Conserved Protein Domain Family
rep_pAB02_ORF2
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NF038291: rep_pAB02_ORF2 
plasmid replication DNA-binding protein
This uncharacterized protein, with an N-terminal DNA-binding helix-turn-helix domain, occurs in replication regions of a large number of Acinetobacter plasmids. The founding members of this family, AAR00518.1 and WP_000839337.1 from plasmids pAB02 and pMAC, are referred to as ORF2 there, sitting adjacent to RepM, which in turn is adjacent to the DNA repeat region at each plasmid's origin of replication.
Links
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Statistics
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PSSM-Id: 468456
Aligned: 36 rows
Threshold Bit Score: 105.874
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_004779311   2 AKLSLSEVSKQFNVDRSTIYRAVRNGRLS--RSSDG--QFDIAEIIRCFGEP-----------EQVSQPNESAKQGS--D 64  Acinetobacter s...
WP_004676224   2 AKLSLSEVSNRFNVSRSTLYRAIKEGRIS--RSADG--LFDIAEVIRCFGEPik--------kHEKKQEVDQSKDDA--- 66  Acinetobacter
WP_001096621   2 AKLSLSEVSKRFNVSRSTLYRAIKEGRIS--RNADG--YFDVAEVIRCFGEPsk--------kHEQNQEIDKPKDDT--- 66  Acinetobacter c...
WP_001096622   2 AKLSLTEVSKRFKVSRSTVYRAIKEGKLS--RSADN--QFDLAEVIRCFGEPvi--------kASPEEQSKAPVKDD--- 66  Acinetobacter c...
WP_017386458   2 ARITVTQASKDFNISRNTLYKKIKQGHLT--KDSNG--LLDVNDLIRVIGAHtests--knvtLNTSDIQSVSSDTQ--L 73  Acinetobacter
WP_005020626   2 ARISINKASQDFHISRNTLYKHIKQGKIS--KDADG--KLDTADLVRLYGTHvst-----qqeLTTVNSSKPDEIVQ--L 70  Acinetobacter
WP_004884388   2 SNISINQASKLFKVSRNTIYARIKKGEIT--KNSDG--TVSVQDVMRLFGNKadkk----ateQAVTELLNSTNNTEqlI 73  Acinetobacter c...
WP_018680069   2 SKLSINQASKLFKVSRNTIYARIKKGDMT--KDSEG--LVSAQDMVRLFGNKtdkk----ateKAVTELLNSREQT---V 70  Acinetobacter t...
WP_004869127   2 SLLTIVEASKQFKVGRTTIYKAIKRGDLTpqKNNDGvqVIDAQDMIRVFGSSkksvsptisenSTQPVSGNSGNNEDl-L 80  Acinetobacter g...
WP_004650372   2 SLVTIVEASKQFGIGRTAIYKAIKRGDLTakKNNDGvqVVDAQDMVRLFGSSrkan---vsivVSGNSMLEKQQDSEqvI 78  Acinetobacter b...

WP_004779311  65 AATQKLIS-HLENEVKKYQEREER-LMQQIDRMQTLIElkSVAPSTAT--PHPDTTACDTQTLQREKTYQdtenkqnlyk 140 Acinetobacter s...
WP_004676224  67 -DLRQLVD-FMKKEIESYKDREKR-YLDQIDRFQLLLGhkESEEKMSH--DTPNRHFNETPCDNNDDSSEsienksiepn 141 Acinetobacter
WP_001096621  67 -DLRQLVD-FMRKEIDSYKDREKR-YLDQIDRFQLLLGhkESEEKMSH--DTSVRQTNDTPCDNNHETHKdtvnqefyst 141 Acinetobacter c...
WP_001096622  67 ADLRQLVD-FMKREIESYKEREQR-YLDQIDRFQLLLGhkESSEKVSH--DTPVTRSNDTPCDTFNDTPEpidtqamiqn 142 Acinetobacter c...
WP_017386458  74 QQAKSEVE-QLKQLLAQ--------KEIFINQLQQQIA----------------DLRQDK-------------------- 108 Acinetobacter
WP_005020626  71 EQLKSENE-QLKKHIAI--------SEMRINELKQQLD------------YVKQ---NESWLKEQL-------------- 112 Acinetobacter
WP_004884388  74 EQPQINNEqLLQQKIEQ--------LKVQIEQLEKQLEy---------------VKANEAWLKQQLDQ------------ 118 Acinetobacter c...
WP_018680069  71 QGSEQEVA-HLKSNNEQLLEQQIEqLKAQVEQLEKQLEy---------------VKANEAWLKQQLDQ------------ 122 Acinetobacter t...
WP_004869127  81 RELREQVK-ELKQDKEFLKQEISS-VRKDFDDYKLMITykGNL-----------SSVETVETVPETSRNS---------- 137 Acinetobacter g...
WP_004650372  79 QELREQLK-ELKQDKEFLKQEISS-IRKDFDDYKLMITykGNLSSVETeeTVSKNEKNNVGVQEKHNGIQ---------- 146 Acinetobacter b...

WP_004779311 141 nvAKSVapstAMPHPNATACDTLTLQRATlqnvavPQPKKRGLFGRVLN 189 Acinetobacter sp. NIPH 899
WP_004676224 142 slSHDT----VTRHTSEAPKNVSQTHHET--------RKKRSLFGRVLS 178 Acinetobacter
WP_001096621 142 esPHDT----PLTHLNEAPQNISKTHHET--------KKKRGLFGRVLN 178 Acinetobacter calcoaceticus/baumannii complex
WP_001096622 143 etSHDT----PLTRLNDAPRDTFETSHDTl----kKQPKKRGLLGRVIN 183 Acinetobacter calcoaceticus/baumannii complex
WP_017386458 109 ----------EQLYNQINQKRL---EHKK------------GLLGRFFG 132 Acinetobacter
WP_005020626 113 -----------------DQKRI---EHAE--------TRKKGLFNKLFG 133 Acinetobacter
WP_004884388 119 ----------------------KLIEHKE---------SKKGLLSKLFG 136 Acinetobacter calcoaceticus/baumannii complex
WP_018680069 123 ----------------------KLIEHKN--------SEKKGLLSKLFG 141 Acinetobacter tjernbergiae
WP_004869127 138 --FEEQ----EKQPKEQAETAIDEPKIEE----------KKGFFKRLFG 170 Acinetobacter gerneri
WP_004650372 147 --PETP----NKARVEDSKKDVLLAEEQL--------KLKKGFFRKLFF 181 Acinetobacter bohemicus
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