia coli K-12
P44862  12 LITEQRNPNSVDIDRQSTLEIVRLMNEEDKLVPLAIESCLPQISLAVEQIVQAFQQGGRLIYIGAGTSGRLGVLDASECP 91  Haemophilus influenza...
P73585  12 LLTEQTNPQSQNLDQLSSLELVDLFNQQDQLTVTAIAGAREDLAAAIEIISDALAKGGRLFYIGAGTSGRLGVLDAVECP 91  Synechocystis sp. PCC...
Q45582  10 LTTESRNSQTVEIHKANTLGILKMINNEDMKVAAAVQEVLPDIKTAVDCAYESFQNGGRLIYTGAGTSGRLGVMDAVECP 89  Bacillus subtilis sub...
4LZJ_A  92 PTFGVSTEMVKGIIAGGECAIRHPVEGAEDNTKAVLNDLQSIHFSKNDVLVGIAASGRTPYVIAGLQYAKSLGALTISIA 171 Haemophilus influenza...
P76535  86 PTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGGVNDLKNINLTAQDVVVGIAASGRTPYVIAGLEYARQLGCRTVGIS 165 Escherichia coli K-12
P44862  92 PTFGVSTEMVKGIIAGGECAIRHPVEGAEDNTKAVLNDLQSIHFSKNDVLVGIAASGRTPYVIAGLQYAKSLGALTISIA 171 Haemophilus influenza...
P73585  92 PTFCTPSELVQGILAGGASALLRSSEGLEDIAADGAQAIADHRITQLDVVVGITAGGTTPYVHGALDAARARGTKTIFIA 171 Synechocystis sp. PCC...
Q45582  90 PTYSVSPDQVIGIMAGGPEAFLQAAEGIEDSEEAGAEDLRNIQLTSNDTVIAIAASGRTPYAAGALRYARKVGAHTIALT 169 Bacillus subtilis sub...
4LZJ_A 172 SNPKSEMAEIADIAIETIVGPEILTGSSRLKSGTAQKMVLNMLTTASMILLGKCYENLMVDVQASNEKLKARAVRIVMQA 251 Haemophilus influenza...
P76535 166 CNPGSAVSTTAEFAITPIVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVNIVKNA 245 Escherichia coli K-12
P44862 172 SNPKSEMAEIADIAIETIVGPEILTGSSRLKSGTAQKMVLNMLTTASMILLGKCYENLMVDVQASNEKLKARAVRIVMQA 251 Haemophilus influenza...
P73585 172 CVPESQAPCQADVNIRLLTGPEILAGSTRLKAGTVTKMALNILSTGAMVKLGKVYGNRMVDVAVTNRKLEDRAIRILRDL 251 Synechocystis sp. PCC...
Q45582 170 CNENSAISKDADHSIEVVVGPEAITGSTRMKAATAHKMILNMISTAVMVKIGKVYENLMVDVNVSNKKLKERAISIIQSL 249 Bacillus subtilis sub...
4LZJ_A 252 TDCNKTLAEQTLLEADQNAKLAIMMILSTLSKSEAKVLLERHQGKLRNALS 302 Haemophilus influenzae Rd KW20
P76535 246 TGCSAEQAEAALIACERNCKTAIVMVLKNLDAAEAKKRLDQHGGFIRQVLD 296 Escherichia coli K-12
P44862 252 TDCNKTLAEQTLLEADQNAKLAIMMILSTLSKSEAKVLLERHQGKLRNALS 302 Haemophilus influenzae Rd KW20
P73585 252 TDLNREEAAELLVASGQRVKLALLMHWSGLSAESAQAQLDRHGGNLRQAMD 302 Synechocystis sp. PCC 6803 substr. Kazusa
Q45582 250 TNASYDTARYTLEQADHHVKTAIVMLKTSTDQKQAQTLLDEANGFIDKAIE 300 Bacillus subtilis subsp. subtilis str. 168
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