Conserved Protein Domain Family
ABC_NrtD_SsuB_transporters

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cd03293: ABC_NrtD_SsuB_transporters 
ATP-binding cassette domain of the nitrate and sulfonate transporters
NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Statistics
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PSSM-Id: 213260
Aligned: 79 rows
Threshold Bit Score: 273.193
Created: 12-Jan-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
  next features
Feature 1:ATP binding site [chemical binding site]
Evidence:
  • Comment:Walker A, Walker B, Q-loop, D-loop, and H-loop form the nucleotide binding site

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                 ## ###                                
P38053       12 LLLNAVSKHYae-------niVLNQLDLHIPAGQFVAVVGRSGGGKSTLLRLLAGLetpTAGDVLAGTtplaeiqEDTRM 84  Escherichia coli...
NP_947839     8 LSVRDVRKVFpgkg---gavpVLDGLSFDIYERDFVSIIGPSGCGKTTIFNVIAGLlnaDSGSLIYRGeqvsslrGRIGY 84  Rhodopseudomonas...
CAE27938      8 LSVRDVRKVFpgkg---gavpVLDGLSFDIYERDFVSIIGPSGCGKTTIFNVIAGLlnaDSGSLIYRGeqvsslrGRIGY 84  Rhodopseudomonas...
NP_252204    27 IEFRGVAKHFpgrgk-saatlAVQGLDLAIRRGEVVSIIGPSGCGKSTLLNMGAGLyapSEGEVRVGGervsgpvRKVSF 105 Pseudomonas aeru...
ZP_00311868   5 IKIENLSKTFkvnk---kpleVLNNINIEVYENQFVSLIGPSGCGKSTIFRILAGLekdFSGNITVNGesikassCQFGY 81  Clostridium ther...
ZP_00196623   3 LEFRGVAKQFgninsgtevltAVKDINFAVGRGEFVSVVGPSGCGKSTIMSMTAGLykpTEGEVLVSGetvvgpnSHVGF 82  Mesorhizobium sp...
NP_822515    14 LEVRGAGKAFgt-------leVLRELELSVRPGEFAAVIGPSGSGKSTLFNLISGLdtpTSGEILVDGapasvasGKVAY 86  Streptomyces ave...
YP_081965     4 LQIKDIVKSFdg-------knVLANISASIREGEFVSFVGPSGCGKSTLLNMIANIenpTSGSVTYNDkqm-qeqDVVSY 75  Bacillus cereus ZK
AAP07734      7 LQFHNVSFHYde-------kpIIHELNASIHEKEFVSIIGPSGCGKSTLFRLITGLekvSTGQIELTEtk----nHPVGY 75  Bacillus cereus ...
ZP_00322884   4 LLVQHINQSFgd-------keILHDVSLSVKPNEIVSILGVSGIGKTTLFNIIAGInqpKSGNIVFNDeditgqaGHLGY 76  Pediococcus pent...
Feature 1         #                                                                           ##
P38053       85 MFQDArLLPWKSVIDNVGLGLk------gQWRDAARRALAAVGLenragEWPAALSGGQKQRVALARALIHRPGLLLLDE 158 Escherichia coli...
NP_947839    85 MMQKDlLFPWRTVLENVLLGLrvrgvadaEALDTAREYLSTFGLsgfekAYPKTLSGGMRQRVALIRTLIMDPDILLLDE 164 Rhodopseudomonas...
CAE27938     85 MMQKDlLFPWRTVLENVLLGLrvrgvadaEALDTAREYLSTFGLsgfekAYPKTLSGGMRQRVALIRTLIMDPDILLLDE 164 Rhodopseudomonas...
NP_252204   106 MLQKDlLMPWRSIRRNIELGLeidgraagERRAIAEEMLEKCHLagfaeHYPFQLSGGMRQRAALARTLATDPQVLFLDE 185 Pseudomonas aeru...
ZP_00311868  82 MPQKDvLMPWRTVYKNIILPLeingkkdrSKKTEVENLIKEFGLegfenFYPGEISGGMKQRAGILRTFLMESDIMLLDE 161 Clostridium ther...
ZP_00196623  83 MLQKDlLLPWRSIIKNVEFGLeargvparQRRERAMAELERCHLkgfenHYPYQLSGGMRQRAALARTLAIDPDIILLDE 162 Mesorhizobium sp...
NP_822515    87 MPQKDlLFPWRTVLDNTALGLeaqgvrkkEARRRAGELFEAFGLdgfqsSYPFQLSGGMRQRAALLRTVVLERPVLLLDE 166 Streptomyces ave...
YP_081965    76 MPQQDlLLPWRSALQNIVLPLeiegkpkkQRLTEGMEALKQFELdeyadHYPDELSGGMRQRISFLRTYLCEKPIMLLDE 155 Bacillus cereus ZK
AAP07734     76 MPQKDmLLPWRTIIENAALPLecqgvqkkEAEVKAKELLHKFGLqgyekKYPKDLSGGMRQRVSFIRTLLTGGEILLLDE 155 Bacillus cereus ...
ZP_00322884  77 MLQKDlLLPFRTIMNNVILPDlvkgvkksAATARAEPLFEFFGLtgyenKYPHELSGGMKQRAALLRTFLSTKDLTLLDE 156 Pediococcus pent...
Feature 1                                       #                              
P38053      159 PLGALDALTRLEMQDLIVSLWqehgfTVLLVTHDVSEAVAMADRVLLIE--EGKIGLDLTVDI 219 Escherichia coli O157:H7
NP_947839   165 PFSALDYQTRLYLEGVLMEAVetfnkTVILITHDVDEAVALSKRVVALSgrPTRVKNVHHIDI 227 Rhodopseudomonas palustris CGA009
CAE27938    165 PFSALDYQTRLYLEGVLMEAVetfnkTVILITHDVDEAVALSKRVVALSgrPTRVKNVHHIDI 227 Rhodopseudomonas palustris CGA009
NP_252204   186 PFSALDAQTKMILQQDLARMLceqrkTALFITHDLVEAIAMSDRILVMSarPGTIVEEIEVGL 248 Pseudomonas aeruginosa PAO1
ZP_00311868 162 PFGALDAITRINMQEWLLKVLvehkkTVLFITHDIEEAIFLSDRVYVLSgrPAHVIKTLDIEF 224 Clostridium thermocellum ATCC 27405
ZP_00196623 163 PFSALDAQTKLLIQNSFAKTIqdagiTALLITHDLSEAVIMSDRVLVLSerPGTIIHELAVDI 225 Mesorhizobium sp. BNC1
NP_822515   167 PFGALDSLTRTEMQLWLADMWqryrwTVVLVTHDIREAVLLADTVHVLSprPATVVERVEVPR 229 Streptomyces avermitilis MA-4680
YP_081965   156 PFGKLDAFTKMEVHSWLLNSWhqekqTIVMVTHDLDEAILLSDRVFILSqrPASIVGEVQVKL 218 Bacillus cereus ZK
AAP07734    156 PFSALDALTKTSLQEWLFEQWqewekTILFITHDVEEALFLSNRVLVVEqqPITTLTERTVPL 218 Bacillus cereus ATCC 14579
ZP_00322884 157 PFSALDELTKRGIYQWYTDISrqmqnSTLLITHSVDEAITLSDRIYILSgkPATISHEIKITS 219 Pediococcus pentosaceus ATCC 25745

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