Members of this protein family are found in O-antigen biosynthesis loci in Leptospira, two tandem homologs in a polysaccharide biosynthesis region in the archaeon Methanoregula formicicum, in Rhizobium leguminosarum bv. trifolii WSM2297, etc. Members are more strongly conserved in the C-terminal region, where an invariant sequence PFTS is found. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
Jiyao W et al.(2023). "The conserved domain database in 2023.",