Conserved Protein Domain Family
thiol_BshB2

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TIGR04000: thiol_BshB2 
bacillithiol biosynthesis deacetylase BshB2
Members of this protein family are BshB2 (YojG), an enzyme of bacillithiol biosynthesis; either BshB1 (YpjG) or BshB2 must be present, and often both are present. Bacillithiol is a low-molecular-weight thiol, an analog of glutathione and mycothiol, and is found largely in the Firmicutes. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]
Statistics
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PSSM-Id: 188515
Aligned: 8 rows
Threshold Bit Score: 367.514
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012292692   7 RHILIVYPHPDDEAFSVAGTIAYYTKKmNTPVTYACLTLGEMGRNLGNPPFATRESLPEIRRKELIAAVEAMGIQDLRMM 86  Lysinibacillus ...
WP_010899461   5 RHVLVIFPHPDDEAFGVSGTIALFRKQ-GVPVTYACLTLGEMGRNLGNPPFATRESLPDIRKKELIKSAEAMGIEDLRML 83  Bacillus halodu...
WP_011229911   4 RHVLVVFPHPDDEAFGVSGTIAEHAQN-GTPVTYACLTLGEMGRNMGVPPFANRETLPHIRKQELEEACRILGIHDLRLL 82  Geobacillus
WP_011246947   5 SHVLVIFPHPDDEAFGVSGTISAYIDA-GTPVTYACLTLGQMGRNLGNPPFATRESLADIRRKELQQAAAVMGITDLRMM 83  Bacillus clausii
WP_003231215   3 EHVLVILPHPDDESYGVAGLIALNRKK-DIPVTYACATLGEMGRNMGDPFFANRETLPLLRKQELINACKEMDINDLRML 81  Bacillales
EMS37574      17 RHVLVIFPHPDDETFSSAGTLANYIQK-GIPVTYACLTLGQMGRNLGNPPFATRESLPSIRERELEEACKVIGITDLRKM 95  Staphylococcus ...
WP_011066878   3 KHVVVIYPHPDDESFGAAGSMAKFRSE-GIPVTYLCGTLGQMGRNMGNPTFANRETLPEIRKSELIKACDALDV-DLQML 80  Oceanobacillus ...
WP_011197396   3 EHVLVIMPHPDDETFAVGGTIALYAQR-GVPVTYVCGTRGEMGRRMGRPPFATRESLPGLREKELREACRILGITDLRFL 81  Symbiobacterium...
WP_012292692  87 GLRDKTIEFEDDEKMVKLVEGLIEELMPSLIITFLPGFAVHPDHEATARAVVEAVRRMPKAARPQVFGCAFANDTIEKNG 166 Lysinibacillus ...
WP_010899461  84 GYRDKTIEFEDETKLTDMVSDLMAELNPSLIITFYPGYSVHPDHEATGRAVVRAVRRLEKSMRPKLYGVAFSNGHQEELG 163 Bacillus halodu...
WP_011229911  83 GYRDKTVEFEDEEELADQIAAIVAETNPSLVITFYPGYSVHPDHDACGAAVIRALKRWPKEERPTVHCVAFAKNCEQDLG 162 Geobacillus
WP_011246947  84 GYRDKTLEFEQPGRLKQMVLDLVAELKPSLVISFYPGYAVHPDHDATGLAVASALAELPKSERPTFYAVAFSNNHEKEIG 163 Bacillus clausii
WP_003231215  82 GLRDKTLEFEDDEYLADIMEEIIDDVKPSLIVTFYPGHGVHPDHDACGEAVIRALYRKKKEDRPRTICMAITRNREEVLG 161 Bacillales
EMS37574      96 GLRDKTVEFEPYEHIDGMIKSLIDDTNPSLIISFYPGYAVHPDHEATADAVIRTVERMPKEERPRLTLVAFSNDATEALG 175 Staphylococcus ...
WP_011066878  81 GYRDKTIEFENRTEIAERLKGILEEIGPTLVITHYPDYAVHPDHNALGAAAIEAVRLMEPSERPTVWAQAISNDYELELG 160 Oceanobacillus ...
WP_011197396  82 GLWDKTVEFEDPEALAARLKAIIEEIRPSLIITYHPDYSVHPDHMALGRATVRAVAQLPPDRRPPVHTRAFGK-ASAVLG 160 Symbiobacterium...
WP_012292692 167 EPHVVYDIREMRMDKLQALQAHASQTGWM---MQETEKRIDDGEPMSESWLNVER----FYIIDP 224 Lysinibacillus sphaericus
WP_010899461 164 DPDILFDISPVAEQKKAAIRAHISQTAWM---LKDMEPKWAAQDPEALKWLHLEQ----FYSYQW 221 Bacillus halodurans
WP_011229911 163 QPDVVRDVSSVIDTKLAAIRAHRSQTEGL---MQAASKRGD-----ALAWLKTER----FWTYRW 215 Geobacillus
WP_011246947 164 PADIVHDVSAYAIRKLDTLRAHASQLAWT---LPSLEKAYYDGVEEAKERLCNER----FWTYPF 221 Bacillus clausii
WP_003231215 162 EADVVLDIKEVADIKMNALRAHRTQTEGM---LRELEEKLKNNEPVMATWFEEEI----YWTYQW 219 Bacillales
EMS37574     176 EPDIQNDITDFKELKIKAFEAHASQTGPF---LKQLASPEIDGKQH--SFLTVEP----YWTYHF 231 Staphylococcus aureus KLT6
WP_011066878 161 SPDIITDVNEFFGKKLEAILSHDSQVAGMfgkFKMLDELDEEERREIVANFGKER----FYIWQF 221 Oceanobacillus iheyensis
WP_011197396 161 EPDLVVDVRPVWETKLAAIRAHRSQSALV---LA-------DDDPEAQERLRRDRtqeaYYVWKF 215 Symbiobacterium thermophilum
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