Conserved Protein Domain Family
CoxE2

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COG3825: CoxE2 
Uncharacterized CoxE-like protein, contains von Willebrand factor type A (vWA) domain [Function unknown]
Statistics
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PSSM-Id: 443037
Aligned: 161 rows
Threshold Bit Score: 486.942
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011280083   1 MFIKLFYTLRTYGVPVSTRELLDLNAALDQGLMmqphpedserstFASREDMYRLIRLCMVKDERHFDKFDRAMADYFEG 80 
WP_004514112   1 MFLALYHSLRALKVPVSLTEWLTLLEGLANGLH------------NQSLEDFYYLSRSLLVKDVAHYDAFDQAFAYCFKD 68 
WP_011416123   1 MFIQFFYTLREKGIPVSPTSFLRLQKALSMGLVt-------------SLEDFYMTARSILIKSERYFDLYDQIFAFHFKG 67 
WP_011736103   1 MFVSFFFTLRERGIPVTPTAFLRLQKALGLGLIt-------------SLDDFYSVARSLLVKSERDFDIYDQVFAELFRG 67 
WP_012173477   1 MFIDFFYKLKDIGVPVTPTAFLTLHRALALNLVn-------------SVDDFYTTSRTILVKSERYFDLFDQLFAHYFQG 67 
WP_041273020   1 MFITFFYKLKEVGVPVSPTAFLTLQKALDRGLVs-------------TLDDFYTTARAVLVKSERYFDLYDQVFAFCFEG 67 
WP_015949902   1 MFVPFFYILREAGVPVSPTAFLTLQKALRMGLIt-------------SIDDFYTSARAILVKSERYFDVFDQAFAHHFEG 67 
WP_013258711   1 MFLNLFYTLRHAGVPVSVTEWMTLMMALDQGHA------------DNSLSSFYYLARAILVKSEAFYDQFDQSFAHVFKD 68 
WP_014808064   1 MFVNFFFLLKDSGIPVSPTSFLRLQKALKSGLVn-------------SLNDFYTAARTILVKSERYFDIYDKVFAHYFNG 67 
WP_014959620   1 MFVKFFYTLKEIGIPVSPTSFLTLQKALNQGIIs-------------SLDDFYTCARSILVKSEKYFDLYDQVFAHHFEG 67 
WP_011280083  81 VDSLDmde--llSKl-TDIPKEWLDLKLDpKNLTDEQRRLLKKYgSLEELMKALEERLKEQKERHQGGNKWVGTGGTSPF 157
WP_004514112  69 APIPE-------DLatRKKVLEWLRDAQApRRLSEEELARLEAL-SLDELLRQLEERLRTQDGAHHGGKKWIGTGGTSPF 140
WP_011416123  68 VALTEpdiaeltDVv-RAMLEDWLKNPEDlARALGIDEKEFKKM-TPEELVQYFLDRLKDQKEEHHGGHKWIGTRGTSPV 145
WP_011736103  68 AESADeaqvmldQAv-RQLLEEWLKEPAElAKALGLTEQELASL-SGEELKQYFLDRLKDQKGVHHGGSRWIGTGGVSPV 145
WP_012173477  68 ADMPDpddweidEIm-RAMLDEWLKDPKElADMLGITPEALAQM-TPDQVVEYFKERLKDQTERHDGGNRWIGTRGTSPV 145
WP_041273020  68 VALPDssgfevdEVa-RAMLDEWLKNPKQlANALGIDPAKLADL-SPDELIDYFKQRLKDQEGRHEGGNKWIGTGGTSPV 145
WP_015949902  68 AEMPEnagveidDFl-RNLLEDWLSDPETvAEALGISEEEAAKL-SPEELLEYFKERLKDQDGRHDGGNKWIGTGGTSPV 145
WP_013258711  69 AEMPK-------NI--RDEILDWLSDPANkLELPREELERMKAL-SLEELRREFEKRLEEQTEAHHGGNRWIGTGGTSPF 138
WP_014808064  68 AELPDfrgvdldAAa-RELLDEWLKNPDAlAEALGLSKDQLQSL-SPEELIQYFLDRLKEQTEAHHGGSRWIGTGGTSPV 145
WP_014959620  68 VPLPEndgfeidEIa-RGMLDEWLKDPKRmADALGVDEEQLKKM-SPEELIEYFKERLKDQEGEHHGGYKWIGTGGYSPV 145
WP_011280083 158 GAYGDHPEGVRVGGESRKRSAAKVWEQRKYRNLDDDNQLGTRQIQMALRNLRQFARTGSADELDIHETIKRTAKK-GMLD 236
WP_004514112 141 GAGGNHPSGISFAAEGGGGRAVLQAFGRRYRNLRNDLTLDVRQIGVALKRLRDLRECGAEEHLDLEGTIDRTCRNaGEID 220
WP_011416123 146 GHSGYHPGGMRVGGRSRNKSAIKVAMERRYKDYSLDGPLTEHQMGEALKRLRQMVPEGPKDIVNVEKTIYETMRNaGEIE 225
WP_011736103 146 GHGGSRPGGMRIGGVSRKSSALKTAMERRYRDYSQDAPLTRSQMGEALKRLRHLTPSGPRDQVNVDKSIYQTMRNaGEVE 225
WP_012173477 146 GHSGTHPGGMRVGGVSRNKSAVKVAMERRYKDYSRSGPLTQAQVGEALKRLRNMVPSGPKDQVNIDKSIYHTVKNgGEIE 225
WP_041273020 146 GHSGYHPGGMRVGGESRNKSAVKVANERRYKDYSARGPLTQAMVGEALKRLRNMVPTGPRDEINIHDTIYKTMKNaGEIE 225
WP_015949902 146 GHSGVHPGGMRVGGVSRNKSAVKVAMERRYRDYSHQGPLREALMGEALKRLRHMIPVGPKDHVNVDETIYQTTRNgGEID 225
WP_013258711 139 GHSGANPAGMRIGGPGGGGTAVKIAAMRKFRNYRDDLTLDVRQMKVAMKRLRQLEREGPEDELDIDGTIDKTCRDgGEID 218
WP_014808064 146 GHSGFHPGGMRVGGRSMGRSAIKVALDRRYKDYSLEGPLTEAQMGEALKRLRRMIPVGPKDEVNVDETIRATTRNaGEIE 225
WP_014959620 146 GHSGYNPGGMRVGGRSGNKSAVKVANERRYKDYSTAGPLTQAKIGEALKRLRNMIPSGPRDTLNIDDTIKETMRNaGEIE 225
WP_011280083 237 IHMQAERRNRVKVLMLFDVGG-SMDVHIEALEKLFSAAK--NEFKTLEFFYFHNCLYDYVWKDNNRrhSAPMPTFELLNK 313
WP_004514112 221 LVFARERENQVRVLLIMDSGG-SMEPFRALSERLFSAAHglNHFRDFRAFYFHNCVYEDLYVDLDS--DESIPTAEVIRE 297
WP_011416123 226 IVHDRRMTDRLKVILMIDNGGwSMEPYIDVVQTLFNYAR--SQFKDLKIYYFHNTVYDVVWQDPQR--YYKPEFIEDFAR 301
WP_011736103 226 IVFDRRLKDKLNVLLLIDNGGwSMDPYVEIVQALFHYAE--AQFRDLSIYYYHNTIMDRVWRDPQR--RRQPERVESLLS 301
WP_012173477 226 IIFDRSLKDRLKVILAIDNGGwSMDPYVEVVQTLFDYAK--AQFKEVKTFFFHNTVYDALWKDPTR--YKEPQWVSELAR 301
WP_041273020 226 LVFDRSMRDRLKIILAIDNGGwSMDPYISVVQTLFDYAR--AQFKEVKTVFFHNTIYDHVWEDPQR--YRKPLRVDDFTR 301
WP_015949902 226 IIFERSIKDRLKVILMIDNGGwSMDPYIPVVQTLFDYSR--AQFKDIKTYFFHNTIYSAVWEDPTR--RLKPVRVREFTR 301
WP_013258711 219 LVFRRPRQNTVKVLLLMDSGG-SMNPYARLVSQLFSAAHqmSHFRDFKHYYFHNCVYQELYKDIRN--FDGEPTGSILKN 295
WP_014808064 226 IIFDRSLRDRLKVILMIDNGGwSMDPYIEVVQTLFNYAR--AQFKDLKTFFFHNTIYDFVWEDAPR--RYKPQKVEAFTS 301
WP_014959620 226 MVFDRALKDRLKVILLIDNGGwSMDPYIRVVQTLFDYAR--SQFKEVKTYFFHNTIYDHVWEDTAR--YKKPKKIIEFSR 301
WP_011280083 314 YGREYRVIFVGDASMSPYELMTVGGSVEYM--NN-------EAGIVWLKRVLAHFDKVAWLNPENPTYWQYTQTIVEIKK 384
WP_004514112 298 YGKEYRLIFVGDGAMAPYELMSPSGILERYraGT-------MSGLDWLRQLADAFGRRAWMNPLPENSWMHYETVPVVGG 370
WP_011416123 302 KDPETRLIMVGDASMAPSELMHLHGGIYFHdrSS-------TPSIERLKLLTRTFRHSVWLNPQPDWEWRHTWTIGIIQD 374
WP_011736103 302 RDPETRLIFVGDASMALEELTQIKGSISIEtrQT-------RTSLTWLNMLATSFRHSVWLNPKCSSLWDYSTTIAMIGQ 374
WP_012173477 302 RDPDTRVILVGDASMAPYELMAADGAIYLDrrGAyglkkarRSSIDNLRFIADTFSHAIWLNPVPERMWDYTQTISMIRQ 381
WP_041273020 302 RDPETRFIVLGDASMAPYELMAADGSIHVSgrSG-------KPSIERLRFIAETFAHCVWLNPVQESMWGYTHSIMAISS 374
WP_015949902 302 FDPDTRLIIIGDASMAPYELMAADGSLYVDerSG-------LASVEQLKFLAETFKHNCWFNPVPSRMWRYTQTIHNISN 374
WP_013258711 296 IGSEYKVIFVGDACMAPSELFSIGGVIDYYshND-------TPGIEWLRRFAEHFRYCVWLNPMPERTWF-HTTIQPVAR 367
WP_014808064 302 WDPETRLIVIGDASMAPYELMATDGSIHIEerSG-------LPSIDRLHLLTKLFSHAVWLNPTPIRLWPMTRTIGIIAN 374
WP_014959620 302 LDTETRLVIVGDASMSPYELLSHDGSIHISerSG-------KPSIEQLNFMAKTFPHAVWLNPVSENMWGYTHTIMAISK 374
WP_011280083 385 LFdnKMYPMTLHGVEDMTNYMAR 407
WP_004514112 371 LF--PMFPLTLEGLTRAVRHLR- 390
WP_011416123 375 VF--PMFELTLDGLEKAVKHLVS 395
WP_011736103 375 IF--PMFPLTLTGLEKAVAQLGR 395
WP_012173477 382 VF--PMFELSLDGLEQAVTHLMA 402
WP_041273020 375 VF--PMFELSLDGLEKAVSRLMI 395
WP_015949902 375 IF--PMFELTLDGLDEAVTHLMQ 395
WP_013258711 368 LI--PMFPLTLDGLERAVQRLIV 388
WP_014808064 375 IF--PMFELTLDGLDKSVTHLMR 395
WP_014959620 375 IF--SMYELSLDGLEKAVTKLMS 395
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