Conserved Protein Domain Family
T4SS

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pfam07996: T4SS 
Type IV secretion system proteins
Members of this family are components of the type IV secretion system. They mediate intracellular transfer of macromolecules via a mechanism ancestrally related to that of bacterial conjugation machineries.
Statistics
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PSSM-Id: 429777
Aligned: 36 rows
Threshold Bit Score: 113.209
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
tigr:CHAB381_0179  27 GIPV-VDAAANAQMTTQNLKQIAewakeakrwvdTTTHYSAQLNAYAKQL-------ATQSGVrdvTSFLEEAKdVYD-- 96 
WP_012738144       30 eIPT-ISPAELAQQVTHAKQQSRea-------vaQLKKAKEAIAQTKSQYdhyqkliQGNSKL---GDFLNDPV-VNNli 97  Candidatus...
zhongguo:PT7_1774  25 GIPT-VDAATIAQLQEQLLTARD-----------QLKNLTDQLATAKSQLaa----fTQSSGY---GNVVGNAD-IRNql 84 
zhongguo:PT7_0317  26 QIPV-TDGASITARAAQHAESLAky-------leQIATLKAQLESAHRQYea----iTGARNL---GDILNNPT-IRNsi 89 
WP_000857358       22 GIPVaVDADPMRDVqwaqel---------krwmeTARHYQSQIQAYKDQL-------ATATGVrdiADFVDQAKgLKA-- 83  Enterobact...
ACQ67974           26 GILV-FDATSKMENARqwakea-------kqwmeTVEHYKAQMNVYKDQL-------ATSTGLrdiQGLLEQGKsLQS-- 88 
WP_013318594       22 GIPV-FDAVSNTESINqwmqkl-------kqwqeTVTHYKDELDAYKQQL-------ATATGIrdiQGFLREAKsLKG-- 84  Dickeya da...
WP_015696806       22 GIPV-FDAVQNTESMNqwiqkl-------qqwqeTVTHYRSELDAYKQQL-------ATATGVrdvQAFLREAKsLKT-- 84  Rahnella a...
CAZ15846           28 GMPV-VDIAAIEQAIQ------------------QVSYLQQQLLQMKNQLna----mTGDRGM---AGILSGQN--RNyl 79 
WP_112178923       28 GVPT-VDVAAIAQMIQQFQMLEK-----------QLTNMQDQLKQAEQQVna----vTGKRGMek---------mLRNea 82  Rhizobiale...
tigr:CHAB381_0179  97 ---------EAKKVGTTLGElkdfknsgKDSISSKVKKLMDKFFEYDYCkdivdvdkttq---nicyqkrsanIEDIVFY 164
WP_012738144       98 pm---gdweDIYN---------------------------DIESLPNLRqrygltsvdp-----evqkafdqlLMKAGTL 142 Candidatus...
zhongguo:PT7_1774  85 raalpsnaqSLLDRSG------------GSSLDGDVGRITDEVmapvnfqkdrq---------slsrrslnieATSKAMS 143
zhongguo:PT7_0317  90 pa----dvrVVLRRGESS----------IGSIQHSVNRIRDEErltgnyavdsq---------alsrrvedlgLRSQALL 146
WP_000857358       84 ---------DLEKLRKPGQAlnd--lllSGGSSGQFDALYEKYKIFDTCntaqsgsyan-----vckqqvinkAIQLEQT 147 Enterobact...
ACQ67974           89 ---------EIKTLQNQGISlndl-ltsDNPPRGALDSLYHKYKSFDVCgdstsssklpasylnackqetankGYMIEQT 158
WP_013318594       85 ---------DIDALRKNGISlddlltnpDGSYSSALQGLYKKYQSFDSCnpsrsslryq----dsckqlllnqALAIENT 151 Dickeya da...
WP_015696806       85 ---------DIDNLRQNGISlddllsnqSGSYSSELNSLYNKYKSFDTCnpssaspryl----dsckqmilnqAVAIENT 151 Rahnella a...
CAZ15846           80 pa----dwnSAMNVLNSGGGs-------FGSLASAAQQIKQMQSVLSSSdlsrlspqmq----qyldkvrnvsASQQALG 144
WP_112178923       83 egliptnwqETLAQMN------------GGKIGNLAQSIKQNASRVDSGllnrllpaesa---sasdsfansaANAQATA 147 Rhizobiale...
tigr:CHAB381_0179 165 KERSDTIGMYSKNINKLAKKLQKSKDIKESSDLNNAIQAQVALMQAEKIQIDLYAKQRENSKNIMEDRE 233
WP_012738144      143 EKEKKASDQRVLNAQKLRAKLNVVQTPQEKQDLSLRYQQEMLELQIQQTRLQNMRALAEEKEKLADRKR 211 Candidatus Hamiltonel...
zhongguo:PT7_1774 144 ERAYDSMTRRLANVDALQNKINQTTNPKEIAELQARIQIEQANIQAEQTRIQLASQQLDAERNLLQARA 212
zhongguo:PT7_0317 147 EQAQEGIGDRMLQLDQLQQQINLATDPKAISDLQARLQVEQANIQADQIRADLLSRQLEAEKVLIEQQS 215
WP_000857358      148 DEVQNQVSQTLGEINSLSNRVALAKDSKESQDLANSIQLKSVMLNTLTTQWEMSVKAAEKRENALEAER 216 Enterobacterales
ACQ67974          159 AEVQKKINVALKDIGHLSHRIANAKDSKESQDLANAIQARSVQLNSLTSAWEMNIKAAEQRDKLLSAKR 227
WP_013318594      152 REVQDRITSTLNDIADLSDRITNAKDSKESQDLANAVAAKSVQLNALTSQWEMSVRQTEQRATLLEQQR 220 Dickeya dadantii
WP_015696806      152 SEIENKITGTLGDISDLSDRIANAQDSKESQDLANAIAAKSVQLNALTSQWEMSVKQTEQRTVLLEQQK 220 Rahnella aquatilis
CAZ15846          145 QQAYATASQRVNLLQTLTNQISSATDPKAVWDLQARIQSEQSQLQNDHSRLQSVAQLTQAQSVATKQMA 213
WP_112178923      148 GQAYELSGQRFTRLQKLMDEIGNTTDAKGIAELQARIGVEQAILQNETIKMQALAQTASAQQAIQQQQM 216 Rhizobiales bacterium
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