1XJV,1QZG,1KXL


Conserved Protein Domain Family
Telo_bind

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smart00976: Telo_bind 
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Telomeric single stranded DNA binding POT1/CDC13
The telomere-binding protein forms a heterodimer in ciliates consisting of an alpha and a beta subunit. This complex may function as a protective cap for the single-stranded telomeric overhang. Alpha subunit consists of 3 structural domains, all with the same beta-barrel OB fold.
Statistics
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PSSM-Id: 214949
Aligned: 23 rows
Threshold Bit Score: 85.8326
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1XJV_A       6 YTPLNQLKGGT----IVNVYGVVKFF---KP--P----YLS-KG--T-DYCSVVTIVDQTNVK-----------LTCLLF 57   human
XP_446604  417 FKDMIIEEENTa--kFYIVFGYLLAC---STdnS----NYA-NFvfT-DFTTNRKYEQKYTFDry--------iNDYNTK 477  Candida glabrata...
1QZG_A      29 FQSIRSSQELQkkntIVNLFGIVKDF---TP--S----RQSlHG--TkDWVTTVYLWDPTCDTss-------igLQIHLF 90   fission yeast
XP_761264  381 YTPISMVRDGE----RVNMIGVIVSA---GD--A----RRS-SCgtR-DFSLKITIADASCLSgtgyakelarsITVMLF 445  Ustilago maydis 521
1KXL_A      15 FCQLGLDT-FEt--kYITMFGMLVSCsfdKP--A----FISfVF--S-DFTKN-DIVQNYLYDry--------lIDYENK 73   baker's yeast
NP_597448   10 CTKISDMTGd----kYYTIYGVVVDW---LE--W----KRC-RG--R-DFMMTLDVTDECMKK-----------LSVKIF 61   Encephalitozoon ...
XP_960651   90 raiLDDDGDAQpg-sMVNVIGVLKDC---RA--P----VAT-HG--S-DWKCTLTISDLSIEDes-------agVELVIF 148  Neurospora crass...
XP_456019  525 vrvsnivpSASs--rYYTVIGLAVTV---KY--TggktLVL-SF--T-DFTANPKVNYGY--Dsf--------lGSFQER 583  Kluyveromyces la...
XP_755945    9 HVSITTALSSSg---LVSVIGVVVDV---FGt-P----FQS-SR----SWCITFTLKDTDFGNghv-----wdgLKIKYF 67   Aspergillus fumi...
XP_961101 1674 CLPLKSIRNHLg--kNVDILASVSST---PTn-P----TRA-KGgpR-EYMMSFNVTDPSTAPth--------vVEVQMY 1733 Neurospora crass...
1XJV_A      58 SGNYEALPIIYKNGDIVRFHRL----------K----------------IQVYK--------K-------ET----QGIT 92   human
XP_446604  478 LDHDQSFRVISYYNHFNEFNMKv---------KakygkdlnamvnensqIADKNv-------S-------KY----GILC 530  Candida glabrata...
1QZG_A      91 SKQGNDLPVIKQVGQPLLLHQIt--------------------------LRSYR--------D-------RT----QGLS 125  fission yeast
XP_761264  446 AQLPESIPQNVALGHIFAIRGVh--------------------------IQMFS--------G-------KP----QAVG 480  Ustilago maydis 521
1KXL_A      74 LELNEGFKAIMYKNQFETFDSKl---------Rkif----------nngLRDLQ--------NgrdenlsQY----GIVC 122  baker's yeast
NP_597448   62 SPTK-IFSEGFCVGEVVRIGR---------------------------------------------------------LR 83   Encephalitozoon ...
XP_960651  149 RPEAR-MPEVGA-GDVLVVLSA----------K----------------VQRFKsnpkslitS-------KI----TTVC 189  Neurospora crass...
XP_456019  584 IPENEHVHALIYLNRVESLNEKlqsiikmglmE----------------CADKG--------N-------SNithrSIIF 632  Kluyveromyces la...
XP_755945   68 KANQSQLPPVR-VHDVILLRNIt--------------------------ITKFN--------G-------RP----LGVA 101  Aspergillus fumi...
XP_961101 1734 RAHKESLPIVK-PGDAILLKQVe--------------------------IRSMT--------Ag------KG----FGLR 1768 Neurospora crass...
1XJV_A      93 -S--SGFASLTFEGTLGAPIIPRTSSKYFNFT---T-E----DHKM-VEAL-RV-WAS 136  human
XP_446604  531 -R--IVMKCKLYQSVLNLVERDIELLDNLHEL---S-I----GEKPyIKEL-FN-KTE 575  Candida glabrata CBS 138
1QZG_A     126 -KdqFRYALWPDFSSNSKDTLCPQPMPRLMKT---G-D----KEEQfALLLnKI-WDE 173  fission yeast
XP_761264  481 kS--ISLWEWAIYDPVSGDVRASPSFPLASHS---P-PecsaEEMDhFRDT-AN-WFS 530  Ustilago maydis 521
1KXL_A     123 -K--MNIKVKMYNGKLNAIVRECEPVPHSQISsiaS-P----SQCEhLRLF-YQ-RAF 170  baker's yeast
NP_597448   84 -L--YDTCKAVVDRSNDVEVVFTPHTSLSSGI---S-P----RIQQlVELF-RQ-KRK 128  Encephalitozoon cuniculi GB-M1
XP_960651  190 -V--YKAATIPVYPASAQVALLPPKQGESHKL---LkE----EHHQyVSYL-YN-VId 235  Neurospora crassa OR74A
XP_456019  633 -K--FTVKCQLFQGKLNTVILDADPITPTTPV---T-T----EEYKlLKPL-RN-KIF 677  Kluyveromyces lactis NRRL Y-1140
XP_755945  102 pD--ETTILWAIYRPEPGFVDISPICGPVPFE---P-Sy---SEKSyALSL-ID-KSS 148  Aspergillus fumigatus Af293
XP_961101 1769 -T--GEGSAWAVFEATPEEDKEEEG----EKD---G-G----DATA-ATTF-RPpQIK 1809 Neurospora crassa OR74A
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